Abstract: Cleaning systems and methods include use of a container or holding apparatus to receive one or more components used in a medical procedure (e.g., a walled container or a non-walled container including a plurality of holding structures) and a manifold apparatus. For example, the manifold apparatus may include an inlet connection connectable to a reprocessor fitting of a reprocessing apparatus to receive a fluid therefrom (e.g., a cleaning solution, a disinfecting solution, and a rinsing solution) and one or more outlets configured to provide the at least one fluid into or through one or more components received by the container. For example, the one or more outlets may include an outlet connection connectable to a component fitting of at least one of the components.