Patents by Inventor Daniel Robinson

Daniel Robinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminopyrimidines useful as kinase inhibitors
    Patent number: 8637511
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: January 28, 2014
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Michael Mortimore, Chris Davis, Dean Boyall, Simon Everitt, Daniel Robinson, Sham Ramaya, Damien Fraysse, John Studley, Andrew Miller, Michael O'Donnell, Alistair Rutherford, Joanne Pinder
  • AZAINDOLES USEFUL AS INHIBITORS OF JAK AND OTHER PROTEIN KINASES
    Publication number: 20130345197
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: June 3, 2013
    Publication date: December 26, 2013
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Francesco Salituro, Luc Farmer, Randy Bethiel, Edmund Harrington, Jeremy Green, John Court, Jon Come, David Lauffer, Alex Aronov, Hayley Binch, Dean Boyall, Jean-Damien Charrier, Simon Everitt, Damien Fraysse, Michael Mortimore, Francoise Pierard, Daniel Robinson, Jian Wang, Joanne Pinder, Tiansheng Wang, Albert Pierce
  • Providing persistent refined intermediate results selected from dynamic iterative filtering
    Patent number: 8521711
    Abstract: A persistent filter refining system places a search result comprising objects in a dynamic non-persistent bucket and displays the search result in a dynamic non-persistent bucket display for selection of the objects by a user. The system transfers a selected object from the dynamic non-persistent bucket to a persistent bucket and displays the transferred selected object in a persistent bucket display. The system iteratively provides additional search results to the user for selection and transfer of additional selected objects to the persistent bucket to provide access by a user to take action on the transferred selected object and additional selected objects. In one embodiment, the present system displays one or more additional search results for comparison and selection of objects by the user.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: August 27, 2013
    Assignee: International Business Machines Corporation
    Inventors: Tanya Couch, Farnaz Erfan, Thomas Friedrich, Daina Edvina Pupons Wickham, Alexander Daniel Robinson
  • Azaindoles useful as inhibitors of JAK and other protein kinases
    Patent number: 8501446
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: August 6, 2013
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Francesco Salituro, Luc Farmer, Randy Bethiel, Edmund Harrington, Jeremy Green, John Court, Jon Come, David Lauffer, Alex Aronov, Hayley Binch, Dean Boyall, Jean-Damien Charrier, Simon Everitt, Damien Fraysse, Michael Mortimore, Francoise Pierard, Daniel Robinson, Jian Wang, Joanne Pinder, Tiansheng Wang, Albert Pierce
  • THIAZOLES AND PYRAZOLES USEFUL AS KINASE INHIBITORS
    Publication number: 20130116228
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Application
    Filed: August 2, 2012
    Publication date: May 9, 2013
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Michael Mortimore, Julian Golec, Christopher Davis, Daniel Robinson, John Studley
  • PYRROLOPYRAZINES AND PYRAZOLOPYRAZINES USEFUL AS INHIBITORS OF PROTEIN KINASES
    Publication number: 20130096302
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
    Type: Application
    Filed: October 12, 2012
    Publication date: April 18, 2013
    Inventors: Hayley Binch, Daniel Robinson, Damien Fraysse, Andrew Miller
  • THIAZOLES, IMIDAZOLES, AND PYRAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES
    Publication number: 20130090479
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and the compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions.
    Type: Application
    Filed: July 3, 2012
    Publication date: April 11, 2013
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Juan-Miguel Jimenez, Ronald Knegtel, Daniel Robinson, Philip Collier
  • Aminopyrimidines useful as kinase inhibitors
    Patent number: 8383633
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: February 26, 2013
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Michael Mortimore, Julian Golec, Daniel Robinson, John Studley
  • Pyrrolopyrazines and pyrazolopyrazines useful as inhibitors of protein kinases
    Patent number: 8372835
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: February 12, 2013
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Daniel Robinson, Damien Fraysse, Andrew Miller
  • SOUND BARRIERS MADE FROM SCRAP AND WASTE MATERIALS
    Publication number: 20120325579
    Abstract: Sound barrier panels that are made from various waste materials, including scrap fiberglass reinforced plastic (FRP), scrap carpet fibers, recyclable plastics and mineral wool.
