Patents by Inventor Daniel M. Storey
Daniel M. Storey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240132825Abstract: The invention discloses a quasi in-vivo testing method using a uniquely designed multichambered bioblock apparatus. Cells are placed inside a top chamber fitted with a pore size membrane that allows certain cells to migrate through the pores into a bottom chamber holding a substrate. The portion of cells migrating from the top chamber and interacting with the substrate surface in a real time physiological quasi in vivo environment can be used to determine both the migratory response of specific cell types to selected attractive surfaces and the effect of the migratory cells on the surface over selected times of exposure.Type: ApplicationFiled: October 18, 2023Publication date: April 25, 2024Inventors: DANIEL M. STOREY, CHRISTINA K. THOMAS, SIENNA PEARL STOLL
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Patent number: 11306389Abstract: The invention is directed to an ion plasma deposition (IPD) method adapted to coat polymer surfaces with highly adherent antimicrobial films. A controlled ion plasma deposition (IPD) process is used to coat a metal or polymer with a selected metal/metal oxide. Exposing the coated surface to ultraviolet light significantly improves the antimicrobial properties of the deposited coatings.Type: GrantFiled: April 30, 2019Date of Patent: April 19, 2022Assignee: METASCAPE LLCInventors: Terrence S. Mcgrath, Deidre Sewell, Daniel M. Storey
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Publication number: 20190374677Abstract: The invention relates to bioactive surface coatings deposited on selected substrates. Surface nanostructured film coatings deposited on most metal or nonmetal substrates to provide surfaces can be engineered to promote enhanced tissue/cell adhesion. Attached cells, including osteoblasts, fibroblasts and endothelial cells, retain viability and will readily differentiate and proliferate under appropriate conditions. Fibroblasts and endothelial cells exhibit good attachment and growth on most coated substrates, except on nano surfaced structured silicone.Type: ApplicationFiled: August 6, 2019Publication date: December 12, 2019Inventors: DANIEL M. STOREY, TERRENCE S. MCGRATH, ALEXANDER B. REISING
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Publication number: 20190255225Abstract: The invention is directed to an ion plasma deposition (IPD) method adapted to coat polymer surfaces with highly adherent antimicrobial films. A controlled ion plasma deposition (IPD) process is used to coat a metal or polymer with a selected metal/metal oxide. Exposing the coated surface to ultraviolet light significantly improves the antimicrobial properties of the deposited coatings.Type: ApplicationFiled: April 30, 2019Publication date: August 22, 2019Inventors: TERRENCE S. MCGRATH, DEIDRE SEWELL, DANIEL M. STOREY
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Publication number: 20180010236Abstract: Nanostructured surfaces on selected substrates are described which are highly resistant to cell adhesion. Such surfaces on medical implants inhibit fibroblast adhesion particularly on nanorough titanium deposited on smooth silicone surfaces. The nanostructured deposited metal coatings can also be engineered so that several cell types, including endothelial, osteoblast, and fibroblast cells, show little if any tendency to attach to the coated surface in vivo.Type: ApplicationFiled: August 29, 2017Publication date: January 11, 2018Inventors: DANIEL M. STOREY, LUKE J. RYVES, BARBARA S. KITCHELL
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Publication number: 20170112962Abstract: The invention relates to bioactive surface coatings deposited on selected substrates. Surface nanostructured film coatings deposited on most metal or nonmetal substrates to provide surfaces can be engineered to promote enhanced tissue/cell adhesion. Attached cells, including osteoblasts, fibroblasts and endothelial cells, retain viability and will readily differentiate and proliferate under appropriate conditions. Fibroblasts and endothelial cells exhibit good attachment and growth on most coated substrates, except on nano surfaced structured silicone.Type: ApplicationFiled: January 6, 2017Publication date: April 27, 2017Inventors: DANIEL M. STOREY, TERRENCE S. MCGRATH, ALEXANDER B. REISING
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Publication number: 20160287760Abstract: The invention is directed to an ion plasma deposition (IPD) method adapted to coat polymer surfaces with highly adherent antimicrobial films. A controlled ion plasma deposition (IPD) process is used to coat a metal or polymer with a selected metal/metal oxide. Exposing the coated surface to ultraviolet light significantly improves the antimicrobial properties of the deposited coatings.Type: ApplicationFiled: June 14, 2016Publication date: October 6, 2016Inventors: TERRENCE S. MCGRATH, DEIDRE SEWELL, DANIEL M. STOREY
