Patents by Inventor Daniel Guerrier

Daniel Guerrier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ITIH5 AS A DIAGNOSTIC MARKER OF UTERINE DEVELOPMENT AND FUNCTIONAL DEFECTS
    Publication number: 20150038778
    Abstract: The invention relates to the use of ITIH5 as a biomarker of endometrium receptivity to embryo implantation. Also provided are methods and kits for using this biomarker for detecting the receptivity state of the endometrium of a mammal to embryo implantation, for diagnosing infertility in a female mammal, for the early diagnosis of pregnancy, for detecting the window of embryo implantation in the endometrium of a female mammal, for in vitrofertilization of a female mammal, and for diagnosing endometriosis.
    Type: Application
    Filed: March 14, 2013
    Publication date: February 5, 2015
    Inventors: Daniel Guerrier, Karine Morel
  • Butenoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and use for the treatment of dyslipidaemia, atherosclerosis and diabetes
    Patent number: 8247448
    Abstract: The present invention relates to butenoic acid derivatives of the formula I: in which R, R1, R2 and R3 are as defined in the description, and also to processes for the preparation thereof, to pharmaceutical compositions comprising them and to their use for the treatment of dyslipidaemia, atherosclerosis and diabetes.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: August 21, 2012
    Assignee: Merck Patent GmbH
    Inventors: Jean-Jacques Zeiller, Hervé Dumas, Valérie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gérard Ferrand, Yves Bonhomme
  • Hexenoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof
    Patent number: 8063067
    Abstract: Compounds of the formula (I): in which R, R1, R2 and R3 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions comprising them, and processes for the preparation of these compounds.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: November 22, 2011
    Assignee: Merck Patent GmbH
    Inventors: Jean Jacques Zeiller, Hervè Dumas, Valérie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gérard Ferrand, Yves Bonhomme
  • Butenoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them and use for the treatment of dyslipidaemia, atherosclerosis and diabetes
    Patent number: 7820847
    Abstract: The present invention relates to butenoic acid derivatives of the formula I: in which R, R1, R2 and R3 are as defined in the description, and also to processes for the preparation thereof, to pharmaceutical compositions comprising them and to their use for the treatment of dyslipidaemia, atherosclerosis and diabetes.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: October 26, 2010
    Assignee: Merck Patent GmbH
    Inventors: Jean-Jacques Zeiller, Hervé Dumas, Valérie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gérard Ferrand, Yves Bonhomme
  • Butenoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and use for the treatment of dyslipidaemia, atherosclerosis and diabetes
    Publication number: 20100261789
    Abstract: The present invention relates to butenoic acid derivatives of the formula I: in which R, R1, R2 and R3 are as defined in the description, and also to processes for the preparation thereof, to pharmaceutical compositions comprising them and to their use for the treatment of dyslipidaemia, atherosclerosis and diabetes.
    Type: Application
    Filed: June 23, 2010
    Publication date: October 14, 2010
    Inventors: Jean-Jacques Zeiller, Hervé Dumas, Valérie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gérard Ferrand, Yves Bonhomme
  • USE OF PENTADIENOIC ACID DERIVATIVES FOR THE TREATMENT OF HYPERURICEMIA
    Publication number: 20100160410
    Abstract: The use of a pentadienoic acid derivative of formula (I) for the preparation of a medicament for the prevention or treatment of hyperuricemia and/or one or several associated disorders or diseases, and/or for reducing the serum uric acid level of a subject. Medical compositions for these prevention and/or treatment, comprising such a pentadienoic acid derivative.
    Type: Application
    Filed: January 13, 2010
    Publication date: June 24, 2010
    Inventors: Robert Boizel, Pascale Fouqueray, Daniel Guerrier, Jean-Jacques Zeiller, Bertrand Brutzkus
  • Butanoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof
    Patent number: 7678831
    Abstract: Compounds of the formula (I): in which R, R1 and R2 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions comprising them, and . processes for the preparation of these compounds. Compounds of formula (I) are activators of PPAR? and PPAR? isoforms.
