Abstract: Provided herein are dosing and combination therapies with a CD39 antibody, a PD-1 antibody, and FOLFOX or CAPDX in gastric cancer.

Abstract: A method and system for determining a route map and a route for a vehicle. Generating the route map comprises obtaining historical data comprising a plurality of data points for each of a plurality of vehicles from storage and determining a plurality of nodes each representing a subset of the data points. The historical data is applied to the plurality of nodes to determine the closest node for each vehicle. The nodes are ordered for each of the plurality of vehicles in the historical data by time; and a directed edge is generated between a first and second node of the plurality of ordered nodes, based on when the historical data indicates that a given vehicle has transited from the first node and the second node. A route is determined for the vehicle based on the generated route map and outputted route to a control system.

Abstract: The invention relates to a method for producing a cooling device (10), which has at least one hollow body (30) made of a first material having good thermal conduction and a base body made of a second material having good thermal conduction, and a pre-product for the production of a cooling device (10) and a cooling device (10) for an electrical assembly and an electrical assembly having a cooling device of this kind.

Abstract: An electric traction machine, a motor vehicle, and a method for controlling dissipated heat in the electrical power plant of the motor vehicle are described herein. The power plant is supplied with a current, where, in order to provide a predetermined amount of dissipated heat, a ratio between a field-forming and a torque-forming current deviating from an optimum ratio for a respective operating point of the power plant is prescribed. The predetermined dissipated heat is provided by a power plant embodied as a magnet-less three-phase alternator while a rotor current flowing through a rotor of the three-phase alternator is adjusted, the field-forming and the torque-forming currents being prescribed such that acoustic interference signals of the three-phase alternator are minimized by the ratio, and the rotor current is adjusted such that the predetermined dissipated heat is provided by a combination of the rotor current and the ratio minimizing the interference signals.

Abstract: An electric traction machine, a motor vehicle, and a method for controlling dissipated heat in the electrical power plant of the motor vehicle are described herein. The power plant is supplied with a current, where, in order to provide a predetermined amount of dissipated heat, a ratio between a field-forming and a torque-forming current deviating from an optimum ratio for a respective operating point of the power plant is prescribed. The predetermined dissipated heat is provided by a power plant embodied as a magnet-less three-phase alternator while a rotor current flowing through a rotor of the three-phase alternator is adjusted, the field-forming and the torque-forming currents being prescribed such that acoustic interference signals of the three-phase alternator are minimized by the ratio, and the rotor current is adjusted such that the predetermined dissipated heat is provided by a combination of the rotor current and the ratio minimizing the interference signals.

Abstract: The invention relates to a method for producing a cooling device (10), which has at least one hollow body (30) made of a first material having good thermal conduction and a base body made of a second material having good thermal conduction, and a pre-product for the production of a cooling device (10) and a cooling device (10) for an electrical assembly and an electrical assembly having a cooling device of this kind.