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Patent number: 9422622Abstract: Thin conductive metal coatings suitable for flexible nonmetal fine wires and leads are described. Polymer clad silica fiber cores are produced by plasma coating with single or dual layers of metals such as silver, gold or titanium to provide micro thin leads such as those used for pacemakers and fracture resistant aircraft wires that are both conductive and resistant to flexing breakage. The metal surfaces can be used to transmit analog signals while the nonmetal cores can be designed to transmit digital signals. Select deposition conditions can produce nanorough metal coating surfaces which promote cell adhesion so that tissue scarring in vivo is greatly reduced.Type: GrantFiled: October 3, 2012Date of Patent: August 23, 2016Assignee: SURFATEK LLCInventor: Daniel M. Storey
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Patent number: 9393350Abstract: The invention is directed to an ion plasma deposition (IPD) method adapted to coat polymer surfaces with highly adherent antimicrobial films. A controlled ion plasma deposition (IPD) process is used to coat a metal or polymer with a selected metal/metal oxide. Exposing the coated surface to ultraviolet light significantly improves the antimicrobial properties of the deposited coatings.Type: GrantFiled: January 7, 2014Date of Patent: July 19, 2016Inventors: Terrence S. McGrath, Deidre Sewell, Daniel M. Storey
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Publication number: 20140127391Abstract: The invention is directed to an ion plasma deposition (IPD) method adapted to coat polymer surfaces with highly adherent antimicrobial films. A controlled ion plasma deposition (IPD) process is used to coat a metal or polymer with a selected metal/metal oxide. Exposing the coated surface to ultraviolet light significantly improves the antimicrobial properties of the deposited coatings.Type: ApplicationFiled: January 7, 2014Publication date: May 8, 2014Applicant: METASCAPE, LLCInventors: TERRENCE S. MCGRATH, DEIDRE SEWELL, DANIEL M. STOREY
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Patent number: 8623446Abstract: The invention is directed to an ion plasma deposition (IPD) method adapted to coat polymer surfaces with highly adherent antimicrobial films. A controlled ion plasma deposition (IPD) process is used to coat a metal or polymer with a selected metal/metal oxide. Exposing the coated surface to ultraviolet light significantly improves the antimicrobial properties of the deposited coatings.Type: GrantFiled: October 3, 2006Date of Patent: January 7, 2014Assignee: Metascape LLCInventors: Terrence S. McGrath, Deidre Sewell, Daniel M. Storey
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Publication number: 20130053938Abstract: A molecular plasma deposition (MPD) method in combination with an atomic layer deposition (ALD) procedure is used to produce amorphous, nonconformal thin metal film coatings on a variety of substrates. The films are porous, mesh-like lattices with imperfections such as pinholes and pores, which are useful as scaffolds for cell attachment, controlled release of bioactive agents and protective coatings.Type: ApplicationFiled: August 1, 2012Publication date: February 28, 2013Applicant: METASCAPE LLCInventors: Tiffany E. Miller, Daniel M. Storey, Barbara S. Kitchell
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Publication number: 20130046368Abstract: Thin conductive metal coatings suitable for flexible nonmetal fine wires and leads are described. Polymer clad silica fiber cores are produced by plasma coating with single or dual layers of metals such as silver, gold or titanium to provide micro thin leads such as those used for pacemakers and fracture resistant aircraft wires that are both conductive and resistant to flexing breakage. The metal surfaces can be used to transmit analog signals while the nonmetal cores can be designed to transmit digital signals. Select deposition conditions can produce nanorough metal coating surfaces which promote cell adhesion so that tissue scarring in vivo is greatly reduced.Type: ApplicationFiled: October 3, 2012Publication date: February 21, 2013Inventor: DANIEL M. STOREY
