Abstract: An example of a method includes providing a substrate with an exposed surface comprising a first chemical group, wherein the providing optionally comprises modifying the exposed surface of the substrate to incorporate the first chemical group; reacting the first chemical group with a first reactive group of a functionalized polymer molecule to form a functionalized polymer coating layer covalently bound to the exposed surface of the substrate; grafting a primer to the functionalized polymer coating layer by reacting the primer with a second reactive group of the functionalized polymer coating layer; and forming a water-soluble protective coating on the primer and the functionalized polymer coating layer. Examples of flow cells incorporating examples of the water-soluble protective coating are also disclosed herein.

Abstract: The present invention relates to a Plasmid Addiction System for the stabilization of expression plasmids encoding proteins of interest. The invention uses a succinate cycle optimization to ensure the expression of plasmid(s) of interest. By ensuring that plasmids of interest contain genes necessary in the succinate cycle, the system ensures that the passage of the plasmid to daughters and therefore improves the efficiency of production and expression of genes and/or products of interest.

Abstract: Provided herein are radiopharmaceutical compositions and uses thereof. The radiopharmaceutical compositions can comprise one or more stabilizing agents, an aqueous vehicle, and a conjugate that comprises a targeting ligand and a radionuclide bound to a metal chelator. The targeting ligand can be a small molecule compound or a peptide such as a monocyclic peptide. The targeting ligand can be configured to bind with a tumor target. The stabilizing agent can comprise a radiolysis stabilizer, a free metal chelator, and/or a pH stabilizer. Further provided herein are methods of preparing the radiopharmaceutical compositions and methods of treating cancer by administering the described radiopharmaceutical compositions.

Abstract: Methods, systems, and computer program products for gathering electronic signatures to be applied to collaboration system content objects (e.g., contracts, letters, insurance claims, riders, etc.). A collaboration system monitors changes made to the collaboration system content objects during electronic signature processing. A module of the content management system is configured to associate one or more instances of e-signing metadata to one or more of the stored content objects of the content management system. The e-signing metadata indicates whether or not a particular portion of the one or more of the stored content objects has been e-signed by a designated e-signatory. A collaborator who is not one of the designated e-signatories makes a change to one or more of the stored content objects (e.g., contracts, letters, insurance claims, riders, etc.). The change is remediated on-the-fly and the e-signing process continues without having to restart the e-signing process from the beginning.

Abstract: In some implementations, a network device includes a housing and a set of switch cards within the housing and including a first set of connectors. A set of line cards within the housing includes a second set of connectors. The set of line cards are oriented orthogonally to the set of switch cards. A first set of power supplies and a second set of power supplies are in the housing. A midplane includes a plurality of circuit board assemblies arranged within the housing between the set of line cards and the first and second sets of power supplies to allow air to flow through the set of line cards to the set of switch cards, first set of power supplies, and second set of power supplies.

Abstract: Provided herein are radiopharmaceutical compositions and uses thereof. The radiopharmaceutical compositions can comprise one or more stabilizing agents, an aqueous vehicle, and a conjugate that comprises a targeting ligand and a radionuclide bound to a metal chelator. The targeting ligand can be a small molecule compound or a peptide such as a monocyclic peptide. The targeting ligand can be configured to bind with a tumor target. The stabilizing agent can comprise a radiolysis stabilizer, a free metal chelator, and/or a pH stabilizer. Further provided herein are methods of preparing the radiopharmaceutical compositions and methods of treating cancer by administering the described radiopharmaceutical compositions.

Abstract: Provided herein are radiopharmaceutical compositions and uses thereof. The radiopharmaceutical compositions can comprise one or more stabilizing agents, an aqueous vehicle, and a conjugate that comprises a targeting ligand and a radionuclide bound to a metal chelator. The targeting ligand can be a small molecule compound or a peptide such as a monocyclic peptide. The targeting ligand can be configured to bind with a tumor target. The stabilizing agent can comprise a radiolysis stabilizer, a free metal chelator, and/or a pH stabilizer. Further provided herein are methods of preparing the radiopharmaceutical compositions and methods of treating cancer by administering the described radiopharmaceutical compositions.

Abstract: Aspects relate to providing an efficient way to claim a non-fungible token (NFT) associated with a physical object, such as a merchandise item. A user device may scan, using a scanning device, for access information of a physical object, and determine a link to an NFT associated with the physical object based on the scanned access information. Subsequently, the user device may transmit, to an NFT server device, an NFT command indicating the link and a user account of a user to cause the NFT to be claimed by the user account. Other aspects, embodiments, and features are also claimed and described.

Abstract: The present invention relates to a Plasmid Addiction System for the stabilization of expression plasmids encoding proteins of interest. The invention uses a succinate cycle optimization to ensure the expression of plasmid(s) of interest. By ensuring that plasmids of interest contain genes necessary in the succinate cycle, the system ensures that the passage of the plasmid to daughters and therefore improves the efficiency of production and expression of genes and/or products of interest.

