Abstract: A toner conveyance device includes a downward passage, a reciprocating member disposed in the downward passage, to move in a vertical direction in which the downward passage extends, a conveyance passage communicating with a lower end of the downward passage and extending in a direction crossing the vertical direction, a conveyor to rotate in the conveyance passage around an axis extending along the conveyance passage to transport the toner, and a flexible member projecting from a bottom of the reciprocating member toward the conveyance passage. The flexible member extends in the axial direction of the conveyor and moves together with the reciprocating member. When the reciprocating member is at a lowest position, a lower end of the flexible member opposes a portion of the conveyor downstream from an upper end thereof in a rotation direction thereof.

Abstract: Provided is a scanning type image measuring apparatus capable of reducing an imaging time while suppressing an increase in power consumption. The scanning type image measuring apparatus includes an objective lens scanning mechanism for operating an objective lens in a first direction and a second direction perpendicular to the first direction, wherein, with respect to a resonance frequency related to a spring constant of a support member supporting a movable unit including the objective lens and a mass of the movable unit, the resonance frequency in the second direction is set to be higher than the resonance frequency in the first direction, and a scanning frequency of the objective lens in the second direction is set to be higher than the resonance frequency in the second direction.

Abstract: A device disposed opposing an image bearer includes a roller to rotate while contacting a surface of the image bearer, a rolling bearing fitted around a shaft located at an end of the roller in an axial direction of the roller, a frame to house the roller, and a bearing support removably attached to the frame. The rolling bearing includes an outer ring, an inner ring, and a rolling element disposed between the outer ring and the inner ring. The bearing support holds, from an outer-ring side, the rolling bearing interposed between the bearing support and the frame. The bearing support includes a receiving portion to contact the outer ring of the rolling bearing and bias the rolling bearing toward the frame in a direction in which the rolling bearing is interposed between the bearing support and the frame.

Abstract: The present invention relates to a compound which may be useful as an agent for the prophylaxis or treatment of cancer, hepatitis, hepatic fibrosis, fatty liver and the like.

Abstract: An electrostatic charge image developing toner includes toner particles each including an amorphous resin and a crystalline resin, wherein, when the toner particles are subjected to a measurement to determine an area ratio of the crystalline resin on a cross section of the toner particle before and after being heated at a temperature of 50° C. and a humidity of 50% RH for three days, a relationship between an area ratio a (%) of the crystalline resin on a cross section with respect to the toner particles before being heated, and an area ratio b (%) of the crystalline resin on the cross section with respect to the toner particles after being heated satisfies Expression (1): 0.9?a/b?1.0.

Abstract: A cleaning device, which is included in a process cartridge and an image forming apparatus, includes a cleaning blade configured to remove a material attached to a surface of an image bearer, a cleaning case configured to contain the material removed by the cleaning blade, and a removed material receiver configured to receive the material failed to enter into the cleaning case when the material is removed by the cleaning blade, the removed material receiver having a first range at both ends in a width direction of the cleaning blade and a second range at a center in the width direction of the cleaning blade. A volume per unit length in a width direction of the first range is greater than a volume per unit length in a width direction of the second range.

Abstract: Provided is a bicyclic compound having an acetyl-CoA carboxylase inhibitory action. A compound represented by the formula: wherein each symbol is as described in the DESCRIPTION, or a salt thereof has an acetyl-CoA carboxylase inhibitory action, is useful for the prophylaxis or treatment of cancer, inflammatory diseases and the like, and has superior efficacy.

Abstract: An image forming apparatus includes an image bearer to bear a toner image, a lubricant supply roller to supply lubricant to a surface of the image bearer, a rotation speed changer to change a rotation speed of the lubricant supply roller, and a controller to control the rotation speed changer to change the rotation speed of the lubricant supply roller to a target speed based on a predetermined condition. The controller is configured to control the rotation speed changer to avoid a predetermined speed range.

Abstract: A cleaning device includes a cleaning blade disposed in contact with a rotator, a toner collecting section disposed along the rotator and the cleaning blade and includes a groove extending in an axial direction of the rotator, a conveyor disposed in the groove, and an agitator disposed on a side of a rim of the groove. The conveyor rotates to convey the toner in a longitudinal direction of the groove. The agitator vibrates through contact with the conveyor and includes comb-tooth portions lined in a comb shape in the longitudinal direction of the groove, and bent portions, each of which is bent from an end of one of the comb-tooth portions. The comb-tooth portions contact a circumference of the conveyor to vibrate. The bent portions are lined at intervals smaller than intervals on a base side of the comb-tooth portions.

Abstract: A toner conveyance device includes a downward passage, a reciprocating member disposed in the downward passage, to move in a vertical direction in which the downward passage extends, a conveyance passage communicating with a lower end of the downward passage and extending in a direction crossing the vertical direction, a conveyor to rotate in the conveyance passage around an axis extending along the conveyance passage to transport the toner, and a flexible member projecting from a bottom of the reciprocating member toward the conveyance passage. The flexible member extends in the axial direction of the conveyor and moves together with the reciprocating member. When the reciprocating member is at a lowest position, a lower end of the flexible member opposes a portion of the conveyor downstream from an upper end thereof in a rotation direction thereof.

