Abstract: A method of processing medical image data to predict disease progression in non-small cell lung cancer (NSCLC) patients includes receiving a multiplexed tissue image comprising a plurality of cells stained for one or more markers, evaluating the multiplexed tissue image using a machine learning model, and predicting whether a patient's NSCLC will progress based on the evaluation of the multiplexed tissue image using the machine learning model.

Abstract: A system includes processing circuitry and a drone. The drone includes a dispenser subassembly that includes a housing comprising an aerosol dispensing system and configured to receive a syringe such that an applicator of the syringe is positioned distally from the housing; a trigger that is positioned in contact with a nozzle of the aerosol dispensing system; an actuator arm; and an actuator motor configured to move the actuator arm in a reciprocating motion. Control logic of the drone is configured to navigate, based on navigation instructions received from the processing circuitry, the drone to an area associated with an object of potential survey interest (OoPSI) such that the applicator of the syringe or the nozzle of the aerosol dispensing system is proximate to the area associated with the OoPSI.

Abstract: The present disclosure relates to a telecommunications connector. The connector includes at least one connector portion including a front housing portion coupled to a rear housing portion. The front housing portion defines a front end and a rear end, the front housing portion including a ferrule terminating a cable fixed to the at least one connector portion, the front housing portion further including a latch that is configured to contact a fiber optic adapter for locking the connector to the fiber optic adapter when the connector is inserted into the fiber optic adapter, wherein the latch is movable about a connection location on the front housing portion. The latch defines a permanently attached rear extension that extends rearward past the rear end of the front housing portion, the rear extension configured to be contacted for moving the latch for freeing the connector from the fiber optic adapter.

Abstract: A pharmaceutical drug delivery device and method of preventing drying out and drooling of an ejection head for the drug delivery device. The device includes a device body; a fluid outlet nozzle attached to the device body; and a fluid jet ejection cartridge containing a liquid pharmaceutical drug disposed in the body. A fluid ejection head is attached to the fluid jet ejection cartridge and is in fluid flow communication with the fluid outlet nozzle. An elongate, serpentine air flow path disposed between an inner surface of the fluid outlet nozzle and a sealing material that is disposed between an outer surface of the fluid jet ejection cartridge and the inner surface of the fluid outlet nozzle, wherein the elongate, serpentine air flow path provides a reduced pressure differential adjacent to a surface of the ejection head upon use of the drug delivery device and provides a humidification zone.

Abstract: In one embodiment, one or more suspension systems of a vehicle may be used to mitigate motion sickness by limiting motion in one or more frequency ranges. In another embodiment, an active suspension may be integrated with an autonomous vehicle architecture. In yet another embodiment, the active suspension system of a vehicle may be used to induce motion in a vehicle. The vehicle may be used as a testbed for technical investigations and/or as a platform to enhance the enjoyment of video and/or audio by vehicle occupants. In some embodiments, the active suspensions system may be used to perform gestures as a means of communication with persons inside or outside the vehicle. In some embodiments, the active suspensions system may be used to generate haptic warnings to a vehicle operator or other persons in response to certain road situations.

Abstract: An optical system includes a light source, an optical film curved about a first axis, and a light control film curved about the first axis and disposed between the light source and the optical film. The optical film includes a microstructured first major surface and an opposing second major surface. The microstructured first major surface defines a linear Fresnel lens including a plurality of Fresnel elements extending longitudinally along the first axis. The first major surface of the optical film faces the light control film. The light control film includes a plurality of alternating optically transmissive and optically absorptive regions extending longitudinally along the first axis such that in a cross-section orthogonal to the first axis, for at least a majority of the optically transmissive regions, a centerline between adjacent optically absorptive regions is substantially normal to a major surface of the light control film.

Abstract: In an example, a computer implemented method includes obtaining respective transactional data from each financial data source of a plurality of financial data sources, where the respective transactional data is each associated with a posting time. The method also includes determining a net liquidity amount from the respective transactional data based on the posting time of each of the respective transactional data. The method also includes outputting net liquidity data that is representative of the determined net liquidity amount.

Abstract: A surgical system uses a single entry port in a wide variety of surgeries. To insert multiple surgical instruments into a patient through a single entry port requires that the shaft of at least one of the surgical instruments be bent between the base of the surgical instrument and the point where the shaft contacts a channel in an entry guide. Each surgical instrument is positioned by an instrument manipulator positioning system so that when the shaft is inserted in a channel of the entry guide, any bending of the shaft does not damage the surgical instrument and does not inhibit proper operation of the surgical instrument.

Abstract: Light controlled switching modules are provide. In embodiments, a light controlled switching module includes: a housing; a light controlled semiconductor switch mounted to the housing, the light controlled semiconductor switch including a semiconductor body; at least one light source mounted to the housing in a spaced relationship from the light controlled semiconductor switch and positioned to direct light emitted from the at least one light source toward the semiconductor body; and first and second electrodes mounted to the housing and connected to the light controlled semiconductor switch, wherein the first and second electrodes are configured to have variable resistance between the first and the second electrode.

Abstract: A storage and display assembly with a base defining a cavity configured to receive a product. A lid is mounted to the base covering the cavity. A hang tag is mounted to the base. The hang tag has a first position with a first end of the hang tag engaging an inner surface of the lid securing the lid to the base and a second position with the first end of the hang tag is disengaged from the inner surface of the lid.