Abstract: The present invention relates to a Plasmid Addiction System for the stabilization of expression plasmids encoding proteins of interest. The invention uses a succinate cycle optimization to ensure the expression of plasmid(s) of interest. By ensuring that plasmids of interest contain genes necessary in the succinate cycle, the system ensures that the passage of the plasmid to daughters and therefore improves the efficiency of production and expression of genes and/or products of interest.

Abstract: An approach is disclosed for generating an adjustable ruleset for fingerprinting data. The approach involves, for example, designating a data type as private. The approach also involves collecting private data relating to user from one or more data sources, wherein the private data includes a plurality of attributes that include a private attribute having the private data type. The approach further involves transforming the private attribute based on one or more configured rules for tokenizing the private attribute. The approach also involves generating a token corresponding to transformed private attribute; and initiating storage of the token for subsequent discovery of data having the private data type.

Abstract: The present application discloses a pad structure that includes a stretchable cuttable material with beveled edge.

Abstract: A method of operating a storage system may include allocating a first partition of a tier of storage resources to a first client, wherein the tier operates at least partially as a storage cache, allocating a second partition of the tier of the storage resources to a second client, monitoring a workload of the first client, monitoring a workload of the second client, and reallocating the first partition of the tier of the storage resources to the first client based on the monitored workload of the first client and the monitored workload of the second client. The method may further include reallocating the second partition of the tier of the storage resources to the second client based on the monitored workload of the first client and the monitored workload of the second client.

Abstract: In one embodiment a device for tightening and loosening a securing device is provided. The device includes a housing, a shaft, and a clutch assembly. In one embodiment, the clutch assembly includes a clutch activation member, a first friction member coupled to the clutch activation member, and a second friction member coupled to the shaft. When the clutch activation member is in a first position, the clutch activation member engages the first friction member with the second friction member for transmission of torque from the first friction member to the second friction member. When the clutch activation member is in the second position, the clutch activation member disengages the first friction member from the second friction member to prevent transmission of the torque from the first friction member to the second friction member.

Abstract: An imaging system includes a sensor configured to receive imaging data, where the imaging data comprises k-space data from a magnetic resonance imaging (MRI) scan of a patient. The imaging system also includes a processor operatively coupled to the sensor and configured to identify a degree of interaction between measured points of the k-space data located at a radius from a center of k-space. The processor is also configured to determine, based at least in part on the degree of interaction between the measured points, density weights for a density compensation filter. The processor is also configured to apply the density compensation filter to the k-space data to generate filtered k-space data. The processor is further configured to generate an MRI image of the patient based at least in part on the filtered k-space data.

Abstract: In one embodiment a device for tightening and loosening a securing device is provided. The device includes a housing, a shaft, and a clutch assembly. In one embodiment, the clutch assembly includes a clutch activation member, a first friction member coupled to the clutch activation member, and a second friction member coupled to the shaft. When the clutch activation member is in a first position, the clutch activation member engages the first friction member with the second friction member for transmission of torque from the first friction member to the second friction member. When the clutch activation member is in the second position, the clutch activation member disengages the first friction member from the second friction member to prevent transmission of the torque from the first friction member to the second friction member.

Abstract: In one embodiment, a method includes identifying a pre-determined number of items associated with one or more entities; transmitting item information associated with the pre-determined number of items to a client device; and determining that the client device is likely to enter a first entity of the one or more entities. The first entity is identified based on a physical proximity between the client device and the first entity. The method also includes accessing, based on the first entity, location-specific item information associated with one or more of the pre-determined number of items or one or more additional items; and transmitting the location-specific item information to the client device. The item information and the location-specific item information are configured to be used by the client device while the client device is within the first entity.

Abstract: A method, a machine-readable storage medium and at least one processing device are provided for analyzing and tracking results of multiple conditions associated with a population criteria, which is evaluated for each entity of at least one entity. The at least one processing device performs analytics associated with the population criteria, which is evaluated for each entity. Results of the analyzing of the multiple conditions are selectively tracked by the at least one processing device. The at least one processing device presents the tracked results to indicate a status of the at least one entity with respect to the tracked analytics.

Abstract: A method, a machine-readable storage medium and at least one processing device are provided for analyzing and tracking results of multiple conditions associated with a population criteria, which is evaluated for each entity of at least one entity. The at least one processing device performs analytics associated with the population criteria, which is evaluated for each entity. Results of the analyzing of the multiple conditions are selectively tracked by the at least one processing device. The at least one processing device presents the tracked results to indicate a status of the at least one entity with respect to the tracked analytics.

Abstract: In some implementations, a network device includes a housing and a set of switch cards within the housing and including a first set of connectors. A set of line cards within the housing includes a second set of connectors. The set of line cards are oriented orthogonally to the set of switch cards. A first set of power supplies and a second set of power supplies are in the housing. A midplane includes a plurality of circuit board assemblies arranged within the housing between the set of line cards and the first and second sets of power supplies to allow air to flow through the set of line cards to the set of switch cards, first set of power supplies, and second set of power supplies.