Abstract: The present invention provides a compound having a lysine specific demethylase 1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, Alzheimer's disease, Parkinson's disease or Huntington's disease, and the like. The present invention relates to a compound represented by the formula wherein A is a hydrocarbon group optionally having substituent(s), or a heterocyclic group optionally having substituent(s); B is a benzene ring optionally having further substituent(s); R1, R2 and R3 are each independently a hydrogen atom, a hydrocarbon group optionally having substituent(s), or a heterocyclic group optionally having substituent(s); A and R1 are optionally bonded to each other to form, together with the adjacent nitrogen atom, a cyclic group optionally having substituent(s); and R2 and R3 are optionally bonded to each other to form, together with the adjacent nitrogen atom, a cyclic group optionally having substituent(s), or a salt thereof.

Abstract: A method of preparing silica composite particles includes preparing an alkali catalyst solution containing an alkali catalyst at a concentration of from 0.6 mol/L to 0.85 mol/L, in a solvent containing alcohol; and supplying, into the alkali catalyst solution, (i) a mixed solution of tetraalkoxysilane and an organic titanium compound in which an organic group is coupled to a titanium atom through oxygen, and (ii) an alkali catalyst. The mixed solution is supplied at a supply amount of from 0.001 mol/(mol·min) to 0.01 mol/(mol·min) relative to the alcohol, and the alkali catalyst is supplied at a supply amount of from 0.1 mol to 0.4 mol, relative to 1 mol of a total supply amount of the tetraalkoxysilane and the organic titanium compound supplied per one minute.

Abstract: A toner conveyance device includes a toner conveyance path through which toner is transported. The toner conveyance path includes a flexible portion, a toner conveyor inside the conveyance path to convey the toner, and a restrictor outside the toner conveyance path to restrict deformation of the toner conveyance path.

Abstract: An image forming apparatus includes an image bearer; a charger to charge a surface of the image bearer; an exposure device to expose the surface of the image bearer and form an electrostatic latent image on the image bearer; a developing device to adhere electrically charged toner to the electrostatic latent image on the image bearer, to thereby form a toner image; a microprocessor to control rotation of the image bearer; and a sensor to detect temperature and humidity. In a state of suspended rotation of the image bearer, the microprocessor controls the image bearer to rotate a predetermined amount at a predetermined interval and determines whether a rotation operation of the image bearer is to be performed, based on a detection result of the sensor.

Abstract: The present invention provides a compound having a lysine-specific demethylase 1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for cancer, and central nervous system diseases, and the like.

Abstract: Provided is a compact, low-cost optical measuring apparatus capable of acquiring an image of a target to be measured without moving a mirror or using a wavelength-scanning light source or beam splitter. A laser beam emitted from a light source is split into first and second beams, and the first beam is focused as a signal beam onto the target by a lens for irradiation purposes, while the second beam is reflected as a reference beam by a mirror without irradiating the target. Then, a signal beam reflected by or scattered by the target is multiplexed with the reference beam and then enters interference optics, whereby three or more interference beams with different phases are generated and detected by photodetectors. Then, the detection signals are operated by a signal processing unit. During the measurement, the focus position of the first beam is moved at least in the optical axis direction.

Abstract: An optical measurement apparatus has a light source that emits a laser beam that is branched into signal light and reference light. An objective lens condenses the signal light on a measurement target to cause the measurement target to be irradiated; and a condensing position of the signal light is scanned in an optical axis direction. An interference optical system combines the signal light reflected or scattered from the measurement target with the reference light, and generates a plurality of interfering light beams having phase relationships different from one another that are detected by photodetectors. The detection signals are output as electrical signals; and a signal processing unit performs a predetermined arithmetic operation on the plurality of detection signals. The signal processing unit subtracts reflection light components from a predetermined portion of the measurement target from the plurality of detection signals or signals generated using the detection signals.

Abstract: A lubricant applicator includes a lubricant, a supply member contactable against the lubricant to supply the lubricant to a target, and a lubricant gauge to detect whether an amount of lubricant remaining is less than a threshold value. The lubricant gauge includes a rotary member rotatable about a shaft, a pressing member to press and rotate the rotary member as the lubricant is consumed, a contact part of the rotary member pressed by the pressing member, and a detection part of the rotary member opposite to the contact part across the shaft of the rotary member.

Abstract: A device disposed opposing an image bearer includes a roller to rotate while contacting a surface of the image bearer, a rolling bearing fitted around a shaft located at an end of the roller in an axial direction of the roller, a frame to house the roller, and a bearing support removably attached to the frame. The rolling bearing includes an outer ring, an inner ring, and a rolling element disposed between the outer ring and the inner ring. The bearing support holds, from an outer-ring side, the rolling bearing interposed between the bearing support and the frame. The bearing support includes a receiving portion to contact the outer ring of the rolling bearing and bias the rolling bearing toward the frame in a direction in which the rolling bearing is interposed between the bearing support and the frame.

Abstract: A clear image of a measurement target in optical coherence tomography (OCT) is obtained while suppressing influence of reflected light from a specific portion. Included are a laser beam source, a beam splitter that splits a laser beam into a signal beam and reference beam; an objective lens that focuses the signal beam onto a measurement target in a container, a unit that moves the signal beam focus position, an objective lens that focuses the reference beam, a reflecting mirror, a flat plate arranged between the objective lens and reflecting mirror, and interference optics that combine the signal beam reflected by the measurement target with the reference beam reflected by the reflecting mirror and having passed through the objective lens. Three or more interference beams with different phases, and photodetectors that detect the interference beams are generated, and two of the objective lenses are the same lenses.