Patents by Inventor Daniel B. Patience

Daniel B. Patience has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibiting agents for bruton's tyrosine kinase
    Patent number: 11858926
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Grant
    Filed: July 22, 2022
    Date of Patent: January 2, 2024
    Assignee: BIOGEN MA INC.
    Inventors: Brian T. Hopkins, Bin Ma, Robin Prince, Isaac Marx, Joseph P. Lyssikatos, Fengmei Zheng, Matthew Peterson, Daniel B. Patience
  • Crystalline polymorphs of Bruton's tyrosine kinase inhibitors
    Patent number: 11820760
    Abstract: Provided are crystalline forms of (R)-1-(tert-butyl)-N-(8-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-2-(oxetan-3-yl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-5-yl)-1H-1,2,3-triazole-4-carboxamide, pharmaceutical compositions, methods of use and methods of making thereof.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: November 21, 2023
    Assignee: BIOGEN MA INC.
    Inventors: Fengmei Zheng, Anton Peterson, Kalyan Vasudevan, Chaomin Li, Daniel B. Patience, Yiqing Lin
  • INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE
    Publication number: 20230147490
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Application
    Filed: July 22, 2022
    Publication date: May 11, 2023
    Inventors: Brian T. HOPKINS, Bin MA, Robin PRINCE, Isaac MARX, Joseph P. LYSSIKATOS, Fengmei ZHENG, Matthew PETERSON, Daniel B. PATIENCE
  • PROCESS FOR PREPARING ALPHA-CARBOXAMIDE PYRROLIDINE DERIVATIVES
    Publication number: 20220356154
    Abstract: The disclosure relates to novel processes for preparing ?-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and to novel intermediates for use in said process along with processes for preparing said intermediates.
    Type: Application
    Filed: November 24, 2021
    Publication date: November 10, 2022
    Inventors: Weirong Chen, Vinny Couming, Erwin Irdam, William F. Kiesman, Daw-long A. Kwok, Tamera L. Mack, Suzanne M. Opalka, Daniel B. Patience, Donald G. Walker, Wenli Liang
  • Inhibiting agents for Bruton's tyrosine kinase
    Patent number: 11427577
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Grant
    Filed: February 24, 2021
    Date of Patent: August 30, 2022
    Assignee: BIOGEN MA INC.
    Inventors: Brian T. Hopkins, Bin Ma, Robin Prince, Isaac Marx, Joseph P. Lyssikatos, Fengmei Zheng, Matthew Peterson, Daniel B. Patience
  • CRYSTALLINE POLYMORPHS OF BRUTON'S TYROSINE KINASE INHIBITORS
    Publication number: 20210387972
    Abstract: Provided are crystalline forms of (R)-1-(tert-butyl)-N-(8-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-2-(oxetan-3-yl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-5-yl)-1H-1,2,3-triazole-4-carboxamide, pharmaceutical compositions, methods of use and methods of making thereof.
    Type: Application
    Filed: October 15, 2019
    Publication date: December 16, 2021
    Applicant: Biogen MA Inc.
    Inventors: Fengmei ZHENG, Anton PETERSON, Kalyan VASUDEVAN, Chaomin LI, Daniel B. PATIENCE, Yiqing LIN
  • Process for preparing alpha-carboxamide pyrrolidine derivatives
    Patent number: 11192856
    Abstract: The invention relates to a novel process for preparing a-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and to novel intermediates for use in said process along with processes for preparing said intermediates.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: December 7, 2021
    Assignee: Biogen Inc.
    Inventors: Weirong Chen, Vinny Couming, Erwin Irdam, William F. Kiesman, Daw-Long A. Kwok, Tamera L. Mack, Suzanne M. Opalka, Daniel B. Patience, Donald G. Walker, Wenli Liang
  • INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE
    Publication number: 20210340135
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Application
    Filed: February 24, 2021
    Publication date: November 4, 2021
    Inventors: Brian T. Hopkins, Bin Ma, Robin Prince, Isaac Marx, Joseph P. Lyssikatos, Fengmei Zheng, Matthew Peterson, Daniel B. Patience
  • Inhibiting agents for Bruton's tyrosine kinase
    Patent number: 10961237
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: March 30, 2021
    Assignee: BIOGEN MA INC.
    Inventors: Brian T. Hopkins, Bin Ma, Robin Prince, Isaac Marx, Joseph P. Lyssikatos, Fengmei Zheng, Matthew Peterson, Daniel B. Patience
  • PROCESS FOR PREPARING ALPHA-CARBOXAMIDE PYRROLIDINE DERIVATIVES
    Publication number: 20200270206
    Abstract: The invention relates to a novel process for preparing a-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and to novel intermediates for use in said process along with processes for preparing said intermediates.
    Type: Application
    Filed: October 5, 2018
    Publication date: August 27, 2020
    Inventors: Weirong Chen, Vinny Couming, Erwin Irdam, William F. Kiesman, Daw-long A. Kwok, Tamera L. Mack, Suzanne M. Opalka, Daniel B. Patience, Donald G. Walker, Wenli Liang
  • INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE
    Publication number: 20200239459
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Application
    Filed: August 7, 2019
    Publication date: July 30, 2020
    Inventors: Brian T. Hopkins, Bin Ma, Robin Prince, Isaac Marx, Joseph P. Lyssikatos, Fengmei Zheng, Matthew Peterson, Daniel B. Patience
  • Inhibiting agents for Bruton's tyrosine kinase
    Patent number: 10189829
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: January 29, 2019
    Assignee: BIOGEN MA INC.
    Inventors: Brian T. Hopkins, Bin Ma, Robin Prince, Isaac Marx, Joseph P. Lyssikatos, Fengmei Zheng, Matthew Peterson, Daniel B. Patience
  • INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE
    Publication number: 20180362522
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Application
    Filed: August 27, 2018
    Publication date: December 20, 2018
    Inventors: Brian T. Hopkins, Bin Ma, Robin Prince, Isaac Marx, Joseph P. Lyssikatos, Fengmei Zheng, Matthew Peterson, Daniel B. Patience
  • INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE
    Publication number: 20180297992
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
    Type: Application
    Filed: April 13, 2018
    Publication date: October 18, 2018
    Inventors: Brian T. Hopkins, Bin Ma, Robin Prince, Isaac Marx, Joseph P. Lyssikatos, Fengmei Zheng, Matthew Peterson, Daniel B. Patience