    Type: Application
    Filed: June 25, 2012
    Publication date: December 27, 2012
    Inventors: Gregory Smith, Anthony J. Kriech, Daniel Robinson, Matthew Kriech
  • Compositions for importing biologically active molecules into cells
    Patent number: 8324148
    Abstract: The present invention relates to the delivery of biologically active molecules, such as peptides, nucleic acids and therapeutic agents, into the interior of cells by administering to the cells a complex comprising the molecule linked to an importation competent signal peptide. Such delivery can be utilized for purposes such as peptide therapy, gene transfer, and antisense therapy to regulate and/or eradicate systemic inflammatory response syndromes such as endotoxic shock.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: December 4, 2012
    Assignee: Vanderbilt University
    Inventors: Jack J. Hawiger, Daniel Robinson, Ruth Ann Veach, Xue Yan Liu, Danya Liu, Sheila Downs, Robert D. Collins, Yao-Zhong Lin
  • AZAINDOLES USEFUL AS INHIBITORS OF JAK AND OTHER PROTEIN KINASES
    Publication number: 20120258958
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: April 6, 2012
    Publication date: October 11, 2012
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Francesco Salituro, Luc Farmer, Randy Bethiel, Edmund Harrington, Jeremy Green, John Court, Jon Come, David Lauffer, Alex Aronov, Hayley Binch, Dean Boyall, Jean-Damien Charrier, Simon Everitt, Damien Fraysse, Michael Mortimore, Francoise Pierard, Daniel Robinson, Jian Wang, Joanne Pinder, Tiansheng Wang, Albert Pierce
  • Thiazoles and pyrazoles useful as kinase inhibitors
    Patent number: 8268811
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: September 18, 2012
    Assignee: Vertex Pharmaceuticals Inc.
    Inventors: Michael Mortimore, Julian Golec, Christopher Davis, Daniel Robinson, John Studley
  • Thiazoles, imidazoles, and pyrazoles useful as inhibitors of protein kinases
    Patent number: 8236832
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds, to methods of using the compounds and to the compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions.
    Type: Grant
    Filed: August 10, 2009
    Date of Patent: August 7, 2012
    Assignee: Vertex Pharmaceuticals Inc.
    Inventors: Juan-Miguel Jimenez, Ronald Knegtel, Daniel Robinson, Phil Collier
  • CREATING, UPDATING, SAVING, AND PROPAGATING CUSTOMIZED VIEWS OF TABLE AND GRID INFORMATION
    Publication number: 20120159303
    Abstract: Systems, methods, and computer products that create, update, save, and propagate customized views of table and grid information, including spreadsheets. The embodiment of the invention comprises associating at least one column as a first view of the table, associating at least one column as a second view of the table; and combining the first view with the second view, thereby efficiently creating a third view. Further, the combining includes dragging the second view; and dropping the dragged second view into the first view. The combining also includes creating a thumbnail image representing the first view or the second view. It also comprises updating columns that are shared between views. Additionally, the views may be stored, and new views may be propagated from the stored views.
    Type: Application
    Filed: February 24, 2012
    Publication date: June 21, 2012
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Thomas FRIEDRICH, Alexander Daniel ROBINSON, Kathy J. SETZER
  • AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS
    Publication number: 20120142660
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Application
    Filed: December 2, 2011
    Publication date: June 7, 2012
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Hayley Binch, Michael Mortimore, Damien Fraysse, Chris Davis, Michael O'Donnell, Simon Everitt, Daniel Robinson, Joanne Pinder, Andrew Miller
  • Azaindoles useful as inhibitors of JAK and other protein kinases
    Patent number: 8188281
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: May 29, 2012
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Francesco Salituro, Luc Farmer, Randy Bethiel, Edmund Harrington, Jeremy Green, John Court, Jon Come, David Lauffer, Alex Aronov, Hayley Binch, Dean Boyall, Jean-Damien Charrier, Simon Everitt, Damien Fraysse, Michael Mortimore, Francoise Pierard, Daniel Robinson, Jian Wang, Joanne Pinder, Tiansheng Wang, Albert Pierce
  • Aminopyrimidines useful as kinase inhibitors
    Patent number: 8129399
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: March 6, 2012
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Michael Mortimore, Damien Fraysse, Chris Davis, Michael O'Donnell, Simon Everitt, Daniel Robinson, Joanne Pinder, Andrew Miller
  • Benzimidazoles useful as inhibitors of protein kinases
    Patent number: 8076343
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora, FLT-3, or PDK1 protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the invention.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: December 13, 2011
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Hayley Binch, Simon Everitt, Michael Mortimore, Daniel Robinson, Dean Stamos
  • PYRROLOPYRAZINES AND PYRAZOLOPYRAZINES USEFUL AS INHIBITORS OF PROTEIN KINASES
    Publication number: 20110081364
    Abstract: The present invention relates to compounds useful as inhibitors of Aurora protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
    Type: Application
    Filed: July 30, 2010
    Publication date: April 7, 2011
    Inventors: Hayley Binch, Daniel Robinson, Damien Fraysse, Andrew Miller