Abstract: Endovascular valve formation systems with imaging capabilities and associated devices and methods are disclosed herein. In some embodiments, a valve formation and imaging system can include, for example, (i) a valve formation device configured to access a vessel wall and dissect a portion of the vessel wall to form an autologous valve leaflet and (ii) an imaging device configured to image the vessel wall and components of the valve formation device during a valve formation procedure. In some embodiments, the imaging device is integrated into a distal end portion of the valve formation device. In some embodiments, the imaging device is a separate catheter device positionally coupled to the valve formation device and/or components thereof.

Abstract: Described herein are compounds that inhibit ALK2 and its mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.

Abstract: An imaging system, such as a surgical microscope, laparoscope, or endoscope or integrated with these devices, includes an illuminator providing patterned white light and/or fluorescent stimulus light. The system receives and images light hyperspectrally, in embodiments using a hyperspectral imaging array, and/or using narrowband tunable filters for passing filtered received light to an imager. Embodiments may construct a 3-D surface model from stereo images, and will estimate optical properties of the target using images taken in patterned light or using other approximations obtained from white light exposures. Hyperspectral images taken under stimulus light are displayed as fluorescent images, and corrected for optical properties of tissue to provide quantitative maps of fluorophore concentration. Spectral information from hyperspectral images is processed to provide depth of fluorophore below the tissue surface. Quantitative images of fluorescence at depth are also prepared.

Abstract: A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.

Abstract: A solar panel system includes solar tracking and dual locking hinges. A solar panel assembly may be connected to a base via a linear actuator, actuator arm, and lever arm, which in connection of either of the two locking hinges acting as an axis of rotation, form a toggle joint mechanism for tilting the solar panel assembly to a desired angle in a desired direction. The desired angle may be automatically determined using solar tracking algorithms using data from light sensors, or may be controlled manually by a user. The locking hinges may include electromagnetic locks, which may lock the associated hinge to the base when energized, and unlock the associated hinge when de-energized. To tilt the solar panel assembly in one of two directions, one hinge is locked and the other unlocked, allowing the unlocked end to move upward to achieve the desired tilt angle.

Abstract: Low profile object detection can be performed on mowers or other vehicles that may be autonomous. An autonomy controller can be employed on a mower to receive and process sensor data for a detection area to determine whether an object may be present in a region of interest within the detection area. When the autonomy controller determines that an object may be present, it can cause the ground speed of the mower to be slowed and can commence buffering region of interest sensor data over a period of time. The autonomy controller can process the buffered region of interest sensor data to determine whether an object is present in the region of interest, and if so, can alter the path of the mower appropriately.

Abstract: A method of producing an alcohol ethoxylate surfactant or lubricant, the method including reacting a low molecular weight initiator with ethylene oxide in the presence of a polymerization catalyst, the low molecular weight initiator having a nominal hydroxyl functionality at least 1, and the polymerization catalyst being a Lewis acid catalyst having the general formula M(R1)I(R2)I(R3)I(R4)0 or 1, whereas M is boron, aluminum, indium, bismuth or erbium, R1, R2, R3, and R4 are each independent, R1 includes a first fluoroalkyl-substituted phenyl group, R2 includes a second fluoroalkyl-substituted phenyl group or a first fluoro/chloro-substituted phenyl group, R3 includes a third fluoroalkyl-substituted phenyl group or a second fluoro/chloro-substituted phenyl group, and optional R4 includes a functional group or functional polymer group, R1 being different from at least one of R2 and R3.

Abstract: A computer readable media, a method, and a system registering a third party application providing an available communication system between a local user and a remote user identity, storing information related to the available communication system in a first database, obtaining contact information for the remote user identity from the third party application, determining a communication type for the third party application, pairing the remote user identity with a contact, and updating a graphical representation of contact information.

Abstract: Systems, methods, and computer-readable storage devices are disclosed for simulated choral audio chatter in communication systems. One method including: receiving audio data from each of a plurality of users participating in a first group of a plurality of groups for an event using a communication system; generating first simulated choral audio chatter based on the audio data received from each of the plurality of users in the first group; and providing the generated first simulated choral audio data to at least one user of a plurality of users of the event.

Abstract: A process of making a fuel product as an additive from a non-auto-combustible high protein organic material for the destruction of polyfluoro compounds in a thermal process system is provided. Thermal reactions within thermal reaction equipment are controlled by controlling the moisture and oxygen in the reaction atmosphere of the equipment and energy inputs at or downstream of a thermal reaction chamber. The concentration of protein thermal decomposition by-products, temperature, and residence time and/or additions of energy within the thermal reaction equipment environment are controlled to destroy hazardous polyfluoro compounds.

