Patents by Inventor Dag Rune Gjellesvik

Dag Rune Gjellesvik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of removing nucleic acid contamination in reverse transcription and amplification reactions
    Patent number: 9133447
    Abstract: The invention provides methods of removing nucleic acid contamination from reverse transcription reactions and hot-start PCR, wherein said hot-start PCR is a barrier hot-start PCR set up and/or involves a hot-start DNA polymerase, which methods comprise use of a DNase that is substantially irreversibly inactivated by heating at a temperature of about 50° C. for 5 minutes, and that is substantially specific for double stranded DNA. The invention further provides a DNase that is substantially irreversibly inactivated by heating at a temperature of about 50° C. for 5 minutes, and that is substantially specific for double stranded DNA, nucleic acids encoding said DNase and kits or compositions comprising said DNase or said nucleic acid.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: September 15, 2015
    Assignee: Biotec Pharmacon ASA
    Inventors: Olav Lanes, Morten Elde, Dag Rune Gjellesvik
  • Method of Removing Nucleic Acid Contamination in Reverse Transcription and Amplification Reactions
    Publication number: 20140093938
    Abstract: The invention provides methods of removing nucleic acid contamination from reverse transcription reactions and hot-start PCR, wherein said hot-start PCR is a barrier hot-start PCR set up and/or involves a hot-start DNA polymerase, which methods comprise use of a DNase that is substantially irreversibly inactivated by heating at a temperature of about 50° C. for 5 minutes, and that is substantially specific for double stranded DNA. The invention further provides a DNase that is substantially irreversibly inactivated by heating at a temperature of about 50° C. for 5 minutes, and that is substantially specific for double stranded DNA, nucleic acids encoding said DNase and kits or compositions comprising said DNase or said nucleic acid.
    Type: Application
    Filed: September 25, 2013
    Publication date: April 3, 2014
    Applicant: BIOTEC PHARMACON ASA
    Inventors: Olav Lanes, Morten Elde, Dag Rune Gjellesvik
  • Method of removing nucleic acid contamination in reverse transcription and amplification reactions
    Patent number: 8551753
    Abstract: The invention provides methods of removing nucleic acid contamination from reverse transcription reactions and hot-start PCR, wherein said hot-start PCR is a barrier hot-start PCR set up and/or involves a hot-start DNA polymerase, which methods comprise use of a DNase that is substantially irreversibly inactivated by heating at a temperature of about 50° C. for 5 minutes, and that is substantially specific for double stranded DNA. The invention further provides a DNase that is substantially irreversibly inactivated by heating at a temperature of about 50° C. for 5 minutes, and that is substantially specific for double stranded DNA, nucleic acids encoding said DNase and kits or compositions comprising said DNase or said nucleic acid.
    Type: Grant
    Filed: July 21, 2010
    Date of Patent: October 8, 2013
    Assignee: Biotec Pharmacon ASA
    Inventors: Olav Lanes, Morten Elde, Dag Rune Gjellesvik
  • Method of Removing Nucleic Acid Contamination in Reverse Transcription and Amplification Reactions
    Publication number: 20110020878
    Abstract: The invention provides methods of removing nucleic acid contamination from reverse transcription reactions and hot-start PCR, wherein said hot-start PCR is a barrier hot-start PCR set up and/or involves a hot-start DNA polymerase, which methods comprise use of a DNase that is substantially irreversibly inactivated by heating at a temperature of about 50° C. for 5 minutes, and that is substantially specific for double stranded DNA. The invention further provides a DNase that is substantially irreversibly inactivated by heating at a temperature of about 50° C. for 5 minutes, and that is substantially specific for double stranded DNA, nucleic acids encoding said DNase and kits or compositions comprising said DNase or said nucleic acid.
    Type: Application
    Filed: July 21, 2010
    Publication date: January 27, 2011
    Applicant: BIOTEC PHARMACON ASA
    Inventors: Olav Lanes, Morten Elde, Dag Rune Gjellesvik
  • COD URACIL-DNA GLYCOSYLASE, GENE CODING THEREFORE, RECOMBINANT DNA CONTAINING SAID GENE OR OPERATIVE PARTS THEREOF, A METHOD FOR PREPARING SAID PROTEIN AND THE USE OF SAID PROTEIN OR SAID OPERATIVE PARTS THEREOF IN MONITORING OR CONTROLLING PCR
    Patent number: 7037703
    Abstract: It is disclosed a novel enzyme present in cod liver, a DNA sequence encoding the enzyme or operative parts or biologically functional parts thereof, a novel recombinant DNA comprising the gene or the operative or biologically functional parts thereof, a method of preparing the enzyme from cod liver and from bacteria carrying the gene, the bacteria carrying the gene per se, and the use of the protein in monitoring and/or controlling PCR or related reaction systems.
    Type: Grant
    Filed: January 10, 2001
    Date of Patent: May 2, 2006
    Assignee: Biotec Pharmacon ASA
    Inventors: Olav Lanes, Nils Peder Willasen, Per Henrik Guddal, Dag Rune Gjellesvik
  • Cod uracil-DNA glycosylase, gene coding therefore, recombinant DNA containing said gene or operative parts thereof, a method for preparing said protein and the use of said protein or said operative parts thereof in monitoring or controlling PCR
    Publication number: 20020155573
    Abstract: It is disclosed a novel enzyme present in cod liver, a DNA sequence encoding the enzyme or operative parts or biologically functional parts thereof, a novel recombinant DNA comprising the gene or tho operative or biologically functional parts thereof, a method of preparing the enzyme from cod liver and from bacteria carrying the gene, the bacteria carrying the gene per se, and the use of the protein in monitoring and/or controlling PCR or related reaction systems.
    Type: Application
    Filed: January 10, 2001
    Publication date: October 24, 2002
    Applicant: BIOTEC ASA
    Inventors: Olav Lanes, Nils Peder Willasen, Per Henrik Guddal, Dag Rune Gjellesvik