Patents by Inventor Daniel Dransfield

Daniel Dransfield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS
    Publication number: 20070243139
    Abstract: The invention provides compositions and methods for therapeutic and diagnostic applications.
    Type: Application
    Filed: January 19, 2007
    Publication date: October 18, 2007
    Applicants: BRACCO INTERNATIONAL B.V., DYAX CORPORATION
    Inventors: Christophe Arbogast, Philippe Bussat, Hong Fan, Karen Linder, Edmund Marinelli, Palaniappa Nanjappan, Adrian Nunn, Radhakrishna Pillai, Sibylle Pochon, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf Swenson, Mathew Von Wronski, Aaron Sato, Sharon Walker, Daniel Dransfield
  • Metalloproteinase binding proteins
    Publication number: 20070217997
    Abstract: Proteins that bind to matrix metalloproteinase 14 and methods of using such proteins are described.
    Type: Application
    Filed: December 29, 2006
    Publication date: September 20, 2007
    Inventors: Laetitia Devy, Henk Pieters, Robert Ladner, Rene Hoet, Daniel Dransfield, Clive Wood
  • MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS
    Publication number: 20070172428
    Abstract: The invention provides compositions and methods for therapeutic and diagnostic applications.
    Type: Application
    Filed: March 21, 2007
    Publication date: July 26, 2007
    Applicants: BRACCO INTERNATIONAL B.V., DYAX CORPORATION
    Inventors: Christophe Arbogast, Philippe Bussat, Hong Fan, Karen Linder, Edmund Marinelli, Palaniappa Nanjappan, Adrian Nunn, Radhakrishna Pillai, Sibylle Pochon, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf Swenson, Mathew Von Wronski, Aaron Sato, Sharon Walker, Daniel Dransfield
  • Tie complex binding proteins
    Publication number: 20060057138
    Abstract: Tie1 and Tie2 are receptor tyrosine kinase proteins that include a transmembrane domain. Tie1 and Tie2 are present on endothelial cells. This disclosure describes agents, such as antibodies, that bind to Tie1, Tie2, and Ang, including ones that inhibit endothelial cell activity and angiogenesis. The agents can be used to treat angiogenesis-associated disorders.
    Type: Application
    Filed: August 9, 2005
    Publication date: March 16, 2006
    Inventors: Clive Wood, Daniel Dransfield, Henk Pieters, Rene Hoet, Simon Hufton
  • Metalloproteinase-binding proteins
    Publication number: 20060036076
    Abstract: Disclosed are antibodies that interact with a matrix metalloproteases such as MMP-26. Exemplary antibodies inhibit MMP-26 activity. These antibodies can be used, e.g., to treat or prevent metastatic disorders, hyperproliferative disorders, disorders which are characterized by excessive extracellular matrix degradation, and inflammatory disorders.
    Type: Application
    Filed: November 19, 2004
    Publication date: February 16, 2006
    Inventors: Daniel Dransfield, Kristin Rookey, Robert Ladner
  • Tie complex binding proteins
    Publication number: 20060024297
    Abstract: Tie1 and Tie2 are receptor tyrosine kinase proteins that include a transmembrane domain. Tie1 and Tie2 are present on endothelial cells. This disclosure describes agents, such as antibodies, that bind to Tie1, Tie2, and Ang, including ones that inhibit endothelial cell activity.
    Type: Application
    Filed: February 2, 2005
    Publication date: February 2, 2006
    Inventors: Clive Wood, Daniel Dransfield, Henk Pieters, Rene Hoet, Simon Hufton
  • KDR and VEGF/KDR binding peptides
    Publication number: 20050250700
    Abstract: The present invention provides, inter alia, peptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 ?M), and dimer and multimeric constructs comprising these polypeptides.
    Type: Application
    Filed: September 13, 2004
    Publication date: November 10, 2005
    Inventors: Aaron Sato, Daniel Sexton, Daniel Dransfield, Robert Ladner, Christophe Arbogast, Phillipe Bussat, Hong Fan, Sudha Khurana, Karen Linder, Edmund Marinelli, Palaniappa Nanjappan, Adrian Nunn, Radhakrishna Pillai, Sibylle Pochon, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf Swenson, Mathew Von Wronski
  • Peptides that specifically bind HGF receptor (cMet) and uses thereof
    Publication number: 20050214859
    Abstract: A polypeptide or multimeric polypeptide construct having the ability to bind to cMet or a complex comprising cMet and HGF, and methods for use are disclosed.
    Type: Application
    Filed: March 3, 2004
    Publication date: September 29, 2005
    Inventors: Daniel Dransfield, Aaron Sato, Robert Ladner, Regi Thomas, Palaniappa Nanjappan
  • KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
    Publication number: 20050100963
    Abstract: The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 ?M), and dimer and multimeric constructs comprising these polypeptides.
    Type: Application
    Filed: September 11, 2003
    Publication date: May 12, 2005
    Applicants: Dyax Corporation
    Inventors: Aaron Sato, Daniel Sexton, Daniel Dransfield, Robert Ladner, Christophe Arbogast, Philippe Bussat, Hong Fan, Sudha Khurana, Karen Linder, Edmund Marinelli, Palaniappa Nanjappan, Adrian Nunn, Radhakrishna Pillai, Sibylle Pochon, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf Swenson, Mathew Von Wronski
  • Multivalent constructs for therapeutic and diagnostic applications
    Publication number: 20050027105
    Abstract: The invention provides compositions and methods for therapeutic and diagnostic applications.
    Type: Application
    Filed: September 11, 2003
    Publication date: February 3, 2005
    Inventors: Christophe Arbogast, Philippe Bussat, Hong Fan, Karen Linder, Edmund Marinelli, Palaniappa Nanjappan, Adrian Nunn, Radhakrishna Pillai, Sibylle Pochon, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf Swenson, Mathew Von Wronski, Aaron Sato, Sharon Walker, Daniel Dransfield