Patents by Inventor Daniel P. Rubinstein

Daniel P. Rubinstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel method to sterilize recombinant products
    Publication number: 20030068809
    Abstract: Recombinant proteins, manufactured with genetic engineering techniques, like its counterpart human derived proteins, for example, recombinant Factor VIII have the potential for transmission of viruses and bacteria which are used in the process. This invention demonstrates that one may dry heat at high temperature, the lyophilized final Factor VIII product even at high temperatures and still show significant VIII:C activity. Such terminal dry heat will assure that there has been recontamination.
    Type: Application
    Filed: November 8, 2002
    Publication date: April 10, 2003
    Inventors: Alan I Rubinstein, Daniel P. Rubinstein
  • Novel method to sterilize recombinant products
    Publication number: 20010007766
    Abstract: Recombinant proteins, manufactured with genetic engineering techniques, like its counterpart human derived proteins, for example, recombinant Factor VIII have the potential for transmission of viruses and bacteria which are used in the process. This invention demonstrates that one may dry heat at high temperature, the lyophilized final Factor VIII product even at high temperatures and still show significant VIII:C activity. Such terminal dry heat will assure that there has been recontamination.
    Type: Application
    Filed: February 28, 2001
    Publication date: July 12, 2001
    Inventors: Alan I. Rubinstein, Daniel P. Rubinstein