Abstract: A passive heat exchanger includes an evaporator section including a heat exchange surface formed complementary to a surface of a gas turbine engine component to be cooled. The heat exchange surface is configured to be thermally coupled in conductive contact to the component surface. The heat exchanger further includes a condenser section coupled in passive convective flow communication with the evaporator section, and a working fluid contained within the evaporator section and the condenser section and configured to passively convect heat from the evaporator section to the condenser section.

Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.

Abstract: Techniques are included for providing a parallel pseudo infinite timeline monotonic clock that may be used to determine time and durations. A system clock is used to obtain an original time instant that anchors the pseudo infinite timeline to be parallel to a timeline of the system clock. The monotonic clock obtains time ticks from a monotonic tick supplier. The monotonic time ticks are used to determine times and durations, rather than relying on time instants obtained from the system clock. The use of a sliding window anchored at various times allows the parallel timeline to be almost infinite in implementation, rather than wrapping once a maximum value is reached. In addition, the accuracy of computations of time and duration are impervious to changes to the system clock, due to the use of the monotonic time ticks instead of obtaining multiple time instants from the system clock.

Abstract: An aerosol-generating article is provided for producing an inhalable aerosol when heated, the aerosol-generating article including: a hollow cylindrical rod of aerosol-generating substrate; a wrapper circumscribing the hollow cylindrical rod; and a hollow tube extending along a longitudinal axis of the hollow cylindrical rod and defining a central airflow channel of the aerosol-generating article, the hollow tube including a plurality of openings extending through a wall of the hollow tube, such that the aerosol-generating substrate in the hollow cylindrical rod is in fluid communication with the central airflow channel through the plurality of openings, and such that a ratio between a cumulative cross-sectional area of the plurality of openings and a cross-sectional area of the central airflow channel is from about 0.042 to about 0.672.

Abstract: An aerosol-generating device is provided, including a first atomiser assembly including a first mesh element defining a plurality of first nozzles each having a minimum diameter of equal to or less than 2.5 micrometres; a second atomiser assembly including a second mesh element defining a plurality of second nozzles each having a minimum diameter of between 3 micrometres and 10 micrometres; a first device connector configured to receive a first liquid reservoir and to supply a first liquid from the first liquid reservoir to the first atomiser assembly; and a second device connector configured to receive a second liquid reservoir and to supply a second liquid from the second liquid reservoir to the second atomiser assembly.

Abstract: An atomiser assembly is provided, including: an oscillation chamber having a cavity containing a liquid to be atomized, a liquid inlet configured to provide a supply of the liquid to be atomized to the cavity, an elastically deformable element, and a mesh element comprising a plurality of nozzles; and an actuator configured to oscillate the elastically deformable element, the oscillation chamber and the liquid being contained in the cavity of the oscillation chamber form an oscillation system, in which oscillation of the elastically deformable element by the actuator varies pressure inside the cavity, and the actuator being further configured to oscillate the elastically deformable element at a resonant frequency of the oscillation system to eject liquid contained in the cavity from the cavity through the plurality of nozzles of the mesh element. An aerosol-generating system, an aerosol-generating device, and a method of operating an atomiser assembly are also provided.

Abstract: A mesh for an atomizer assembly is provided, including a first surface, a second surface, and a plurality of nozzles extending between the first surface and the second surface, the first surface being at least partially coated with a hydrophilic coating or the second surface being at least partially coated with a hydrophobic coating, the plurality of nozzles defining an inner surface, and the inner surface being at least partially coated with the hydrophilic coating. An atomizer assembly for an aerosol-generating device, and an aerosol-generating device comprising an atomizer assembly, are also provided.

Abstract: A turbine of a turbomachine includes a ceramic matrix composite sector of a stator includes an outer platform and an inner platform connected via at least one vane, The outer platform has means for attaching to a sector of a metallic support, the attachment means having at least one central rim and two lateral rims. The central rim is radially offset with respect to said lateral rims along a directrix line such that the central rim is radially on one side of said directrix line and the lateral rims on the other. The central rim and said central hook bear radially against one another and are located radially on either side of said directrix line. The lateral rim and said corresponding lateral hook bear radially against one another and are located radially on either side of said directrix line.

Abstract: Techniques are included for providing a parallel pseudo infinite timeline monotonic clock that may be used to determine time and durations. A system clock is used to obtain an original time instant that anchors the pseudo infinite timeline to be parallel to a timeline of the system clock. The monotonic clock obtains time ticks from a monotonic tick supplier. The monotonic time ticks are used to determine times and durations, rather than relying on time instants obtained from the system clock. The use of a sliding window anchored at various times allows the parallel timeline to be almost infinite in implementation, rather than wrapping once a maximum value is reached. In addition, the accuracy of computations of time and duration are impervious to changes to the system clock, due to the use of the monotonic time ticks instead of obtaining multiple time instants from the system clock.

Abstract: A mesh element for an atomiser assembly is provided, including: a first layer defining at least one channel including a minimum cross-sectional area; and a second layer overlying the first layer and defining at least one nozzle including a maximum cross-sectional area, the second layer including an inner surface facing the first layer and an outer surface facing away from the first layer, the at least one nozzle overlying the at least one channel, and the maximum cross-sectional area of the at least one nozzle being smaller than the minimum cross-sectional area of the at least one channel, and the outer surface of the second layer defining an annular portion extending around the at least one nozzle, the annular portion having a semi-circular cross-sectional shape, and a thickness of the second layer at each annular portion being larger than a thickness of the second layer between adjacent annular portions.

Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.

Abstract: Systems and methods are provided based on tightly coupled RS flows to provide bi-directional asynchronous stream processing with non-blocking back pressure. Signal, data, and error processing may be performed and routing of signals, data, and error information between multiple RS flows may be performed according to detected conditions.

Abstract: The rotatable machine includes a compressor and an inner annular casing circumscribing at least a portion of the compressor. The inner annular casing includes an outer surface in a radial direction, an upper portion in a vertical direction, and a lower portion in a vertical direction. The clearance control system includes a manifold system including at least one conduit extending circumferentially around the lower portion of the inner annular casing. The clearance control system includes a header system including at least one header extending circumferentially around only the lower portion of the inner annular casing. The at least one header configured to receive a flow of cooling fluid from the at least one conduit. The at least one header configured to channel the flow of cooling fluid to the lower portion of the outer surface of the inner annular casing.

Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosam-ide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenesGrain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appear-ance of resistant mutants compared to commonly used topical antibiotics.

Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

Abstract: Methods, devices, and systems for monitoring a health parameter of a user. A portable monitoring device comprises a housing adapted to couple to a user proximate to the user's respiratory tract; a first audio sensor, disposed in the housing, is adapted to detect a breath sound of the user and create breath sound data; and a processor coupled to the first audio sensor transduces the breath sound data into a modified breath sound signal which is representative of a parameter of the user's breathing, and the processor is adapted to compare the parameter of the user's breathing to a predetermined parameter threshold.

Abstract: Systems and methods are provided based on tightly coupled RS flows to provide bi-directional asynchronous stream processing with non-blocking back pressure. Signal, data, and error processing may be performed and routing of signals, data, and error information between multiple RS flows may be performed according to detected conditions.

Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.