Patents by Inventor Damián GARCÍA OLMO

Damián GARCÍA OLMO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MESENCHYMAL STEM CELLS CO-EXPRESSING CXCR4 AND IL-10 AND USES THEREOF
    Publication number: 20230398152
    Abstract: The present invention refers to mesenchymal stem cells (MSCs) characterized in that they are transduced with an integrative expression vector in order to stably co-express the chemokine receptor type 4 CXCR4 and the interleukin EL-10. The present invention also refers to the use of said MSCs as a medicament, particularly in the treatment of inflammatory and/or autoimmune diseases.
    Type: Application
    Filed: September 7, 2021
    Publication date: December 14, 2023
    Inventors: Rosario Hervas-Salcedo, Damian García-olmo, Mariano García-Arranz, Miriam Hernando Rodríguez, Juan Antonio Bueren Roncero, Rosa Yáñez González, Maria Femández García, Mercedes López Santalla, Marina Immaculada Garin Ferreira
  • Use of adipose tissue-derived stromal stem cells in treating fistula
    Patent number: 11672831
    Abstract: Provided herein are novel methods and composition utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: June 13, 2023
    Assignees: Takeda Pharmaceutical Company Limited, Universidad Autónoma de Madrid
    Inventors: María Gema Fernández Miguel, Manuel Ángel González De La Peña, Rosa Ana García Castro, Mariano García Arranz, Damián García Olmo
  • Use of adipose tissue-derived stromal stem cells in treating fistula
    Patent number: 11660318
    Abstract: Provided herein are novel methods and composition utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: May 30, 2023
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: María Gema Fernández Miguel, Manuel Ángel González De La Pena, Rosa Ana García Castro, Mariano García Arranz, Damián García Olmo
  • Biomaterial for suturing
    Patent number: 11253632
    Abstract: A biomaterial for suturing comprising a physiologically compatible support material coated with a cellular population with proliferative and/or differentiation capacity, characteristics which facilitate the regeneration of the sutured tissue. This biomaterial for suturing not only brings together the two edges of an open wound, but also contributes actively to the healing process, thereby accelerating the tissue repair process. Also disclosed are methods for making the biomaterial and methods for using the biomaterials in therapy.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: February 22, 2022
    Assignees: TIGENIX, S.A.U., Universidad Autonoma de Madrid
    Inventors: Damian Garcia-Olmo, Gema Fernandez Miguel, Manuel A. Gonzalez De La Pena, Mariano G. Arranz
  • CHEMICAL SCALPEL
    Publication number: 20220047687
    Abstract: The present invention relates to a liquid collagenase solution which will generate the pre-conditioning of the tissues covering peritoneal tumors by means of washing with said solution for a predetermined time and at a predetermined concentration for use as cytotoxic drug-enhancing or adjuvant treatment in the treatment of solid peritoneal tumors. Throughout the present invention, said solution will be used for administration to or for irrigating the tumor directly at a concentration and for a time such that it causes thinning of the mesothelial layer covering the intestinal tract without the involvement of intermediate or internal layers.
    Type: Application
    Filed: February 19, 2020
    Publication date: February 17, 2022
    Inventors: Héctor GUADALAJARA LABAJO, Mariano GARCIA ARRANZ, Damián GARCIA OLMO, Javier Jesús BARAMBIO BUENDÍA, Delia CORTÉS GUIRAL, Susana OLMEDILLAS LÓPEZ, Mª Luz VEGA CLEMENTE
  • Use of adipose tissue-derived stromal stem cells in treating fistula
    Patent number: 10780132
    Abstract: Provided herein are novel methods and compositions utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: September 22, 2020
    Assignees: TiGenix, S.A.U., Universidad Autónoma de Madrid
    Inventors: María Gema Fernández Miguel, Manuel Ángel González De La Peña, Rosa Ana García Castro, Mariano García Arranz, Damián García Olmo
  • Use of adipose tissue-derived stromal stem cells in treating fistula
    Patent number: 10758575
    Abstract: Provided herein are novel methods and composition utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: September 1, 2020