    Type: Grant
    Filed: April 6, 2005
    Date of Patent: March 16, 2010
    Assignee: Merck Patent GmbH
    Inventors: Jean Jacques Zeiller, Hervè Dumas, Valérie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gérard Ferrand, Yves Bonhomme
  • Hexenoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof
    Patent number: 7632846
    Abstract: Compounds of the formula (I): in which R, R1, R2 and R3 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions comprising them, and processes for the preparation of these compounds.
    Type: Grant
    Filed: April 6, 2005
    Date of Patent: December 15, 2009
    Assignee: Merck Patent Gesellschaft mit beschrankter
    Inventors: Jean Jacques Zeiller, Hervè Dumas, Valérie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gèrard Ferrand, Yves Bonhomme
  • HEXENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THEREOF
    Publication number: 20090286776
    Abstract: Compounds of the formula (I): in which R, R1, R2 and R3 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions comprising them, and processes for the preparation of these compounds.
    Type: Application
    Filed: July 23, 2009
    Publication date: November 19, 2009
    Inventors: Jean Jacques ZEILLER, Hervè Dumas, Valérie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gérard Ferrand, Yves Bonhomme
  • Butyric acid derivatives
    Patent number: 7491747
    Abstract: The present invention relates to a compound of the formula I: (Formula I) in which: A, B, R1, Z, n and R2 are as defined in claim 1. These compounds are useful in the treatment of dyslipidaemia, atherosclerosis and diabetes.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: February 17, 2009
    Assignee: Merck Patent GmbH
    Inventors: Roche Didier, Jean-Jacques Zeiller, Francis Contard, Valérie Guyard-Dangremont, Daniel Guerrier, Hervé Dupont, Jean-Jacques Berthelon
  • Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia
    Patent number: 7482484
    Abstract: Disclosed are Compounds of formula I And methods of use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: January 27, 2009
    Assignee: Merck Patent GmbH
    Inventors: Nathalie Adje, Michel Brunet, Didier Roche, Jean-Jacques Zeiller, Stéphane Yvon, Valérie Guyard-Dangremont, Francis Contard, Daniel Guerrier, Gérard Ferrand, Yves Bonhomme
  • Pentenoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof
    Patent number: 7465752
    Abstract: Compounds of the formula (I): in which R, R1, R2 and R3 are as defined in the description, to their use for the treatment of dyslipidaemia, atherosclerosis and diabetes, to pharmaceutical compositions comprising them and to the processes for the preparation of these compounds.
    Type: Grant
    Filed: April 6, 2005
    Date of Patent: December 16, 2008
    Assignee: Merck Patent GmbH
    Inventors: Jean Jacques Zeiller, Hervè Dumas, Valérie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gérard Ferrand, Yves Bonhomme
  • Hexenoic Acid Derivatives, Processes for the Preparation Thereof, Pharmaceutical Compositions Comprising Them, and Therapeutic Applications Thereof
    Publication number: 20080194564
    Abstract: Compounds of the formula (I): in which R, R1, R2 and R3 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions comprising them, and processes for the preparation of these compounds.
    Type: Application
    Filed: April 6, 2005
    Publication date: August 14, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Jean Jacques Zeiller, Herve Dumas, Valerie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gerard Ferrand, Yves Bonhomme
  • Butanoic Acid Derivatives, Processes For The Preparation Thereof, Pharmaceutical Compositions Comprising Them, And Therapeutic Applications Thereof
    Publication number: 20080032982
    Abstract: Compounds of the formula (I): in which R, R1 and R2 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions comprising them, and . processes for the preparation of these compounds. Compounds of formula (I) are activators of PPAR? and PPAR? isoforms.
    Type: Application
    Filed: April 6, 2005
    Publication date: February 7, 2008
    Inventors: Jean Zeiller, Herve Dumas, Valerie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gerard Ferrand, Yves Bonhomme
  • Dihydrobenzodiazepins and their use for treating dyslipidemia
    Patent number: 7323458
    Abstract: The invention concerns a benzodiazepin derivative of formula (I) and their use for treating dyslipidemia, atherosclerosis, diabetes and its complications.
