Abstract: Disclosed are novel compounds of Chemical Formula 1, optical isomers of the compounds, and pharmaceutically acceptable salts of the compounds or the optical isomers. The compounds, isomers, and salts exhibit excellent activity as GLP-1 receptor agonists. In particular, they, as GLP-1 receptor agonists, exhibit excellent glucose tolerance, thus having a great potential to be used as therapeutic agents for metabolic diseases. Moreover, they exhibit excellent pharmacological safety for cardiovascular systems.

Abstract: Proposed is a non-fixing implant made of a raw material including a biomaterial and a ceramic-based composite material having excellent osteoconductivity in addition to a polymer. The non-fixing implant can be accurately secured to a gap between the skull and the bone flap and can be conveniently used. Further proposed is a method of manufacturing the non-fixing implant. The non-fixing implant includes a flexible wedge deformable to conform to the external contour of the bone flap and a plurality of wings connected to an upper or lower portion of the flexible wedge and extending to both sides of the flexible wedge. The wings have a porous structure. The wings on one side will be positioned on the bone flap and the wings on the other side will positioned on the skull. The non-fixing implant has the advantage of being capable of accurately filling a defect formed by craniotomy, has improved biocompatibility and bone bonding ability, and allows tissue invasion.

Abstract: The present invention relates to: an implant for the reconstruction of the nipple-areola complex; and a method for producing same. The implant for the reconstruction of the nipple- areola complex according to the present invention can be implanted along a central axis inside autologous tissue during nipple-areola complex reconstruction surgery to form a normal nipple-areola complex shape. In addition, the nipple-areola complex implant according to the present invention, due to being formed of a porous structure, has similar flexibility to normal nipple-areola complex tissue, and exhibits a high engraftment rate with autologous tissues since the surrounding tissue can permeate into the implant through the voids thereof following implantation.

Abstract: An ampoule for storing an implant capable of maintaining humidity includes: a container capable of airtight sealing at least momentarily or temporarily; a partition member which divides an accommodation space inside the container into two spaces, first and second spaces, and allows vaporized water molecules to be transported between the divided spaces; and a water molecule supply source which is accommodated in the first space of the two spaces divided by the partition member and supplies the vaporized water molecules. Therefore, the invention enables the construction of an environment which allows the hydrophilicity of the implant to be maintained for a long time, wherein the hydrophilicity is imparted to and protected from the surface of the implant or a coating layer formed on the surface of the implant.

Abstract: A hydrogel and a method for manufacturing the same. The hydrogel, which can be freely used during treatment irrespective of the shape of a bone defect region, has a decomposition rate capable of being regulated in situ and can thus be rapidly decomposed over a certain time, i.e., after the completion of bone regeneration. Furthermore, a hydrogel membrane using the hydrogel which is applied to a bone defect region irrespective of the shape thereof, and a method for manufacturing the same.

Abstract: A dental bleaching composition includes a dental bleaching agent, a binder, a tartrate, and a solvent.

Abstract: The present invention relates to a dental hydrogel and to a method for manufacturing same, and more particularly, to a hydrogel and to a method for manufacturing wherein the hydrogel, which can be freely used during treatment irrespective of the shape of a bone defect region, has a decomposition rate capable of being regulated in situ and can thus be rapidly decomposed over a certain time, i.e., after the completion of bone regeneration. Furthermore, the present invention relates to a hydrogel membrane using the hydrogel which can be applied to a bone defect region irrespective of the shape thereof, and to a method for manufacturing same.

Abstract: An ampoule for storing an implant capable of maintaining humidity includes: a container capable of airtight sealing at least momentarily or temporarily; a partition member which divides an accommodation space inside the container into two spaces, first and second spaces, and allows vaporized water molecules to be transported between the divided spaces; and a water molecule supply source which is accommodated in the first space of the two spaces divided by the partition member and supplies the vaporized water molecules. Therefore, the invention enables the construction of an environment which allows the hydrophilicity of the implant to be maintained for a long time, wherein the hydrophilicity is imparted to and protected from the surface of the implant or a coating layer formed on the surface of the implant.