Patents by Inventor Daniel S. Rivera

Daniel S. Rivera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 11844826
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: December 19, 2023
    Assignee: EpiVax Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • IMMUNOGLOBULIN CHIMERIC MONOMER-DIMER HYBRIDS
    Publication number: 20230023927
    Abstract: The invention relates to a chimeric monomer-dimer hybrid protein wherein the protein comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
    Type: Application
    Filed: June 2, 2022
    Publication date: January 26, 2023
    Inventors: Robert T. PETERS, Adam R. MEZO, Daniel S. RIVERA, Alan J. BITONTI, Susan C. LOW
  • Immunoglobulin chimeric monomer-dimer hybrids
    Patent number: 11401322
    Abstract: The invention relates to a chimeric monomer-dimer hybrid protein wherein the protein comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: August 2, 2022
    Assignee: Bioverativ Therapeutics Inc.
    Inventors: Robert T. Peters, Adam R. Mezo, Daniel S. Rivera, Alan J. Bitonti, Susan C. Low
  • REGULATORY T CELL EPITOPES, COMPOSITIONS AND USES THEREOF
    Publication number: 20220211827
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Application
    Filed: January 14, 2022
    Publication date: July 7, 2022
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • IMMUNOGLOBULIN CHIMERIC MONOMER-DIMER HYBRIDS
    Publication number: 20220010000
    Abstract: The invention relates to a chimeric monomer-dimer hybrid protein wherein the protein comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
    Type: Application
    Filed: September 21, 2021
    Publication date: January 13, 2022
    Inventors: Robert T. PETERS, Adam R. MEZO, Daniel S. RIVERA, Alan J. BITONTI, Susan C. LOW
  • CLOTTING FACTOR-FC CHIMERIC PROTEINS TO TREAT HEMOPHILIA
    Publication number: 20210348150
    Abstract: The invention relates to a chimeric protein comprising at least one clotting factor and at least a portion of an immunoglobulin constant region. The invention relates to a method of treating a hemostatic disorder comprising administering a therapeutically effective amount of a chimeric protein wherein the chimeric protein comprises at least one clotting factor and at least a portion of an immunoglobulin constant region.
    Type: Application
    Filed: April 23, 2021
    Publication date: November 11, 2021
    Inventors: Daniel S. RIVERA, Robert T. PETERS, Alan J. BITONTI
  • Immunoglobulin chimeric monomer-dimer hybrids
    Patent number: 11168125
    Abstract: The invention relates to a chimeric monomer-dimer hybrid protein wherein the protein comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: November 9, 2021
    Assignee: BIOVERATIV THERAPEUTICS INC.
    Inventors: Robert T. Peters, Adam R. Mezo, Daniel S. Rivera, Alan J. Bitonti, Susan C. Low
  • REGULATORY T CELL EPITOPES, COMPOSITIONS AND USES THEREOF
    Publication number: 20210252119
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Application
    Filed: April 21, 2021
    Publication date: August 19, 2021
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Immunoglobulin chimeric monomer-dimer hybrids
    Patent number: 11084866
    Abstract: The invention relates to a chimeric monomer-dimer hybrid protein wherein the protein comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: August 10, 2021
    Assignee: Bioverativ Therapeutics Inc.
    Inventors: Robert T. Peters, Adam R. Mezo, Daniel S. Rivera, Alan J. Bitonti, Susan C. Low
  • REGULATORY T CELL EPITOPES, COMPOSITIONS AND USES THEREOF
    Publication number: 20210236609
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Application
    Filed: April 21, 2021
    Publication date: August 5, 2021
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 11045530
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: June 29, 2021
    Assignee: EpiVax, Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 11045529
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: June 29, 2021
    Assignee: EpiVax, Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 11045528
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: June 29, 2021
    Assignee: EpiVax, Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 11045531
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: June 29, 2021
    Assignee: EpiVax Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 11045532
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: June 29, 2021
    Assignee: EpiVax, Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 10980867
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: April 20, 2021
    Assignee: EpiVax Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 10925940
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 23, 2021
    Assignee: EpiVax, Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 10925941
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: February 23, 2021
    Assignee: EpiVax, Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 10925939
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 23, 2021
    Assignee: EpiVax, Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera
  • Regulatory T cell epitopes, compositions and uses thereof
    Patent number: 10925942
    Abstract: The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: February 23, 2021
    Assignee: EpiVax, Inc.
    Inventors: Anne De Groot, William Martin, Daniel S. Rivera