Abstract: Compression devices for joining tissue and methods for using and fabricating the same.

Abstract: The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.

Abstract: Compression devices for joining tissue and methods for using and fabricating the same.

Abstract: Disclosed herein is a parallel spacer for parallel spacing of a guide wire/pin during surgery. The parallel spacer incudes a parallel spacer body having a top surface and a bottom surface. The parallel spacer also includes a first aperture extending through the body and defined by one or more internal walls that extends to the opening in the top surface. The aperture is sized to receive a first guide and hold the first guide in a first orientation. A second aperture extends between a second opening in the top surface and a second opening in the bottom surface. The second aperture is defined by one or more walls located within the spacer body. The one or more walls connect the second opening in the top surface to the second opening in the bottom surface. The aperture is sized to receive another guide and hold the other guide in a parallel orientation to the first orientation at a first distance from the first aperture.

Abstract: Systems, methods and devices for spinal fusion are disclosed. In particular, certain disclosed embodiments are configured to permit the addition of lordosis to a spinal fusion cage after implantation through the use of various expansion mechanisms to spread arms of the spinal fusion cage. Disclosed embodiments may include the use of a threaded wedge to expand the arms, the use of a keel within a series of detents, the use of supplemental fixation screws, and the use of a rotating cam.

Abstract: Systems, methods and devices for spinal fusion are disclosed. In particular, certain disclosed embodiments are configured to permit the addition of lordosis to a spinal fusion cage after implantation through the use of various expansion mechanisms to spread arms of the spinal fusion cage. Disclosed embodiments may include the use of a threaded wedge to expand the arms, the use of a keel within a series of detents, the use of supplemental fixation screws, and the use of a rotating cam.

Abstract: Compression devices for joining tissue and methods for using and fabricating the same.

Abstract: Compression devices for joining tissue and methods for using and fabricating the same.

Abstract: Compression devices for joining tissue and methods for using and fabricating the same.

Abstract: Compression devices for joining tissue and methods for using and fabricating the same.

Abstract: A device for placement between two adjacent spinous processes of a spinal column to treat a spinal condition, and a method for performing a procedure on a spine of a patient, are provided. The device may include a first member, a second member mounted onto the first member, and a locking plug configured to restrict movement of the second member relative to the first member. The method may include positioning a portion of a first member between two adjacent spinous processes of the spine, advancing a second member along a length of the first member, and restricting the second member from moving relative to the first member.

Abstract: Disclosed herein is a parallel spacer for parallel spacing of a guide wire/pin during surgery. The parallel spacer incudes a parallel spacer body having a top surface and a bottom surface. The parallel spacer also includes a first aperture extending through the body and defined by one or more internal walls that extends to the opening in the top surface. The aperture is sized to receive a first guide and hold the first guide in a first orientation. A second aperture extends between a second opening in the top surface and a second opening in the bottom surface. The second aperture is defined by one or more walls located within the spacer body. The one or more walls connect the second opening in the top surface to the second opening in the bottom surface. The aperture is sized to receive another guide and hold the other guide in a parallel orientation to the first orientation at a first distance from the first aperture.

Abstract: Disclosed herein is a surgical press for setting a surgical device into bone. The surgical press system includes an elongated shaft having a distal portion and a proximal portion. The shaft is configured for insertion into a guide. The surgical press system includes threads extending along an axial portion of the distal end of the shaft. The threads are configured to pull the shaft into bone as the shaft rotates. The surgical press system includes a press element associated with a proximal portion of the shaft such that as the shaft is rotated, the threads pull the shaft into the bone causing the press element to press the surgical device into the bone. The surgical press system includes a collection region located in the distal portion of the shaft and configured to receive bone material removed from the bone due to advancement of the shaft.

Abstract: Disclosed herein is a bone cage that includes a shaft extending from a head to a tapered tip and including threads disposed on an external surface of the shaft. The cage also includes a plurality of fenestrations defining a row disposed in at least a first helix along at least a portion of the shaft, each of the plurality of fenestrations extend directly through a natural portion of the thread. The cage also includes a cannula positioned within the shaft and extending from an opening in the head to another opening in the tip. Each of the fenestrations are defined by a wall that extends from the exterior of the shaft to the cannula.

Abstract: Disclosed herein is a parallel spacer for parallel spacing of a guide wire/pin during surgery. The parallel spacer includes a parallel spacer body having a top surface and a bottom surface. The parallel spacer also includes a first aperture extending through the body and defined by one or more internal walls that extends to the opening in the top surface. The aperture is sized to receive a first guide and hold the first guide in a first orientation. A second aperture extends between a second opening in the top surface and a second opening in the bottom surface. The second aperture is defined by one or more walls located within the spacer body. The one or more walls connect the second opening in the top surface to the second opening in the bottom surface. The aperture is sized to receive another guide and hold the other guide in a parallel orientation to the first orientation at a first distance from the first aperture.