    Assignees: TiGenix, S.A.U., UNIVERSIDAD AUTÓNOMA DE MADRID
    Inventors: María Gema Fernández Miguel, Manuel Ángel González De La Peña, Rosa Ana García Castro, Mariano García Arranz, Damián García Olmo
  • Identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue
    Patent number: 10729726
    Abstract: Identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue. This invention relates to the identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue. Specifically, it relates to an adult multipotent cell or a cell population or composition comprising the cell, isolated from non-osteochondral mesenchymal tissue, characterized in that it is positive for the following markers: CD9, CD10, CD13, CD29, CD44, CD49A, CD51, CD54, CD55, CD58, CD59, CD90 and CD105 and because it lacks expression of the following markers: CD11b, CD14, CD15, CD16, CD31, CD34, CD45, CD49f, CD102, CD104, CD106 and CD133.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: August 4, 2020
    Assignees: TIGENIX, S.A.U., UNIVERSIDAD AUTÓNOMA DE MADRID
    Inventors: Rosa Ana García Castro, María Gema Fernández Miguel, Mariano García Arranz, Manuel Angel González De La Peña, Damián García Olmo
  • USE OF ADIPOSE TISSUE-DERIVED STROMAL STEM CELLS IN TREATING FISTULA
    Publication number: 20200206274
    Abstract: Provided herein are novel methods and compositions utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Application
    Filed: December 20, 2019
    Publication date: July 2, 2020
    Applicants: TiGenix, S.A.U., Universidad Autonoma de Madrid
    Inventors: María Gema FERNÁNDEZ MIGUEL, Manuel Angel GONZALEZ DE LA PENA, Rosa Ana GARCIA CASTRO, Mariano GARCIA ARRANZ, Damian GARCIA-OLMO
  • Biomaterial for Suturing
    Publication number: 20200101199
    Abstract: A biomaterial for suturing comprising a physiologically compatible support material coated with a cellular population with proliferative and/or differentiation capacity, characteristics which facilitate the regeneration of the sutured tissue. This biomaterial for suturing not only brings together the two edges of an open wound, but also contributes actively to the healing process, thereby accelerating the tissue repair process. Also disclosed are methods for making the biomaterial and methods for using the biomaterials in therapy.
    Type: Application
    Filed: June 10, 2019
    Publication date: April 2, 2020
    Inventors: Damian Garcia-Olmo, Maria Gema F. Miguel, Manuel A. Gonzalez De La Pena, Mariano G. Arranz
  • Use of adipose tissue-derived stromal stem cells in treating fistula
    Patent number: 10548924
    Abstract: Provided herein are novel methods and compositions utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: February 4, 2020
    Assignees: TIGENIX, S.A.U., UNIVERSIDAD AUTONOMA DE MADRID
    Inventors: Maria Gema Fernandez Miguel, Manuel Angel Gonzalez De La Pena, Rosa Ana Garcia Castro, Mariano Garcia Arranz, Damian Garcia-Olmo
  • USE OF ADIPOSE TISSUE-DERIVED STROMAL STEM CELLS IN TREATING FISTULA
    Publication number: 20190269737
    Abstract: Provided herein are novel methods and composition utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Application
    Filed: February 1, 2019
    Publication date: September 5, 2019
    Applicants: TiGenix, S.A.U., Universidad Autónoma de Madrid
    Inventors: María Gema FERNÁNDEZ MIGUEL, Manuel Ángel GONZÁLEZ DE LA PEÑA, Rosa Ana GARCÍA CASTRO, Mariano GARCÍA ARRANZ, Damián GARCÍA OLMO
  • IDENTIFICATION AND ISOLATION OF MULTIPOTENT CELLS FROM NON-OSTEOCHONDRAL MESENCHYMAL TISSUE
    Publication number: 20170296585
    Abstract: Identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue. This invention relates to the identification and isolation of multipotent cells from non-osteochondral mesenchymal tissue. Specifically, it relates to an adult multipotent cell or a cell population or composition comprising said cell, isolated from non-osteochondral mesenchymal tissue, characterized in that it is positive for the following markers: CD9, CD10, CD13, CD29, CD44, CD49A, CD51, CD54, CD55, CD58, CD59, CD90 and CD105 and because it lacks expression of the following markers: CD11b, CD14, CD15, CD16, CD31, CD34, CD45, CD49f, CD102, CD104, CD106 and CD133.
