Patents by Inventor Curis, Inc.

Curis, Inc. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mediators of Hedgehog Signaling Pathways, Compositions and Uses Related Thereto
    Publication number: 20130190350
    Abstract: The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.
    Type: Application
    Filed: December 12, 2012
    Publication date: July 25, 2013
    Applicant: CURIS, INC.
    Inventor: Curis, Inc.
  • TREATMENT OF CANCERS HAVING K-RAS MUTATIONS
    Publication number: 20130102595
    Abstract: The present invention provides a method of treating a cancer associated with a K-ras mutation in a subject in need thereof. The method comprises the steps of: (1) identifying a subject with a cancer associated with a K-ras mutation; and (2) administering to the subject (i) an inhibitor of PI3 kinase and (ii) an HDAC inhibitor, wherein the PI3 kinase inhibitor and the HDAC inhibitor are administered in amounts which together are therapeutically effective.
    Type: Application
    Filed: October 15, 2012
    Publication date: April 25, 2013
    Inventor: Curis, Inc.