Patents by Inventor Daniel Keeley
Daniel Keeley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10342662Abstract: Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.Type: GrantFiled: September 29, 2017Date of Patent: July 9, 2019Assignee: DePuy Synthes Products, Inc.Inventors: Michael J. O'Neil, Liesbeth Brown, Nimish Parikh, Daniel Keeley, Shannon Cormier
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Publication number: 20180085220Abstract: Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.Type: ApplicationFiled: September 29, 2017Publication date: March 29, 2018Applicant: DePuy Synthes Products, Inc.Inventors: Michael J. O'Neil, Liesbeth Brown, Nimish Parikh, Daniel Keeley, Shannon Cormier
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Patent number: 9801725Abstract: Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.Type: GrantFiled: July 25, 2016Date of Patent: October 31, 2017Assignee: DePuy Synthes Products, Inc.Inventors: Michael J. O'Neil, Liesbeth Brown, Nimish Parikh, Daniel Keeley, Shannon Cormier
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Publication number: 20170049572Abstract: Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.Type: ApplicationFiled: July 25, 2016Publication date: February 23, 2017Applicant: DePuy Synthes Products, Inc.Inventors: Michael J. O'Neil, Liesbeth Brown, Nimish Parikh, Daniel Keeley, Shannon Cormier
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Publication number: 20160081804Abstract: Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.Type: ApplicationFiled: October 7, 2015Publication date: March 24, 2016Applicant: DEPUY SYNTHES PRODUCTS, INC.Inventors: Michael J. O'Neil, Liesbeth Brown, Nimish Parikh, Daniel Keeley
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Patent number: 9168138Abstract: Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.Type: GrantFiled: December 9, 2009Date of Patent: October 27, 2015Assignee: DePuy Synthes Products, Inc.Inventors: Michael J. O'Neil, Liesbeth Brown, Nimish Parikh, Daniel Keeley, Shannon Webster
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Patent number: 8439892Abstract: A therapeutic agent delivery system that includes a catheter having a proximal end and an opposite distal end. The catheter has a body with a lumen defined therein. The body of the catheter includes a non-bulbous region having a substantially uniform outer diameter and a bulbous region made from an elastically deformable material. While in a first state the bulbous region has a maximum outer diameter greater than the substantially uniform outer diameter of the non-bulbous region; and while in a second state the maximum outer diameter of the bulbous region is reduced relative to that while in the first state.Type: GrantFiled: February 25, 2012Date of Patent: May 14, 2013Assignee: Codman & Shurtleff, Inc.Inventors: John R. Hoofnagle, Greg Schorn, Terri Kapur, Daniel Keeley
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Publication number: 20120157921Abstract: A therapeutic agent delivery system that includes a catheter having a proximal end and an opposite distal end. The catheter has a body with a lumen defined therein. The body of the catheter includes a non-bulbous region having a substantially uniform outer diameter and a bulbous region made from an elastically deformable material. While in a first state the bulbous region has a maximum outer diameter greater than the substantially uniform outer diameter of the non-bulbous region; and while in a second state the maximum outer diameter of the bulbous region is reduced relative to that while in the first state.Type: ApplicationFiled: February 25, 2012Publication date: June 21, 2012Applicant: Codman & Shurtleff, Inc.Inventors: John R. Hoofnagle, Greg Schorn, Terri Kapur, Daniel Keeley
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Patent number: 8147480Abstract: A therapeutic agent delivery system that includes a catheter having a proximal end and an opposite distal end. The catheter has a body with a lumen defined therein. The body of the catheter includes a non-bulbous region having a substantially uniform outer diameter and a bulbous region made from an elastically deformable material. While in a first state the bulbous region has a maximum outer diameter greater than the substantially uniform outer diameter of the non-bulbous region; and while in a second state the maximum outer diameter of the bulbous region is reduced relative to that while in the first state.Type: GrantFiled: June 7, 2008Date of Patent: April 3, 2012Assignee: Codman & Shurtleff, Inc.Inventors: John R. Hoofnagle, Schorn Greg, Terri Kapur, Daniel Keeley