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Patent number: 8158216Abstract: Vapor plasma deposition of titanium (Ti) metal onto a substrate forms a structured surface that exhibits enhanced cell attachment properties. Initially deposited round nanoparticulate surface structures develop tentacles with a spine or thorn-like appearance upon continued deposition under special conditions. The density and size of the formed spinulose particles can be controlled by timing the deposition intervals. A significant increase in osteoblast, fibroblast and endothelial cell attachment is observed on Ti spinulose surfaces compared to attachment on nanoparticulate surfaces lacking spinulous nanostructure.Type: GrantFiled: October 31, 2007Date of Patent: April 17, 2012Assignee: Metascape LLCInventors: Christina Kay Thomas, Luke J. Ryves, Daniel M. Storey
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Patent number: 8066854Abstract: The invention is directed to efficient methods for depositing highly adherent anti-microbial materials onto a wide range of surfaces. A controlled cathodic arc process is described, which results in enhanced adhesion of silver oxide to polymers and other surfaces, such as surfaces of medical devices. Deposition of anti-microbial materials directly onto the substrates is possible in a cost-effective manner that maintains high anti-microbial activity over several weeks when the coated devices are employed in vivo.Type: GrantFiled: April 19, 2006Date of Patent: November 29, 2011Assignee: Metascape LLCInventors: Daniel M. Storey, Deidre Sewell, Terrence S. McGrath, John H. Petersen
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Patent number: 7920369Abstract: An apparatus and method for initiation and control of a sustained metal plasma and nano plasma (macroparticulate) deposition methods for preparing modified metal coatings are provided. The plasma deposition process can be tightly controlled by virtue of a device that incorporates a plasma arc initiator component and an internal power supply that is capable of controlling dwell time on the target and the size range of particles ejected in the plasma arc.Type: GrantFiled: January 23, 2007Date of Patent: April 5, 2011Assignee: Metascape, LLC.Inventor: Daniel M. Storey
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Publication number: 20110054633Abstract: A modified atomic plasma deposition (APD) procedure is used to produce amorphous, nonconformal thin metal film coatings on a variety of substrates. The films are porous, mesh-like lattices with imperfections such as pinholes and pores, which are useful as scaffolds for cell attachment, controlled release of bioactive agents and protective coatings.Type: ApplicationFiled: December 18, 2008Publication date: March 3, 2011Applicant: NANOSURFACE TECHNOLOGIES, LLCInventors: Tiffany E. Miller, Daniel M. Storey, Barbara S. Kitchell
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Publication number: 20110003172Abstract: Vapor plasma deposition of titanium (Ti) metal onto a substrate forms a structured surface that exhibits enhanced cell attachment properties. Initially deposited round nanoparticulate surface structures develop tentacles with a spine or thorn-like appearance upon continued deposition under special conditions. The density and size of the formed spinulose particles can be controlled by timing the deposition intervals. A significant increase in osteoblast, fibroblast and endothelial cell attachment is observed on Ti spinulose surfaces compared to attachment on nanoparticulate surfaces lacking spinulous nanostructure.Type: ApplicationFiled: October 31, 2007Publication date: January 6, 2011Inventors: Christina Kay Thomas, Luke J. Ryves, Daniel M. Storey
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Publication number: 20100298925Abstract: Spinulose metal surfaces are produced by a modified nanoplasma cyclic deposition process. The unique spinulose surfaces are highly adherent toward polymer and bioactive molecules and cells, including osteoblast, fibroblast and endothelial cells. The nanostructured spinulose surfaces can be coated with a wide range of polymers to form polymer surface coatings that are particularly useful on implants, catheters, guidewires, stents and other medical devices intended for in vivo applications.Type: ApplicationFiled: June 16, 2010Publication date: November 25, 2010Applicant: CHAMELEON SCIENTIFIC CORPORATIONInventors: CHRISTINA K. THOMAS, DANIEL M. STOREY
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Publication number: 20100204777Abstract: Nanostructured surfaces on selected substrates are described which are highly resistant to cell adhesion. Such surfaces on medical implants inhibit fibroblast adhesion particularly on nanorough titanium deposited on smooth silicone surfaces. The nanostructured deposited metal coatings can also be engineered so that several cell types, including endothelial, osteoblast, and fibroblast cells, show little if any tendency to attach to the coated surface in vivo.Type: ApplicationFiled: February 16, 2010Publication date: August 12, 2010Applicant: CHAMELEON SCIENTIFIC CORPORATIONInventors: Daniel M. Storey, Luke J. Ryves, Barbara S. Kitchell