Abstract: The present application is related to deuterated compounds which are novel neurotrophin mimetics. The application also discloses the treatment of disorders involving degradation or dysfunction of cells expressing p75 in a mammal by administering an effective amount of such deuterated compounds.

Abstract: The present application is related to deuterated compounds which are novel neurotrophin mimetics. The application also discloses the treatment of disorders involving degradation or dysfunction of cells expressing p75 in a mammal by administering an effective amount of such deuterated compounds.

Abstract: The invention relates to a novel nine step process for synthesizing PQQ (methoxatin). This process is efficient and reliably provides PQQ in excellent purity and high yield.

Abstract: By this invention, low calorie fat compositions comprising the use of acylated glycerides are provided. Of particular interest is the use of triglyceride compositions having a at least one acylated fatty acid. Preferably, the acylated fatty acid has a melting temperature above 40° C. The acylated glyceride compositions find use as low calorie fat ingredients in food compositions. The low calorie fat compositions of the present invention demonstrate a caloric value of less than 6.5 kcal/g. Such low calorie fat compositions find use in the preparation of food compositions wherein at least a portion of the fat ingredients have been replaced with a acylated glyceride compositions of the present invention.

Abstract: By this invention, low calorie fat compositions comprising the use of wax esters are provided. Of particular interest is the use of wax ester compositions having a long chain hydrocarbon and a medium chain hydrocarbon. Preferably, the long chain hydrocarbon group is a saturated long chain hydrocarbon. The wax ester compositions find use as low calorie fat ingredients in food compositions. The low calorie fat compositions of the present invention demonstrate a caloric value of less than 6 kcal/g. Such low calorie fat compositions find use in the preparation of food compositions wherein at least a portion of the fat ingredients have been replaced with a wax ester composition of the present invention.

Abstract: By this invention, low calorie fat compositions comprising the use of hydroxy triglycerides are provided. Of particular interest is the use of triglyceride compositions having a at least one hydroxy fatty acid. Preferably, the hydroxy fatty acid has a melting temperature above 40° C. The hydroxy triglyceride compositions find use as low calorie fat ingredients in food compositions. The low calorie fat compositions of the present invention demonstrate a caloric value of less than 5.0 kcal/g. Such low calorie fat compositions find use in the preparation of food compositions wherein at least a portion of the fat ingredients have been replaced with a hydroxy triglyceride composition of the present invention.

Abstract: By this invention, low calorie fat compositions comprising the use of acylated glycerides are provided. Of particular interest is the use of triglyceride compositions having a at least one acylated fatty acid. Preferably, the acylated fatty acid has a melting temperature above 40° C. The acylated glyceride compositions find use as low calorie fat ingredients in food compositions. The low calorie fat compositions of the present invention demonstrate a caloric value of less than 6.5 kcal/g. Such low calorie fat compositions find use in the preparation of food compositions wherein at least a portion of the fat ingredients have been replaced with a acylated glyceride compositions of the present invention.