Abstract: A system includes a first sensor positioned to sense presence of a contrail in a first volume, wherein the first volume at least partially overlaps an expected volume of a contrail proximate an aircraft. A second sensor is positioned to sense a background reference in a second volume, where the second volume does not overlap the expected volume of a contrail proximate an aircraft. A controller is operatively connected to the first and second sensors. The controller includes machine readable instructions configured to cause the controller to utilize data input from both the first and second volumes to determine if a contrail is present from the aircraft. A system includes machine readable instructions configured to cause the controller to predict persistence of contrails on an intended route through the volume of airspace and to determine an improved route and/or propulsion operation to reduce contrail formation and persistence relative to the intended route.

Abstract: A disposable stethoscope cover system includes a clamp which is configured to be mechanically attachable to stethoscope tubing; and a disposable cover which is configured to be mechanically attachable to the clamp. According to an embodiment, a clip and clamp mechanism is configured to releasably attach a stethoscope cover to a stethoscope and includes a clamp mechanism configured to be press fit to the stethoscope tubing to connect the clamp and clamp mechanism to the stethoscope; and a clip mechanism which is configured to releasably grasp a portion of the stethoscope cover.

Abstract: This document relates to materials and methods involved in treating cancer. For example, materials and methods for using one or more oncolytic viruses (e.g., one or more oncolytic viruses) to treat cancer in a mammal (e.g., a human) identified as having a cancer likely to respond to oncolytic virotherapy are provided.

Abstract: A universal joint (U-joint) assembly transmits torque from a drive component to a driven component across an articulating joint. The U-joint assembly includes male and female U-joint members, a central ball joint, and a retaining device configured to secure the assembly in an assembled configuration. The female U-joint member includes a cavity extending into a receptacle end thereof. The cavity terminates in a circular receptacle and includes a plurality of rectangular channels extending radially outward from the cavity at equal intervals, each channel defined by three planar drive surfaces. The male U-joint member has a drive end with a plurality of corresponding rectangular extensions protruding from an outer periphery of the drive end, each extension including a plurality of axial angular surfaces. When assembled, each of the angular surfaces of the drive end opposes a corresponding one of the drive surfaces of the cavity. Other embodiments are also disclosed.

Abstract: Methods and systems are provided for locking assemblies of a pair of bridge plates placed between adjacent railcars. In one example, a bridge plate assembly may include a locking assembly with a guide tube shifted to a side from a center of a bridge plate and a pivot pin coupled to the guide tube protruding out of a left side or a right side of the bridge plate.

Abstract: In accordance with at least one aspect of this disclosure, a method of detecting a fault in a plurality of optical detectors includes receiving a first return beam from a first optical detector interrogation beam to generate a first optical signal indicative of an atmospheric condition from a first location on board the aircraft and receiving a second return beam from a second optical detector interrogation beam to generate a second optical signal indicative of the atmospheric condition from a second location on board the aircraft. The method includes, comparing each of the first and second optical signals with a baseline value to determine whether there is a fault in at least one optical detector of the plurality of optical detectors.

Abstract: An optical film includes a structured film and a light control film formed on the structured film. The structured film includes a substrate and a plurality of polymeric microstructures formed on a major surface of the substrate. Each microstructure includes an optical facet and a sidewall meeting the optical facet at a ridge of the microstructure. The light control film includes an optically transparent material disposed on and covering the plurality of polymeric microstructures, and a plurality of optically absorptive louvers formed in the optically transparent material opposite the structured film. The louvers extend along a longitudinal direction and are spaced apart along an orthogonal transverse direction. The louvers have an average depth D into the optically transparent material and have an average width W in the transverse direction. D/W can be greater than 2. The optical film is integrally formed.

Abstract: Techniques herein facilitate dynamic configuration of a wireless local area network (WLAN) for large public venue (LPV) environments. In one example, a method may include providing an initial configuration for access points APs of a WLAN for an event at an LPV based on a profile for the event, a location of each AP for the venue, and anticipated demand at the APs; determining, for a particular time for the event, a distribution of wireless devices and channel support capabilities of the wireless devices different locations for the LPV; and providing an updated configuration for one or more APs at the one or more locations for the venue based on the distribution of the wireless devices and the channel support capabilities of the wireless devices determined for the particular time for the event at the LPV.

Abstract: A stationary bike capable of leaning of tilting side to side during use is described. The stationary bike has a fixed frame portion and moving frame portion which is pivotally mounted on the fixed frame portion, at two spaced apart pivot locations, to allow the moving frame to pivot about a pivot axis defined by the two spaced apart pivot locations. The pivotal action of the bike may be resisted, such as by a damper. The tilt-enabled bike is equipped with a tilt disabling mechanism, e.g., a locking mechanism configured to selectively and operatively engage the moving and the fixed frame to disable the relative movement (i.e. the pivoting) of the moving frame.

Abstract: Disclosed is a structure with ultralow-K (ULK) dielectric-gap wrapped contact(s). The structure includes an opening, which extends through a dielectric layer and is aligned above a device. A contact is within the opening and electrically connected to the device. Instead of the contact completely filling the opening, a ULK dielectric-gap (e.g., an air or gas-filled gap or a void) at least partially separates the contact from the sidewall(s) of the contact opening and further wraps laterally around the contact. Also disclosed is a method for forming the structure and, particularly, for forming a ULK dielectric-gap by etching back an exposed top end of an adhesive layer initially lining a contact opening to form a gap between the sidewall(s) of the opening and the contact and then capping the gap with an additional dielectric layer such that the gap is filled with air or gas or is under vacuum.