Abstract: A detector for detecting the removal and/or insertion of a weapon out of and/or into a holster. The detector may transmit a message each time the weapon is removed from the holster. A recording system may receive the message and determine whether or not it will begin recording the data it captures. A detector may detect the change in a magnitude of an inductance and/or an impedance of a circuit to detect insertion and removal of the weapon into and out of the holster. The holster is configured to couple to the detector to position the detector to detect insertion and removal of the weapon. An adhesive tape may couple a detector to a holster.

Abstract: A fixation component includes tines extending from a base portion of the fixation component. Each tine is elastically deformable between a pre-set position and an open position. Each tine includes a hook segment extending from a proximal end near the base portion to a distal end. Each tine also includes a distal segment extending from the distal end of the hook segment to a tissue-piercing tip. When positioned in the pre-set position, the hook segment extends along a pre-set curvature that encloses an angle between 135 degrees and 270 degrees, and the distal segment extends away from a longitudinal axis of the fixation component.

Abstract: A vacuum cleaner assembly is provided that includes a body extending along an axis to a base connection end that includes a protrusion. A handle extends from the body opposite the base connection end. A dust collection portion includes a body connection end that includes a track with a lock passage extending perpendicularly from the track. The protrusion is located in the lock passage in a locked position and in the track in an unlocked position to selectively remove the dust collection portion from the body.

Abstract: A blade grinder that includes a base unit having a housing. The housing encloses a drive motor and defines a receiving cavity. A battery receiver is defined along a portion of the housing and a battery is removably coupled to the battery receiver. A blade implement is disposed within the receiving cavity, wherein the blade implement is configured to be driven by the drive motor. A bowl is positionable in an operably disposed condition within the receiving cavity. A lid is couplable to the housing to retain the bowl in the operably disposed condition within the receiving cavity.

Abstract: A cordless appliance includes a blender having a base unit with a housing and an upwardly opening upper cavity. A drive connection is positioned within the upwardly opening upper cavity. The housing further includes a battery-receiving cavity that is configured to receive a removable battery. A motor is disposed within the housing of the base unit it is contemplated to be powered by the removable battery. A blender jar includes an upper collar in an interior cavity. A first lid assembly is configured to be coupled to the upper collar of the blender jar and includes a blade assembly and a drive connecting member. A second lid assembly includes a cap member removably received on an open aperture of the second lid assembly. The first and second lid assemblies are configured for limited rotation with respect to the blender jar for engagement of the same.

Abstract: A dual-drive co-rotating scroll device includes a housing; a first scroll rotatably mounted within the housing via a first cylindrical extension and a first plurality of bearings, and having a first axis of rotation; and a second scroll rotatably mounted within the housing via a second cylindrical extension and a second plurality of bearings, and having a second axis of rotation different than the first axis of rotation. At least one of the first cylindrical extension and the second cylindrical extension may comprise a plurality of permanent magnets and operate as a rotor of a first motor. An Oldham ring may be positioned between the first scroll and the second scroll and configured to maintain a relative angular position between the first scroll and the second scroll.

Abstract: A gas turbine engine including a core having a compressor section fluidly connected to a combustor via a primary flowpath and a turbine section connected to the combustor via the core flow path. An assembly is disposed within the gas turbine engine and includes a first part connected to a second part via a radial stack joint. The first part includes a radially inward facing surface contacting a corresponding radially outward facing surface of the second part. A fastener protrudes through the first part and the second part and is configured to maintain the relative positions of the first part and the second part. A channel is disposed on at least one of the radially inward facing surfaces and is positioned between the fastener and a circumferential edge of the first part. The channel is connected to at least one cooling air source.

Abstract: An intravascular access system for facilitation of intraluminal medical procedures within the neurovasculature through an access sheath. The system includes an aspiration or support catheter having a flexible, distal luminal portion having an inner diameter defining a lumen extending between a proximal opening at a proximal end of the luminal portion and a distal opening at a distal end of the luminal portion. The catheter has a rigid spine coupled to at least the proximal end of the luminal portion and extending proximally therefrom. The system includes a dilator having a flexible, distal dilator portion sized to be received within the lumen of the luminal portion. Associated systems, devices, and methods of use are also described.

Abstract: A thermally reflective membrane apparatus comprises a housing structure, and a thermally reflective membrane contained within the housing structure. The thermally reflective membrane comprises a semipermeable structure, and a porous, thermally reflective structure physically contacting the semipermeable structure. The porous, thermally reflective structure comprises discrete thermally reflective particles, and a binder material coupling the discrete thermally reflective particles to one another and the semipermeable structure. A fluid treatment system and method of treating a fluid are also described.

Abstract: Methods, systems, and devices for facilitation of intraluminal medical procedures within the neurovasculature, the methods, systems and the devices including catheters and catheter advancement elements.