Patents by Inventor Danica Grujic
Danica Grujic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220378886Abstract: Disclosed are methods and compositions which can be used to treat diseases or disorders associated with an elevated amount of oxalate, including, for example, hyperoxaluria, in particular enteric hyperoxaluria.Type: ApplicationFiled: November 6, 2020Publication date: December 1, 2022Inventors: Danica Grujic, Kristine E. Bernard, Annamaria T. Kausz, Zhiqun Zhang
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Publication number: 20220133865Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: ApplicationFiled: June 17, 2021Publication date: May 5, 2022Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
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Patent number: 11077238Abstract: Compositions of peritoneal dialysis solutions and metabolizing enzymes, and their uses to treat disorders associated with elevated levels of metabolites are disclosed. Animal models of hyperoxalemia are also disclosed.Type: GrantFiled: June 6, 2014Date of Patent: August 3, 2021Assignee: Allena Pharmaceuticals, Inc.Inventors: Alexey Margolin, Danica Grujic, Stefan Pierzynowski
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Patent number: 10815461Abstract: Disclosed are recombinant mutant Candida utilis uricase enzymes with improved pancreatin stability and/or activity, compositions containing such uricase enzymes, which can be used, among other things, to treat diseases or disorders associated with an elevated amount of uric acid, including, for example, hyperuricemia, hyperuricosuria, and gout.Type: GrantFiled: November 5, 2019Date of Patent: October 27, 2020Assignee: Allena Pharmaceuticals, Inc.Inventors: Aditi R. Deshpande, Danica Grujic, Sridhar Govindarajan, Mark Welch
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Publication number: 20200308534Abstract: Disclosed are recombinant mutant Candida utilis uricase enzymes with improved pancreatin stability and/or activity, compositions containing such uricase enzymes, which can be used, among other things, to treat diseases or disorders associated with an elevated amount of uric acid, including, for example, hyperuricemia, hyperuricosuria, and gout.Type: ApplicationFiled: July 6, 2018Publication date: October 1, 2020Applicant: Allena Pharmaceuticals, Inc.Inventors: Aditi R. DESHPANDE, Danica GRUJIC, Sridhar GOVINDARAJAN, Mark WELCH
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Publication number: 20200129599Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: ApplicationFiled: June 19, 2019Publication date: April 30, 2020Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
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Publication number: 20200071681Abstract: Disclosed are recombinant mutant Candida utilis uricase enzymes with improved pancreatin stability and/or activity, compositions containing such uricase enzymes, which can be used, among other things, to treat diseases or disorders associated with an elevated amount of uric acid, including, for example, hyperuricemia, hyperuricosuria, and gout.Type: ApplicationFiled: November 5, 2019Publication date: March 5, 2020Inventors: Aditi R. Deshpande, Danica Grujic, Sridhar Govindarajan, Mark Welch
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Patent number: 10369203Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: GrantFiled: October 23, 2017Date of Patent: August 6, 2019Assignee: Allena Pharmaceuticals, Inc.Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
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Publication number: 20180250371Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: ApplicationFiled: October 23, 2017Publication date: September 6, 2018Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
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Publication number: 20180214522Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: ApplicationFiled: October 23, 2017Publication date: August 2, 2018Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
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Patent number: 9821041Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: GrantFiled: September 2, 2015Date of Patent: November 21, 2017Assignee: Allena Pharmaceuticals, Inc.Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
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Publication number: 20160144094Abstract: Compositions of peritoneal dialysis solutions and metabolizing enzymes, and their uses to treat disorders associated with elevated levels of metabolites are disclosed. Animal models of hyperoxalemia are also disclosed.Type: ApplicationFiled: June 6, 2014Publication date: May 26, 2016Inventors: Alexey MARGOLIN, Danica GRUJIC, Stefan PIERZYNOWSKI
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Publication number: 20160051647Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: ApplicationFiled: September 2, 2015Publication date: February 25, 2016Applicant: AJINOMOTO ALTHEA, INC.Inventors: BHAMI C. SHENOY, TERESA G. CACHERO, JOHN SHIN, LEKAI ZHANG, AFTAB RASHID, DANICA GRUJIC, REENA J. PATEL, MARGARET ELLEN MCGRATH
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Patent number: 9155785Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: GrantFiled: May 21, 2014Date of Patent: October 13, 2015Assignee: AJINOMOTO ALTHEA, INC.Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
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Publication number: 20150004204Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: ApplicationFiled: May 21, 2014Publication date: January 1, 2015Inventors: Bhami C. SHENOY, Teresa G. Cachero, John SHIN, Lekai ZHANG, Aftab RASHID, Danica GRUJIC, Reena J. Patel, Margaret Ellen MCGRATH
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Patent number: 8741284Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: GrantFiled: February 13, 2012Date of Patent: June 3, 2014Assignee: Althea Technologies, Inc.Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
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Publication number: 20120308545Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: ApplicationFiled: February 13, 2012Publication date: December 6, 2012Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
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Patent number: 8142775Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: GrantFiled: August 2, 2007Date of Patent: March 27, 2012Assignee: Althea Technologies, Inc.Inventors: Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
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Publication number: 20110171268Abstract: Compositions containing uricase are disclosed. Methods of treating a disorder associated with elevated uric acid concentrations using uricase are also described. Compositions containing uricase and catalase are also disclosed. Methods of treating a disorder associated with elevated uric acid concentrations using uricase and catalase are also described.Type: ApplicationFiled: March 24, 2009Publication date: July 14, 2011Applicant: Althea Technologies, Inc.Inventors: Bhami Shenoy, Danica Grujic, Reena Patel, Vinney George, Margaret Mcgrath, Nazer Khalaf, Emma Watson
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Publication number: 20080038246Abstract: Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.Type: ApplicationFiled: August 2, 2007Publication date: February 14, 2008Applicant: ALTUS PHARMACEUTICALS INC.Inventors: Bhami Shenoy, Teresa Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena Patel, Margaret McGrath
