Patents by Inventor Daniel Kopetzki

Daniel Kopetzki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives
    Patent number: 9802952
    Abstract: The present invention is directed to a method for continuous production of dihydroartemisinin and also artemisinin derivatives derived from dihydroartemisinin by using artemisinin or dihydroartemisinic acid (DHAA) as starting material as well as to a continuous flow reactor for producing dihydroartemisinin as well as the artemisinin derivatives. It was found that the reduction of artemisinin to dihydroartemisinin in a continuous process requires a special kind of reactor and a special combination of reagents comprising a hydride reducing agent, at least one activator such as an inorganic activator, at least one solid base, at least one aprotic solvent and at least one C1-C5 alcohol.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: October 31, 2017
    Assignee: Max-Plank-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Daniel Kopetzki, David Tyler McQuade, Peter H. Seeberger, Kerry Gilmore
  • Method and device for the synthesis of artemisinin
    Patent number: 9409142
    Abstract: The present invention is directed to a method for producing artemisinin having the formula from dihydroartemisinic acid in a continuous flow reactor using singlet oxygen as well as to the continuous flow reactor for producing artemisinin.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: August 9, 2016
    Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Peter H. Seeberger, Daniel Kopetzki, Francois Lévesque
  • METHOD AND APPARATUS FOR THE SYNTHESIS OF DIHYDROARTEMISININ AND ARTEMISININ DERIVATIVES
    Publication number: 20160145265
    Abstract: The present invention is directed to a method for continuous production of dihydroartemisinin and also artemisinin derivatives derived from dihydroartemisinin by using artemisinin or dihydroartemisinic acid (DHAA) as starting material as well as to a continuous flow reactor for producing dihydroartemisinin as well as the artemisinin derivatives. It was found that the reduction of artemisinin to dihydroartemisinin in a continuous process requires a special kind of reactor and a special combination of reagents comprising a hydride reducing agent, at least one activator such as an inorganic activator, at least one solid base, at least one aprotic solvent and at least one C1-C5 alcohol.
    Type: Application
    Filed: July 14, 2014
    Publication date: May 26, 2016
    Inventors: Daniel Kopetzki, David Tyler McQuade, Peter H. Seeberger, Kerry Gilmore
  • METHOD AND DEVICE FOR THE SYNTHESIS OF ARTEMISININ
    Publication number: 20150328617
    Abstract: The present invention is directed to a method for producing artemisinin having the formula from dihydroartemisinic acid in a continuous flow reactor using singlet oxygen as well as to the continuous flow reactor for producing artemisinin.
    Type: Application
    Filed: July 28, 2015
    Publication date: November 19, 2015
    Inventors: Peter H. Seeberger, Daniel Kopetzki, Francois Lévesque
  • Method and device for the synthesis of artemisinin
    Patent number: 9150535
    Abstract: The present invention is directed to a method for producing artemisinin having the formula from dihydroartemisinic acid in a continuous flow reactor using singlet oxygen as well as to the continuous flow reactor for producing artemisinin.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: October 6, 2015
    Assignee: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Peter H. Seeberger, Daniel Kopetzki, Francois Levesque
  • METHOD AND DEVICE FOR THE SYNTHESIS OF ARTEMISININ
    Publication number: 20140364630
    Abstract: The present invention is directed to a method for producing artemisinin having the formula from dihydroartemisinic acid in a continuous flow reactor using singlet oxygen as well as to the continuous flow reactor for producing artemisinin.
    Type: Application
    Filed: August 29, 2012
    Publication date: December 11, 2014
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSC
    Inventors: Peter H. Seeberger, Daniel Kopetzki, Francois Levesque
  • CATANIONIC VESICLES, PROCESS FOR PREPARING SAME AND APPLICATIONS THEREOF
    Publication number: 20110253633
    Abstract: Catanionic vesicles, the walls of which are constituted of a mixture of surfactants of opposite charges. Process for preparing same and uses thereof, especially in the field of pharmacy or cosmetics, in the sector for the pollution control of aqueous media or in the field of the synthesis of nanoparticles.
    Type: Application
    Filed: October 20, 2009
    Publication date: October 20, 2011
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALT.
    Inventors: David Carriere, Youlia Michina, Daniel Kopetzki