Patents by Inventor Dagne L. Florine

Dagne L. Florine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment and prevention of oral mucositis with growth factors
    Patent number: 5102870
    Abstract: Methods are provided of preventing and treating chemotherapy or radiotherapy induced oral mucositis in a mammal by administering an effective dose of a growth factor, such as TGF-.alpha.. The growth factor may be used alone or in combination with other growth factors. Typically the effective dose is within the range of about 0.01-100 .mu.g/dose, administered 2-4 times daily.
    Type: Grant
    Filed: April 14, 1989
    Date of Patent: April 7, 1992
    Assignees: Schering AG, Virginia Commonwealth University
    Inventors: Dagne L. Florine, Thomas J. Smith
  • Peptides representing epitopic sites for the major HTLV-I envelope protein, antibodies thereto, and uses thereof
    Patent number: 5003043
    Abstract: The present invention discloses synthetic peptides and antibodies raised thereto wherein the synthetic peptides represent important epitopic sites recognized by the 0.5 .alpha. antibody, a human monoclonal antibody which can neutralize HTLV-I. Also, the uses of these peptides or antibodies thereto either alone or in combination with peptides representing the epitopic site for the predominant antibodies found in HTLV-I env seropositive sera as diagnostics, therapeutics and vaccines are disclosed.
    Type: Grant
    Filed: May 25, 1988
    Date of Patent: March 26, 1991
    Assignee: Triton Biosciences Inc.
    Inventors: Robert W. Akita, Dagne L. Florine, John S. Ralston