Abstract: Disclosed herein are high Tm RNA nanostructures that can be composed of one or more modules or motifs to build RNA nanostructures with or without layers. The RNA nanostructures can have a core domain and three or more double-stranded arms and formulations thereof to conjugate high copy numbers of therapeutics, pH responsive or enzyme cleavable drug cargo. Also described herein is a design strategy for generation of synthetic RNA oligonucleotides that can self assemble into highly thermostable RNA structures. Also described herein are uses of the RNA nanostructures described herein.

Abstract: The present disclosure provides a preparation method for hydrothermal synthesis of fly ash silicate aggregate including: mixing sodium metasilicate, potassium hydroxide, and inorganic-organic hybrid excitation monomer as raw materials to obtain an inorganic-organic composite activator; preparing a silicate aggregate raw material, mixing measured fly ash, carbide slag, quicklime, and vitrified micro bubble by mass, adding the inorganic-organic composite activator and continue stirring to produce a mixture; forming a ball disc, wetting an expanded perlite that forms a core of the ball by spraying water, adding a prepared mixture, spraying water while adding, standing and curing, performing a maturation and activation treatment in an autoclave, undergoing a silicon calcium reaction for a hydrothermal synthesis to obtain the silicate aggregates.

Abstract: A flood control device for detecting discharge from a release outlet, comprising a receptacle having an upper opening, a bottom, and a drain hole; a first water level sensor configured to be triggered by water reaching a first level; a second water level sensor configured to be triggered by water reaching a second level, wherein the first water level sensor is closer to the bottom of the receptacle than the second water level sensor, wherein triggering the first water level sensor represents a low flow signal, and triggering both the first water level sensor and the second water level sensor represents a high flow signal. The low flow signal can be used to trigger a warning, and the high flow signal can be used to trigger automatic shutoff and/or shutoff alarm.

Abstract: Embodiments relate to a system configured to provide communication alerts for a backflow preventer. The communication alerts can be alerts regarding tampering with and/or improper operation of the backflow preventer or a component of the backflow preventer. The system can further be configured to record and track performance measures of at least one backflow preventer within a system of backflow preventers. In some embodiments, a first network of backflow preventers can be established to communicate with a second network so that communication alerts can be disseminated to appropriate individuals for enhanced tracking, monitoring, and/or maintenance of the backflow preventers. Some embodiments of the system can include transmitting a command signal from a computer device of the second network to the backflow preventer to control aspects or components of the backflow preventer.

Abstract: A sea water cooling system including a first fluid cooling loop coupled to a first side of a heat exchanger and to a thermal load, a second fluid cooling loop coupled to a second side of the heat exchanger and including a pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the pump, wherein the controller is configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the pump based on the monitored temperature to achieve a predetermined temperature in the first fluid cooling loop. The system may be selectively operable in one of a plurality of operating modes, wherein in a first operating mode the pump operates based entirely on cooling demands of the thermal load, and in a second operating mode the pump operates to maintain a fluid pressure above a predefined pressure.

Abstract: A sea water cooling system including a first fluid cooling loop coupled to a first side of a heat exchanger and to a thermal load, a second fluid cooling loop coupled to a second side of the heat exchanger and including a pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the pump, wherein the controller is configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the pump based on the monitored temperature to achieve a predetermined temperature in the first fluid cooling loop. The system may be selectively operable in one of a plurality of operating modes, wherein in a first operating mode the pump operates based entirely on cooling demands of the thermal load, and in a second operating mode the pump operates to maintain a fluid pressure above a predefined pressure.

Abstract: A system and method for monitoring and controlling a pump includes defining processing targets, deriving a first actuator control signal Yc from the processing targets, and deriving actual operating parameters. Additionally, the actual operating parameters are compared to predefined system and pump limits to determine a second actuator control signal Y?c, the actual operating parameters are compared to predefined fluid limits to determine a third actuator control signal Y?c, the actual operating parameters are compared to predefined normal processing limits to determine a fourth actuator control signal Y??c, and the actual operating parameters are compared to at least one predefined abnormal processing limit to determine a fifth actuator control signal Y??c. The most conservative actuator control signal is then determined, and the pump is driven in accordance with the most conservative actuator control signal.

Abstract: A seawater cooling system adapted to mitigate salt crystallization in a seawater cooling loop. The system may include a pump operatively connected to the cooling loop and configured to pump seawater through the cooling loop, a temperature sensor operatively connected to the cooling loop and configured to monitor a temperature of the seawater in the cooling loop, and a controller operatively connected to the temperature sensor and to the pump, the controller configured to issue a warning and to increase a speed of the pump if it is determined that the monitored temperature of the seawater exceeds a predetermined threshold temperature.

Abstract: An intelligent sea water cooling system including a first fluid cooling loop coupled to a first side of a heat exchanger and to a thermal load, a second fluid cooling loop coupled to a second side of the heat exchanger, a pump for circulating fluid through the second fluid cooling loop, and a controller connected to the pump. The controller may monitor a temperature in the first fluid cooling loop and may adjust a speed of the pump to keep the temperature within a preferred operating range. If the speed of the pump is reduced to a predefined minimum pressure pump speed, the controller may start a timer t1 having a predefined duration. If the timer t1 expires and the temperature has not increased relative to when the timer t1 was started, the controller may reduce the speed of the pump below the minimum pressure pump speed.

