Patents by Inventor Dai-Wu Seol

Dai-Wu Seol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multi-Cistronic shRNA Expression Cassette for Suppressing Single or Multiple Target Genes
    Publication number: 20120142764
    Abstract: The present invention relates to one multi-cistronic shRNA for suppressing single or multiple target genes, and more particularly, to a multi-cistronic shRNA expression cassette, an expression vector comprising the multi-cistronic shRNA expression cassette, cells transduced with the multi-cistronic shRNA expression vector, a composite of the expression vector and a carrier, a method for suppressing various target genes, and a composition for suppressing target genes comprising the expression vector.
    Type: Application
    Filed: June 4, 2010
    Publication date: June 7, 2012
    Inventor: Dai-Wu Seol
  • DNA cassette for the production of secretable recombinant trimeric TRAIL proteins, tetracycline/ doxycycline-inducible adeno-associated virus vector, their combination and use in gene therapy
    Publication number: 20020128438
    Abstract: The present invention relates to the construction of a TRAIL DNA cassette for the production of a secretable trimeric rTRAIL, the development of pCMVdw vectors and pAAVdw vectors harboring a feed-forward amplification loop type Tet-On system that can be packaged into AAV particles, the preparation of a recombinant vectors by the combination of the TRAIL DNA cassette and the two vectors, and the treatment of diseases including cancer using such vectors.
    Type: Application
    Filed: July 6, 2001
    Publication date: September 12, 2002
    Inventors: Dai-Wu Seol, Timothy R. Billiar