    Type: Grant
    Filed: July 4, 2000
    Date of Patent: January 29, 2008
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Jean-Jacques Berthelon, Daniel Guerrier, Michel Brunet, Jean-Jacques Zeiller, Francis Contard, Fréderic Ausseil
  • Pentenoic Acid Derivatives, Processes For The Preparation Thereof, Pharmaceutical Compositions Comprising Them, And Therapeutic Applications Thereof
    Publication number: 20080015253
    Abstract: Compounds of the formula (I): in which R, R1, R2 and R3 are as defined in the description, to their use for the treatment of dyslipidaemia, atherosclerosis and diabetes, to pharmaceutical compositions comprising them and to the processes for the preparation of these compounds.
    Type: Application
    Filed: April 6, 2005
    Publication date: January 17, 2008
    Inventors: Jean Zeiller, Herve Dumas, Valerie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gerard Ferrand, Yves Bonhomme
  • Use of pentadienoic acid derivatives for the treatment of hyperuricemia
    Publication number: 20070099854
    Abstract: The use of a pentadienoic acid derivative of formula (I) for the preparation of a medicament for the prevention or treatment of hyperuricemia and/or one or several associated disorders or diseases, and/or for reducing the serum uric acid level of a subject. Medical compositions for these prevention and/or treatment, comprising such a pentadienoic acid derivative.
    Type: Application
    Filed: November 2, 2004
    Publication date: May 3, 2007
    Inventors: Robert Boizel, Pascale Fouqueray, Daniel Guerrier, Jean-Jacques Zeiller, Bertrand Brutzkus
  • Butenoic acid derivatives processes for the preparation thereof pharmaceutical compositions comprising them and use for the treatment of dyslipidaemia atherosclerosis and diabetes
    Publication number: 20060178434
    Abstract: The present invention relates to butenoic acid derivatives of the formula I: in which R, R1, R2 and R3 are as defined in the description, and also to processes for the preparation thereof, to pharmaceutical compositions comprising them and to their use for the treatment of dyslipidaemia, atherosclerosis and diabetes.
    Type: Application
    Filed: July 14, 2004
    Publication date: August 10, 2006
    Inventors: Jean-Jacques Zeiller, Herve Dumas, Valerie Guyard-Dangremont, Isabelle Berard, Francis Contard, Daniel Guerrier, Gerard Ferrand, Yves Bonhomme
  • Novel carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia
    Publication number: 20060111445
    Abstract: The present invention relates to a compound of the formula ((I): in which: n is an integer chosen from 1, 2 and 3; Y represents O; N—OR9, in which R9 represents H or a saturated hydrocarbon-based aliphatic group; CR10R11, in which R10 and R11, which may be identical or different, represent H or a saturated hydrocarbon-based aliphatic group; R1 and R2, which may be identical or different, represent H or a saturated aliphatic hydrocarbon-based chain; or alternatively R1 and R2 together form an optionally substituted saturated aliphatic hydrocarbon-based chain; the radicals R3 and R4, which may be identical or different, take any of the is meanings given above for R1 and R2, or alternatively R1 and the group R4 borne by the carbon alpha to CR1R2 represent nothing and a double bond links the CR1R2 carbon to the alpha CR3R4 carbon; or alternatively one of the radicals R1 and R2 forms with one of the radicals R3 and R4 an optionally substituted saturated or unsaturated aliphatic hydrocarbon-based chain; one of the
    Type: Application
    Filed: December 16, 2003
    Publication date: May 25, 2006
    Inventors: Nathalie Adje, Michel Brunet, Didier Roche, Jean-Jacques Zeiller, Stephane Yvon, Valerie Guyard-Dangremont, Francis Contard, Daniel Guerrier, Gerard Ferrand
  • Nitrosodiphenylamine derivatives and their pharmaceutical use against oxidative stress pathologies
    Publication number: 20050154232
    Abstract: Compounds of formula (I) in which each of the phenyl rings represented is optionally substituted one or more times; n represents an integer selected from 0, 1, Z, 3, 4 and 5; W represents —CO— or —SO—2; Z represents H; alkyl; aryl; or arylalkyl R1 represents any monovalent organic group; and the pharmaceutically acceptable salts thereof, can be used in the treatment of pathologies that are characterized by an oxidative stress condition.
    Type: Application
    Filed: February 12, 2003
    Publication date: July 14, 2005
    Inventors: Claude Lardy, Didier Festal, Lidia Caputo, Daniel Guerrier