Patents by Inventor Daniel F. HOFT

Daniel F. HOFT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENZYMATICALLY INACTIVE GRANZYME A AND USES THEREFORE
    Publication number: 20240100133
    Abstract: The present disclosure is directed to recombinant mutant Granzyme A molecules that lack enzymatic activity and their use in inhibiting Mycobacterium tuberculosis and treating the related disease states.
    Type: Application
    Filed: August 1, 2023
    Publication date: March 28, 2024
    Applicant: Saint Louis University
    Inventors: Daniel F. HOFT, Valerio RASI
  • PEPTIDES FOR INDUCING HETEROSUBTYPIC INFLUENZA T CELL RESPONSES
    Publication number: 20210380644
    Abstract: The present invention provides compositions and methods for generation of an anti-influenza immune response. In particular, conserved T cell epitopes within matrix protein and nucleoprotein components of influenza virus have been identified and further screened for those structures that will bind either or both of HLA I and II molecules. Methods for vaccinating subjects with formulations of such peptides for the treatment or prevention of influenza infection also are described.
    Type: Application
    Filed: October 25, 2019
    Publication date: December 9, 2021
    Applicants: Saint Louis University, EpiVax, Inc.
    Inventors: Daniel F. HOFT, Christopher S. EICKHOFF, Annie DE GROOT