Patents by Inventor Daniel Frimannsson

Daniel Frimannsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MRNA treatment nanoparticles
    Patent number: 11879126
    Abstract: Provided herein are examples of mRNA treatment nanoparticles and methods of using them to treat a patient. An mRNA treatment nanoparticle may include one or more mRNAs encoding a tumor-specific antigen and an immunomodulatory agent; and a delivery vehicle molecule encapsulating the one or more mRNAs.
    Type: Grant
    Filed: October 20, 2022
    Date of Patent: January 23, 2024
    Assignee: Nutcracker Therapeutics, Inc.
    Inventors: Samuel Deutsch, Daniel Frimannsson, Nicole Fay, Colin McKinlay, Ole Haabeth
  • MRNA TREATMENT NANOPARTICLES
    Publication number: 20230193288
    Abstract: Provided herein are examples of mRNA treatment nanoparticles and methods of using them to treat a patient. An mRNA treatment nanoparticle may include one or more mRNAs encoding a tumor-specific antigen and an immunomodulatory agent; and a delivery vehicle molecule encapsulating the one or more mRNAs.
    Type: Application
    Filed: October 20, 2022
    Publication date: June 22, 2023
    Inventors: Samuel DEUTSCH, Daniel FRIMANNSSON, Nicole FAY, Colin McKINLAY
  • CHIMERIC RECEPTOR SENSORS
    Publication number: 20220396609
    Abstract: Provided herein are generalized extracellular molecule sensors (GEMSs) and polynucleotides encoding the GEMSs. Also provided herein are methods of making and using the GEMSs, such as therapeutic and diagnostic methods.
    Type: Application
    Filed: October 30, 2020
    Publication date: December 15, 2022
    Inventors: Russell Morrison Gordley, Daniel Frimannsson, Michelle Elizabeth Hung
  • COMBINATORIAL CANCER IMMUNOTHERAPY
    Publication number: 20220378842
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Application
    Filed: June 23, 2022
    Publication date: December 1, 2022
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
  • Combinatorial cancer immunotherapy
    Patent number: 11419898
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: August 23, 2022
    Assignee: SENTI BIOSCIENCES, INC.
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
  • Fusion Constructs for Controlling Protein Function
    Publication number: 20220090040
    Abstract: Described herein are engineered fusion proteins comprising a variant protease (e.g., an HCV NS3 protease) fused to a polypeptide of interest and a cognate protease cleavage site. The cleavability of the cognate protease cleavage site enables the controllability of one or more functions of the polypeptide of interest. Additionally disclosed are methods for generating engineered fusion proteins as well as their therapeutic use.
    Type: Application
    Filed: January 24, 2020
    Publication date: March 24, 2022
    Applicants: Senti Biosciences, Inc., Senti Biosciences, Inc.
    Inventors: Daniel Frimannsson, Philip Janmin Lee, Timothy Kuan-Ta Lu, Russell Morrison Gordley
  • COMBINATORIAL CANCER IMMUNOTHERAPY
    Publication number: 20210228640
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Application
    Filed: March 31, 2021
    Publication date: July 29, 2021
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
  • Combinatorial cancer immunotherapy
    Patent number: 10993967
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: May 4, 2021
    Assignee: SENTI BIOSCIENCES, INC.
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
  • COMBINATORIAL CANCER IMMUNOTHERAPY
    Publication number: 20200171093
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Application
    Filed: October 17, 2019
    Publication date: June 4, 2020
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson