Patents by Inventor D. Marshall Porterfield

D. Marshall Porterfield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240149279
    Abstract: Centrifuge systems including free-flying centrifuges for mass separations in high gravity, microgravity, or zero gravity environments are described. A centrifuge system includes a body and a rotary member. The body includes a first vertical thruster selectively operable to move the body in a first direction parallel to the central axis, and one or more position sensors configured to determine a position of the body within an open space. The rotary member is configured to receive one or more material samples. The rotary member or body includes a first horizontal thruster selectively operable to move the body in a first direction perpendicular to the central axis, and the rotary member includes a rotational thruster selectively operable to rotate the rotary member about the central axis.
    Type: Application
    Filed: November 6, 2023
    Publication date: May 9, 2024
    Inventors: D. Marshall Porterfield, Madelyn Julia Whitaker, Alessandro Jesus Paz Hernández, Autumn Frances Wuebben, Kyra Rose Keenan, Mitchell R. Hekstra, Dominic Lovisa, Ajay Dalal, William Schoenfeld, Hunter Moyer, Ethan Fry
  • Patent number: 8882977
    Abstract: Glucose and ATP biosensors have important applications in diagnostics and research. Combining single-walled carbon nanotubes (SWCNTs) with Pt nanoparticles can significantly enhance the performance of electrochemical biosensors. This disclosure illustrates the use of single-stranded DNA (ssDNA) to modify SWCNTs to increase SWCNT solubility in water. Multiple embodiments with this configuration allows for exploration of new schemes of combining ssDNASWCNT and Pt black in aqueous media systems. These embodiments resulted in a nanocomposite with enhanced biosensor performance. The ssDNA-SWCNT/Pt black nanocomposite constructed by a layered scheme proved most effective in terms of biosensor activity. The key feature of this structure and method of use is the exploitation of ssDNASWCNTs as molecular templates for Pt black electrodeposition. Glucose and ATP microbiosensors fabricated utilizing this structure and method of use exhibited high sensitivity, wide linear range and low limit of detection.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: November 11, 2014
    Assignee: Purdue Research Foundation
    Inventors: D. Marshall Porterfield, Tae-Gon Cha, Jong Hyun Choi, Jonathan C. Claussen, Alfred R. Diggs, Jin Shi
  • Patent number: 8715981
    Abstract: Networks of single-walled carbon nanotubes (SWCNTs) decorated with Au-coated Pd (Au/Pd) nanocubes are employed as electrochemical biosensors that exhibit excellent sensitivity (2.6 mA mM?1 cm?2) and a low estimated detection limit (2.3 nM) at a signal-to-noise ratio of 3 (S/N=3) in the amperometric sensing of hydrogen peroxide. Biofunctionalization of the Au/Pd nanocube-SWCNT biosensor is demonstrated with the selective immobilization of fluorescently labeled streptavidin on the nanocube surfaces via thiol linking. Similarly, glucose oxidase (GOx) is linked to the surface of the nanocubes for amperometric glucose sensing. The exhibited glucose detection limit of 1.3_M (S/N=3) and linear range spanning from 10 ?M to 50 mM substantially surpass other CNT-based biosensors.
    Type: Grant
    Filed: January 27, 2010
    Date of Patent: May 6, 2014
    Assignee: Purdue Research Foundation
    Inventors: Jonathan Clay Claussen, Aaron D. Franklin, Timothy S. Fisher, D. Marshall Porterfield
  • Publication number: 20100285514
    Abstract: Networks of single-walled carbon nanotubes (SWCNTs) decorated with Au-coated Pd (Au/Pd) nanocubes are employed as electrochemical biosensors that exhibit excellent sensitivity (2.6 mA mM?1 cm?2) and a low estimated detection limit (2.3 nM) at a signal-to-noise ratio of 3 (S/N=3) in the amperometric sensing of hydrogen peroxide. Biofunctionalization of the Au/Pd nanocube-SWCNT biosensor is demonstrated with the selective immobilization of fluorescently labeled streptavidin on the nanocube surfaces via thiol linking. Similarly, glucose oxidase (GOx) is linked to the surface of the nanocubes for amperometric glucose sensing. The exhibited glucose detection limit of 1.3_M (S/N=3) and linear range spanning from 10 ?M to 50 mM substantially surpass other CNT-based biosensors.
    Type: Application
    Filed: January 27, 2010
    Publication date: November 11, 2010
    Inventors: Jonathan Clay Claussen, Aaron D. Franklin, Timothy S. Fisher, D. Marshall Porterfield
  • Publication number: 20090305888
    Abstract: The present invention provides compositions and methods for resolving bioavailable oxygen supply to plants subjected to hypoxic stresses. Compositions of the invention comprise an oxidizing agent, wherein the level and rate of oxygen released from the composition is controlled. Use of the compositions of the invention address hypoxic stress and also stimulate plant growth, enhance plant vigor, and/or improve crop yield.
    Type: Application
    Filed: January 29, 2007
    Publication date: December 10, 2009
    Inventors: Yuncong Li, Guodong Liu, D. Marshall Porterfield