Abstract: This invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human subject will respond or not to treatment with acetylsalicylic acid.

Abstract: This invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human subject will respond or not to treatment with acetylsalicylic acid.

Abstract: This invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human subject will respond or not to treatment with acetylsalicylic acid.

Abstract: This invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human subject will respond or not to treatment with acetylsalicylic acid.

Abstract: This invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human subject will respond or not to treatment with acetylsalicylic acid.

Abstract: An apparatus includes a slotted multi-nozzle grid with a plate having multiple elongated slotlettes through the plate. Each of at least some of the slotlettes has a convergent input, a divergent output, and a narrower throat portion separating the convergent input and the divergent output. At least some of the slotlettes are arranged in multiple rows. The plate further includes multiple cooling channels through the plate. At least some of the cooling channels are located between the rows of slotlettes. Each cooling channel is configured to transport coolant through the plate in order to cool the plate, such as to cool the plate as hot combustion gases pass through the plate. Each of at least some of the rows may include at least two slotlettes, and two adjacent slotlettes in one row may be separated by a structural ligament (which may have a tear-drop cross-sectional shape).

Abstract: A projectile includes a propulsion booster for producing pressurized gases, a nozzle for expelling the pressurized gases produced by the booster, and a supplementary integrated actuation system. The integrated actuation system selectively directs propellant from a storage reservoir of the integrated actuation system through an interiorly-located outlet of the integrated actuation system located at the nozzle and into the nozzle, thus changing a direction of the pressurized gases expelled by the booster. The integrated actuation system also selectively directs propellant from the storage reservoir through a peripherally-located outlet of the integrated actuation system, to produce thrust at an external periphery of the projectile, thus diverting the projectile.

Abstract: A projectile includes a propulsion booster for producing pressurized gases, a nozzle for expelling the pressurized gases produced by the booster, and a supplementary integrated actuation system. The integrated actuation system selectively directs propellant from a storage reservoir of the integrated actuation system through an interiorly-located outlet of the integrated actuation system located at the nozzle and into the nozzle, thus changing a direction of the pressurized gases expelled by the booster. The integrated actuation system also selectively directs propellant from the storage reservoir through a peripherally-located outlet of the integrated actuation system, to produce thrust at an external periphery of the projectile, thus diverting the projectile.

Abstract: An apparatus includes a slotted multi-nozzle grid with a plate having multiple elongated slotlettes through the plate. Each of at least some of the slotlettes has a convergent input, a divergent output, and a narrower throat portion separating the convergent input and the divergent output. At least some of the slotlettes are arranged in multiple rows. The plate further includes multiple cooling channels through the plate. At least some of the cooling channels are located between the rows of slotlettes. Each cooling channel is configured to transport coolant through the plate in order to cool the plate, such as to cool the plate as hot combustion gases pass through the plate. Each of at least some of the rows may include at least two slotlettes, and two adjacent slotlettes in one row may be separated by a structural ligament (which may have a tear-drop cross-sectional shape).

Abstract: The invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human subject will respond or not to treatment with acetylsalicylic acid.

Abstract: A rocket multi-nozzle grid assembly includes an insulator grid, a plurality of refractory nozzle fittings and a grid support plate. The grid support plate braces the plurality of refractory nozzle fittings and the insulator grid. The insulator grid includes insulator orifices, each of the nozzle fittings includes a fitting orifice and the grid support plate includes a plurality of plate orifices. The rocket multi-nozzle grid assembly includes a plurality nozzles. Each nozzle includes a plate orifice aligned with one insulator orifice and one fitting orifice. Exhaust gases are directed through the plurality of nozzles. The multi-nozzle grid assembly substantially maintains its surface area throughout operation of a rocket motor.

Abstract: This invention relates to methods for predicting risk of developing age-related macular degeneration (AMD), based on detecting the presence of certain genetic variants on chromosome 16 that are associated with increased incidence of AMD.

Abstract: A rocket multi-nozzle grid assembly includes an insulator grid, a plurality of refractory nozzle fittings and a grid support plate. The grid support plate braces the plurality of refractory nozzle fittings and the insulator grid. The insulator grid includes insulator orifices, each of the nozzle fittings includes a fitting orifice and the grid support plate includes a plurality of plate orifices. The rocket multi-nozzle grid assembly includes a plurality nozzles. Each nozzle includes a plate orifice aligned with one insulator orifice and one fitting orifice. Exhaust gases are directed through the plurality of nozzles. The multi-nozzle grid assembly substantially maintains its surface area throughout operation of a rocket motor. In one example, the surface area is maintained through ablation of the insulator grid. In another example, the surface area is maintained through cooling of the plurality of nozzle fittings with the ablated fragments passing through the nozzles.

Abstract: A propulsion system, such as for use in a missile, includes a multinozzle grid having a pair of plates that are separably mechanically coupled together. When coupled together in a first configuration, the plates provide multiple nozzles in a first nozzle configuration (geometry). Separation of the plates, such as by separating an aft plate from a forward plate that remains with the missile, reconfigures the multinozzle grid to a second configuration that has nozzles in a second nozzle configuration (geometry). The nozzle configurations may be suitable for different types of propulsion mechanisms. The hybrid propulsion system utilizing the multinozzle grid may include a pair of pressurized gas sources, for example a solid rocket fuel and a combustion chamber for a ramjet.

Abstract: This invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human subject will respond or not to treatment with acetylsalicylic acid.

Abstract: This invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human subject will respond or not to treatment with acetylsalicylic acid.

Abstract: A propulsion system includes a canted multinozzle plate, which has a multitude of small nozzles angled (not perpendicular) to major surfaces of the multinozzle grid plate. The multinozzle plate may be a cylindrical section or plate, and the multitude of nozzles may be substantially axisymmetric about the cylindrical plate. The propulsion system includes a pressurized gas source which may be placed either forward or aft of the multinozzle grid plate. The propulsion system may have a conical insert, an internal flow separator cone, to aid in changing directions of flow from the pressurized gas source, to divert the flow through the multiple nozzles.

Abstract: A propulsion system includes a canted multinozzle plate, which has a multitude of small nozzles angled (not perpendicular) to major surfaces of the multinozzle grid plate. The multinozzle plate may be a cylindrical section or plate, and the multitude of nozzles may be substantially axisymmetric about the cylindrical plate. The propulsion system includes a pressurized gas source which may be placed either forward or aft of the multinozzle grid plate. The propulsion system may have a conical insert, an internal flow separator cone, to aid in changing directions of flow from the pressurized gas source, to divert the flow through the multiple nozzles.

Abstract: A propulsion system, such as for use in a missile, includes a multinozzle grid having a pair of plates that are separably mechanically coupled together. When coupled together in a first configuration, the plates provide multiple nozzles in a first nozzle configuration (geometry). Separation of the plates, such as by separating an aft plate from a forward plate that remains with the missile, reconfigures the multinozzle grid to a second configuration that has nozzles in a second nozzle configuration (geometry). The nozzle configurations may be suitable for different types of propulsion mechanisms. The hybrid propulsion system utilizing the multinozzle grid may include a pair of pressurized gas sources, for example a solid rocket fuel and a combustion chamber for a ramjet.

Abstract: This invention relates to nucleotide polymorphisms in the human Apo(a) gene and to the use of Apo(a) nucleotide polymorphisms in identifying whether a human subject will respond or not to treatment with acetylsalicylic acid.