    Type: Application
    Filed: August 24, 2015
    Publication date: October 19, 2017
    Inventors: Rosa Ana GARCÍA CASTRO, María Gema FERNÁNDEZ MIGUEL, Mariano GARCÍA ARRANZ, Manuel Angel GONZÁLEZ DE LA PEÑA, Damián GARCÍA OLMO
  • USE OF ADIPOSE TISSUE-DERIVED STROMAL STEM CELLS IN TREATING FISTULA
    Publication number: 20170209496
    Abstract: Provided herein are novel methods and composition utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Application
    Filed: March 20, 2017
    Publication date: July 27, 2017
    Applicants: TiGenix, S.A.U., Universidad Autónoma de Madrid
    Inventors: María Gema FERNÁNDEZ MIGUEL, Manuel Ángel GONZÁLEZ DE LA PEÑA, Rosa Ana GARCÍA CASTRO, Mariano GARCÍA ARRANZ, Damián GARCÍA OLMO
  • USE OF ADIPOSE TISSUE-DERIVED STROMAL STEM CELLS IN TREATING FISTULA
    Publication number: 20170189452
    Abstract: Provided herein are novel methods and compositions utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Application
    Filed: March 23, 2017
    Publication date: July 6, 2017
    Applicants: TiGenix, S.A.U., Universidad Autónoma de Madrid
    Inventors: María Gema FERNÁNDEZ MIGUEL, Manuel Ángel GONZÁLEZ DE LA PEÑA, Rosa Ana GARCÍA CASTRO, Mariano GARCÍA ARRANZ, Damián GARCÍA OLMO
  • USE OF ADIPOSE TISSUE-DERIVED STROMAL STEM CELLS IN TREATING FISTULA
    Publication number: 20170189451
    Abstract: Provided herein are novel methods and composition utilizing adipose tissue-derived stromal stern cells for treating fistulae.
    Type: Application
    Filed: March 20, 2017
    Publication date: July 6, 2017
    Applicants: TiGenix, S.A.U., Universidad Autónoma de Madrid
    Inventors: María Gema FERNÁNDEZ MIGUEL, Manuel Ángel GONZÁLEZ DE LA PEÑA, Rosa Ana GARCÍA CASTRO, Mariano GARCÍA ARRANZ, Damián GARCÍA OLMO
  • Method for blocking tumour growth
    Patent number: 9555075
    Abstract: The present invention concerns a pharmaceutical composition comprising virtosomes isolated from non-dividing cells or the medium in which the cells are grown, for use in the inhibition of tumor growth and/or prevention of metastases.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: January 31, 2017
    Assignee: THE FOUNDATION FOR BIOMEDICAL RESEARCH OF LA PAZ UNIVERSITY HOSPITAL (FIBHULP)
    Inventors: Damián Garcia-Olmo, Mariano Garcia-Arranz, Luz Vega Clemente, Peter Brian Gahan, Maurice Stroun
  • Use of adipose tissue-derived stromal stem cells in treating fistula
    Patent number: 8999709
    Abstract: Provided herein are novel methods and compositions utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: April 7, 2015
    Assignees: Tigenix, S.A.U., Universidad Autonoma de Madrid
    Inventors: María Gema Fernández Miguel, Manuel Angel González de la Peña, Rosa Ana García Castro, Mariano García Arranz, Damián García Olmo
  • METHOD FOR BLOCKING TUMOUR GROWTH
    Publication number: 20150071986
    Abstract: The present invention concerns a pharmaceutical composition comprising virtosomes isolated from non-dividing cells or the medium in which the cells are grown, for use in the inhibition of tumour growth and/or prevention of metastases.
    Type: Application
    Filed: May 29, 2014
    Publication date: March 12, 2015
    Applicant: The Foundation for Biomedical Research of La Paz University Hospital (FIBHULP)
    Inventors: Damián GARCIA-OLMO, Mariano Garcia-Arranz, Luz Vega Clemente, Peter Brian Gahan, Maurice Stroun
  • USE OF ADIPOSE TISSUE-DERIVED STROMAL STEM CELLS IN TREATING FISTULA
    Publication number: 20150065948
    Abstract: Provided herein are novel methods and composition utilizing adipose tissue-derived stromal stem cells for treating fistulae.
    Type: Application
    Filed: November 11, 2014
    Publication date: March 5, 2015
    Inventors: María Gema FERNÁNDEZ MIGUEL, Manuel Ángel GONZÁLEZ DE LA PEÑA, Rosa Ana GARCÍA CASTRO, Mariano GARCÍA ARRANZ, Damián GARCÍA OLMO