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Publication number: 20110137418Abstract: Devices and methods for in situ drawing, filtering and seeding cells from the marrow of surrounding bone into a fusion cage without any of the challenges mentioned above. Various implants and devices with aspiration ports that enable in-situ harvesting and mixing of stem cells. These devices may include spinal fusion cages, long bone spacers, lateral grafts and joint replacement devices. Each device utilizes at least one aspiration port for harvesting of stem cell-containing marrow via aspiration from adjacent bony elements.Type: ApplicationFiled: December 9, 2009Publication date: June 9, 2011Inventors: Michael J. O'Neil, Liesbeth Brown, Nimish Parikh, Daniel Keeley, Shannon Webster
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Patent number: 7766875Abstract: A catheter for delivery of a therapeutic agent directly into a targeted tissue that reduces or substantially prevents reflux and back flow by providing rigidity and strength via a stylet thereby eliminating the need for a guide or delivery sheath during positioning. The catheter has a flexible proximal section and a substantially rigid distal section formed from a plurality of distal subsections. The proximal and distal sections having decreasing outer diameters starting from the proximal end and advancing towards the distal end. The distal subsection closest to the distal end providing an adjustable flow rate via multiple output ports defined radially therein while the distal end itself is closed off.Type: GrantFiled: September 28, 2007Date of Patent: August 3, 2010Assignee: Codman & Shurtleff, Inc.Inventors: Terri Kapur, Daniel Keeley, Greg Schorn
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Publication number: 20090088695Abstract: A catheter for delivery of a therapeutic agent directly into a targeted tissue that reduces or substantially prevents reflux and back flow by providing rigidity and strength via a stylet thereby eliminating the need for a guide or delivery sheath during positioning. The catheter has a flexible proximal section and a substantially rigid distal section formed from a plurality of distal subsections. The proximal and distal sections having decreasing outer diameters starting from the proximal end and advancing towards the distal end. The distal subsection closest to the distal end providing an adjustable flow rate via multiple output ports defined radially therein while the distal end itself is closed off.Type: ApplicationFiled: September 28, 2007Publication date: April 2, 2009Applicant: Codman & Shurtleff, Inc.Inventors: Terri Kapur, Daniel Keeley, Greg Schorn
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Publication number: 20090088730Abstract: A therapeutic agent delivery system that includes a catheter having a proximal end and an opposite distal end. The catheter has a body with a lumen defined therein. The body of the catheter includes a non-bulbous region having a substantially uniform outer diameter and a bulbous region made from an elastically deformable material. While in a first state the bulbous region has a maximum outer diameter greater than the substantially uniform outer diameter of the non-bulbous region; and while in a second state the maximum outer diameter of the bulbous region is reduced relative to that while in the first state.Type: ApplicationFiled: June 7, 2008Publication date: April 2, 2009Applicant: Codman & Shurtleff, Inc.Inventors: John R. Hoofnagle, Greg Schorn, Terri Kapur, Daniel Keeley
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Publication number: 20090075371Abstract: The invention relates generally to devices for organ replacement and regenerative medicine providing a biocompatible and biodegradable scaffold capable of integral cell growth that forms a hollow chamber, as well as methods for producing such devices by lyophilizing biocompatible, biodegradable polymers to produce a seamless, three-dimensional shape.Type: ApplicationFiled: September 18, 2007Publication date: March 19, 2009Inventors: Daniel Keeley, Dhanuraj Shetty, Joseph J. Hammer, Ziwei Wang
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Publication number: 20080081362Abstract: The present invention relates to devices and methods for tissue augmentation or regeneration and specifically, to a composite of bioabsorbable scaffold material and autologous tissue, suitable for implantation in tissue or organs.Type: ApplicationFiled: September 18, 2007Publication date: April 3, 2008Inventors: Daniel Keeley, Dhanuraj Shetty, Sridevi Dhanaraj, Ziwei Wang
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Publication number: 20080081323Abstract: The invention relates generally to devices for organ replacement and regenerative medicine providing a biocompatible and biodegradable scaffold capable of integral cell growth that forms a hollow chamber, as well as methods for producing such devices by melt-blowing a web of flexible, polymer fibers in the presence of a porogen to produce a seamless, three-dimensional shape.Type: ApplicationFiled: September 18, 2007Publication date: April 3, 2008Inventors: Daniel Keeley, Dhanuraj Shetty, Joseph J. Hammer