Abstract: A tissue separation apparatus is disclosed. The apparatus can have a separating member that has a contracted state and an expanded state. When the separating member is placed between first and second tissue layers, the separating member can part the first tissue layer from the second tissue layer. The separating member can be moved into the contracted state to sever the first tissue layer. Methods of making and using the prosthesis are also disclosed.

Abstract: Non-expandable space-occupying devices for treating voids within the body are disclosed. The devices can have multiple non-expandable space-occupying elements connected to a flexible leader. Methods of making and using the devices are also disclosed.

Abstract: A biologically implantable prosthesis is disclosed. The prosthesis can have a circumferentially expandable wall and elements that prevent the wall from collapsing once the wall is expanded. Methods of making and using the prosthesis are also disclosed.

Abstract: Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot near a distal end of a shaft is inserted through the penetration and actuated so that the foot extends along the lumenal axis. The foot carries suturing attachment cuffs, and needles are advanced from the shaft through the vessel wall outside of the penetration and into engagement with the needle cuffs after the foot has been drawn proximally up against the endothelial surface of the blood vessel. The cross-section of the shaft within the tissue tract can be minimized by laterally deflecting the needles as they leave the shaft, while tapered depressions within the foot can guide the advancing needles into engagement with the cuffs. The cuffs lockingly engage the needles and can be withdrawn proximally along the needle paths and through the tissue tract so as to form a loop of suture across the puncture.

Abstract: A biologically implantable prosthesis is disclosed. The prosthesis can have a circumferentially expandable wall and elements that prevent the wall from collapsing once the wall is expanded. Methods of making and using the prosthesis are also disclosed.

Abstract: Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot near a distal end of a shaft is inserted through the penetration and actuated so that the foot extends along the lumenal axis. The foot carries suturing attachment cuffs, and needles are advanced from the shaft through the vessel wall outside of the penetration and into engagement with the needle cuffs after the foot has been drawn proximally up against the endothelial surface of the blood vessel. The cross-section of the shaft within the tissue tract can be minimized by laterally deflecting the needles as they leave the shaft, while tapered depressions within the foot can guide the advancing needles into engagement with the cuffs. The cuffs lockingly engage the needles and can be withdrawn proximally along the needle paths and through the tissue tract so as to form a loop of suture across the puncture.

Abstract: Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot near a distal end of a shaft is inserted through the penetration and actuated so that the foot extends along the lumenal axis. The foot carries suturing attachment cuffs, and needles are advanced from the shaft through the vessel wall outside of the penetration and into engagement with the needle cuffs after the foot has been drawn proximally up against the endothelial surface of the blood vessel. The cross-section of the shaft within the tissue tract can be minimized by laterally deflecting the needles as they leave the shaft, while tapered depressions within the foot can guide the advancing needles into engagement with the cuffs. The cuffs lockingly engage the needles and can be withdrawn proximally along the needle paths and through the tissue tract so as to form a loop of suture across the puncture.

Abstract: Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot near a distal end of a shaft is inserted through the penetration and actuated so that the foot extends along the lumenal axis. The foot carries suturing attachment cuffs, and needles are advanced from the shaft through the vessel wall outside of the penetration and into engagement with the needle cuffs after the foot has been drawn proximally up against the endothelial surface of the blood vessel. The cross-section of the shaft within the tissue tract can be minimized by laterally deflecting the needles as they leave the shaft, while tapered depressions within the foot can guide the advancing needles into engagement with the cuffs. The cuffs lockingly engage the needles and can be withdrawn proximally along the needle paths and through the tissue tract so as to form a loop of suture across the puncture.

Abstract: Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot near a distal end of a shaft is inserted through the penetration and actuated so that the foot extends along the lumenal axis. The foot carries suturing attachment cuffs, and needles are advanced from the shaft through the vessel wall outside of the penetration and into engagement with the needle cuffs after the foot has been drawn proximally up against the endothelial surface of the blood vessel. The cross-section of the shaft within the tissue tract can be minimized by laterally deflecting the needles as they leave the shaft, while tapered depressions within the foot can guide the advancing needles into engagement with the cuffs. The cuffs lockingly engage the needles and can be withdrawn proximally along the needle paths and through the tissue tract so as to form a loop of suture across the puncture.

Abstract: A pneumatic pump having a variable buoyant actuator to substantially reduce the volume of a float, thereby increasing the fluid capacity for any pump of a given size. The pump includes an elongated housing, a sealable fluid entry aperture and a pipe communicating between an interior and an exterior of the housing. The housing includes a bottom wall and a cylindrical side wall extending from the bottom wall and terminating in an opening. A switchable valve control having a pod closes the opening. The pod has a plurality of valve seats and a plurality of corresponding valve elements, with the plurality of valve seats defining fluid inlet and output ports. The actuator is coupled to alternatingly placed valve elements in sealing engagement with fluid inlet and outlet ports in response to a level of fluid in the housing. The variable buoyant actuator includes first buoyant member disposed proximate to the bottom wall, and a buoyant amplifier disposed opposite to the first buoyant member, proximate to the pod.

Abstract: A floatless pneumatic pump having an elongated housing including a sealable fluid entry aperture and a pipe communicating between an interior and an exterior of the housing, with the housing movably attached to the pipe for axial displacement therewith. The housing includes a bottom wall and a cylindrical side wall extending from the bottom wall and terminating in an opening. A switchable valve control having a pod closes the opening. The pod has a plurality of valve seats and a plurality of corresponding valve elements, with the plurality of valve seats defining at least one fluid inlet port and at least one fluid outlet port. The valve elements alternatingly seal the inlet and outlet ports in relation to the axial displacement of the housing, allowing both fluid to ingress through a sealable fluid entry aperture and fluid to egress through the pipe.

Abstract: A tactile micro-gripper is disclosed having a combined lever and spring linkage. The lever flexes at predetermined points and is coupled to the spring and to an actuator. The spring is of a parallelogram type, so that the ends remain parallel to one another when the spring is bent. When the actuator causes the lever to move transversely, the end of the spring is caused to move laterally in a parallel manner. A pair of lever and spring linkages are arranged together so that they cooperatively act together to manipulate a pair of fingers, which are attached to the ends of the springs, to grip and release objects. Tactile sensing is accomplished by means of a cantilever beam and an optical detection system disposed in the tip of the fingers.