Abstract: A seawater cooling system adapted to mitigate salt crystallization in a seawater cooling loop. The system may include a pump operatively connected to the cooling loop and configured to pump seawater through the cooling loop, a temperature sensor operatively connected to the cooling loop and configured to monitor a temperature of the seawater in the cooling loop, and a controller operatively connected to the temperature sensor and to the pump, the controller configured to issue a warning and to increase a speed of the pump if it is determined that the monitored temperature of the seawater exceeds a predetermined threshold temperature.

Abstract: A sea water cooling system including a first fluid cooling loop coupled to a first side of a heat exchanger and to a thermal load, a second fluid cooling loop coupled to a second side of the heat exchanger and including a pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the pump, wherein the controller is configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the pump based on the monitored temperature to achieve a predetermined temperature in the first fluid cooling loop. The system may be selectively operable in one of a plurality of operating modes, wherein in a first operating mode the pump operates based entirely on cooling demands of the thermal load, and in a second operating mode the pump operates to maintain a fluid pressure above a predefined pressure.

Abstract: A sea water cooling system including a first fluid cooling loop coupled to a first side of a heat exchanger and to a thermal load, a second fluid cooling loop coupled to a second side of the heat exchanger and including a pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the pump, wherein the controller is configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the pump based on the monitored temperature to achieve a predetermined temperature in the first fluid cooling loop. The system may be selectively operable in one of a plurality of operating modes, wherein in a first operating mode the pump operates based entirely on cooling demands of the thermal load, and in a second operating mode the pump operates to maintain a fluid pressure above a predefined pressure.

Abstract: A sea water cooling system including a first fluid cooling loop coupled to a first side of a heat exchanger and to a thermal load, a second fluid cooling loop coupled to a second side of the heat exchanger and including a pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the pump, wherein the controller is configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the pump based on the monitored temperature to achieve a predetermined temperature in the first fluid cooling loop. The system may be selectively operable in one of a plurality of operating modes accordance, wherein in a first operating mode the pump is operated based entirely on cooling demands of the thermal load, and in a second operating mode the pump is operated to maintain a fluid pressure above a predefined pressure.

Abstract: An intelligent sea water cooling system including a first fluid cooling loop coupled to a first side of a heat exchanger and to a thermal load, a second fluid cooling loop coupled to a second side of the heat exchanger, a pump for circulating fluid through the second fluid cooling loop, and a controller connected to the pump. The controller may monitor a temperature in the first fluid cooling loop and may adjust a speed of the pump to keep the temperature within a preferred operating range. If the speed of the pump is reduced to a predefined minimum pressure pump speed, the controller may start a timer t1 having a predefined duration. If the timer t1 expires and the temperature has not increased relative to when the timer t1 was started, the controller may reduce the speed of the pump below the minimum pressure pump speed.

Abstract: An intelligent sea water cooling system including a first fluid cooling loop coupled to a heat exchanger, a second fluid cooling loop coupled to the heat exchanger and including a fluid pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the fluid pump. The controller may be configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the fluid pump based on the monitored temperature in order to achieve a desired temperature in the first fluid cooling loop.

Abstract: A seawater cooling system adapted to mitigate salt crystallization in a seawater cooling loop. The system may include a pump operatively connected to the cooling loop and configured to pump seawater through the cooling loop, a temperature sensor operatively connected to the cooling loop and configured to monitor a temperature of the seawater in the cooling loop, and a controller operatively connected to the temperature sensor and to the pump, the controller configured to issue a warning and to increase a speed of the pump if it is determined that the monitored temperature of the seawater exceeds a predetermined threshold temperature.

Abstract: A system and method are disclosed for monitoring and controlling a positive displacement pump using readings obtained from a plurality of pressure sensors. The pressure sensors may be mounted at the suction, discharge and interstage regions of the pump. Signals from the pressure sensors are compared to obtain a ratio that is used to predict whether a cavitation condition exists within the pump. The ratio can be compared to user provided limits to change an operating characteristic of the pump to reduce predicted cavitation. The pump may be stopped, or pump speed changed, when the ratio is less than a predetermined value. In some embodiments, historical information regarding the ratio may be used to obtain standard deviation information which may then be used to predict whether gas bubbles are passing through the pump. Other embodiments are described and claimed.

Abstract: An intelligent sea water cooling system including a first fluid cooling loop coupled to a heat exchanger, a second fluid cooling loop coupled to the heat exchanger and including a fluid pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the fluid pump. The controller may be configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the fluid pump based on the monitored temperature in order to achieve a desired temperature in the first fluid cooling loop.

Abstract: A sea water cooling system including a first fluid cooling loop coupled to a first side of a heat exchanger and to a thermal load, a second fluid cooling loop coupled to a second side of the heat exchanger and including a pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the pump, wherein the controller is configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the pump based on the monitored temperature to achieve a predetermined temperature in the first fluid cooling loop. The system may be selectively operable in one of a plurality of operating modes accordance, wherein in a first operating mode the pump is operated based entirely on cooling demands of the thermal load, and in a second operating mode the pump is operated to maintain a fluid pressure above a predefined pressure.

Abstract: Provided are a method and device for implementing data redundancy. The method includes: a storage strategy identifier of data to be stored is acquired; and the data to be stored is stored in a storage manner corresponding to the storage strategy identifier, wherein the storage strategy identifier is used for indicating the data to be stored is stored in at least one of the following storage manners: a copy redundancy processing manner and an eraser encoding and decoding processing manner. The problem of incapability of ensuring a higher storage space utilization rate in the related art is solved, so that the security and reliability of the data are ensured, meanwhile, the utilization rate of a storage space is increased, and data redundancy implementation flexibility is improved.