Abstract: The invention relates generally to polypeptides that include a cleavable moiety that is a substrate for at least one matrix metalloprotease (MMP), to activatable antibodies and other larger molecules that include the cleavable moiety that is a substrate for at least one MMP protease, and to methods of making and using these polypeptides that include a cleavable moiety that is a substrate for at least one MMP protease in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: Materials and methods for producing tactile anatomical structures are described. These are intended primarily for use for high-value, in-depth surgical training for novice or expert surgeons. They may also be used for medical education, sales demonstrations, or for research and development. Examples of embodiments refer to their use in knee and shoulder models. The tactile tissue-simulating structures include, amongst others: skin, fat, muscles, ligaments, tendons, cartilage, bursa, fat pad, and periosteum. A method for creating a musculotendinous junction is also described.

Abstract: Systems, methods, and instructions of computer-readable media may include obtaining, at a client machine, a user-selected configuration parameter for an orbit simulation; sending, from the client machine to a remote system, via a network connection, a first set of configuration parameters for the orbit simulation, wherein the first set of configuration parameters comprise the user-selected configuration parameter; receiving, at the client device from the remove device, via the network connection, a stream of orbital data comprising points along an orbit, wherein the points along the orbit are determined by the remote system based on the first set of configuration parameters; and presenting, at a display, a dynamic rendering of the orbit simulation, wherein the orbit simulation is based on the stream of orbital data.

Abstract: The invention relates generally to polypeptides that include a cleavable moiety that is a substrate for at least one matrix metalloprotease (MMP), to activatable antibodies and other larger molecules that include the cleavable moiety that is a substrate for at least one MMP protease, and to methods of making and using these polypeptides that include a cleavable moiety that is a substrate for at least one MMP protease in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, humanized antibodies and antibody fragments, that specifically bind a MS4A4A polypeptide, e.g., a mammalian MS4A4A or human MS4A4A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.

Abstract: A long-distance learning system includes an instruction studio and one or more remotely located classrooms for students. Each of the student's participation, academic performance, and use of digital resources for a class is evaluated in real time and assigned a color, so the instructor can easily assess each student's progress in the class when presented to the instructor in a display which is only for the instructor.

Abstract: The present invention comprises a system and methods for the conversion of time-recorded seismic data, or images made from them after conversion of time to depth, into data structures that can be imported into and used in a three-dimensional geographic information system. The system and methods are robust with respect to the forms in which the seismic data is input into the invention. The system is general in that it is applicable to cross-sectional data other than those derived in seismic surveys and requires very non-restrictive definitions of cross-sectional planes, their orientations and datums with respect to the volumes they intersect.

Abstract: A long-distance learning system includes an instruction studio and one or more remotely located classrooms for students. Each of the student's participation, academic performance, and use of digital resources for a class is evaluated in real time and assigned a color, so the instructor can easily assess each student's progress in the class when presented to the instructor in a display which is only for the instructor.

Abstract: An internet information network is provided by linking content from a plurality of in-webpage views on a plurality of webpages using one or more page view (PV) navigator(s). Each PV navigator comprises a PV-anchor marking an in-webpage view on a webpage and one or more PV-links accessible (directly or indirectly) from said webpage. Each PV-link when activated navigates a user to a distinct PV-anchor on a distinct webpage. The application of a plurality of PV navigators (PV navigation system) to link the content (of in-webpage views) arranged according to a user-defined standard allows the user to browse for similar information efficiently across the information network while maintaining a focused orientation with respect to content of interest. The integration of a PV-database of PV-link records into a PV-navigator and PV-search means allows for the construction of scalable, custom and dynamic in-webpage view information networks according to the present disclosure.

Abstract: An instrument panel system includes box sections that increase the stiffness, rigidity, and natural frequency of the instrument panel system. A two-piece instrument panel system provides a two-tone appearance with differing die draws and grains.

Abstract: An instrument panel system includes box sections that increase the stiffness, rigidity, and natural frequency of the instrument panel system. A two-piece instrument panel system provides a two-tone appearance with differing die draws and grains.

Abstract: A portable knockdown table assembly has a separable collapsible slatted tabletop supported on a collapsible base in a setup condition. A pair of bag retaining straps carried by a tabletop slat releasably retain a disposable trash bag in a depending and open condition at one end of the table when the table assembly is setup and may also be employed to releasably secure the slatted tabletop in its collapsed or bundled condition when the table assembly is in its knockdown condition.

Abstract: A portable sling chair having a frame formed by a plurality of rigid axially elongated collapsible tubular frame members including a main frame member and a rear frame member connected for pivotal and axial sliding movement relative to each other, a collapsible front support member, a collapsible frame front support assembly, a collapsible frame rear support assembly, and at least one connecting member connecting the main frame member and the rear frame member to maintain the frame in a substantially static condition when the frame is resting on a supporting surface in setup condition. A rectangular panel made from flexible material is supported at its opposite ends by collapsible front and rear panel support members, extends therebetween, and defines contiguous chair seat and back portions when the frame is in its setup condition. All of the frame members are disposed in generally side-by-side relation to each other in the collapsed condition of the frame and form a compact bundle.

Abstract: A folding chair for use on both level and inclined supporting surfaces has a back support and a front leg assembly pivotally connected to a bottom for independent forward and rearward movement relative to the bottom and to each other between operative and collapsed positions. A flexible retaining strap of adjustable length maintains the front legs in selected angular position relative to the bottom and holds the bottom in a generally horizontally disposed position when the chair is supported on an inclined surface. A flexible carrying strap of adjustable length maintains the back in a comfortable back supporting position relative to the bottom. Lifting the chair by the carrying strap automatically collapses the chair into a compact bundle which may be carried on a shoulder by the carrying strap. Collapsible rear legs may be provided for supporting the chair bottom at a conventional chair seat height above a supporting surface.