Patents by Inventor Daniel Saltzman
Daniel Saltzman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240091275Abstract: A method of treating cancer includes administering a dose of a chemotherapy agent in combination with a dose of a composition consisting essentially of attenuated Salmonella typhimurium. The dose of the chemotherapy agent is lower than a maximum effective dose of the chemotherapy agent. The combination provides a synergistic reduction in tumor burden when compared to the reduction in tumor burden provided by administration of an equivalent dose of the chemotherapy agent without the composition consisting essentially of attenuated Salmonella typhimurium.Type: ApplicationFiled: January 26, 2023Publication date: March 21, 2024Inventor: Daniel A. SALTZMAN
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Publication number: 20230057396Abstract: The present disclosure provides a method of treating a solid tumor cancer. The method includes administering a combination to a subject in need thereof. The combination includes at least two chemotherapy agents and a dose of a composition consisting essentially of attenuated Salmonella typhimurium. The present disclosure also provides an anti-tumor agent for use in a method of treating cancer. In such instances, the anti-tumor agent may include the combination.Type: ApplicationFiled: December 26, 2020Publication date: February 23, 2023Inventors: Aydin S. MORADIAN, Daniel A. SALTZMAN
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Patent number: 11576936Abstract: A method of treating cancer includes administering a dose of a chemotherapy agent in combination with a dose of a composition consisting essentially of attenuated Salmonella typhimurium. The dose of the chemotherapy agent is lower than a maximum effective dose of the chemotherapy agent. The combination provides a synergistic reduction in tumor burden when compared to the reduction in tumor burden provided by administration of an equivalent dose of the chemotherapy agent without the composition consisting essentially of attenuated Salmonella typhimurium.Type: GrantFiled: December 6, 2017Date of Patent: February 14, 2023Assignee: Salspera, LLCInventor: Daniel A. Saltzman
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Publication number: 20200085883Abstract: A method of treating cancer includes administering a dose of a chemotherapy agent in combination with a dose of a composition consisting essentially of attenuated Salmonella typhimurium. The dose of the chemotherapy agent is lower than a maximum effective dose of the chemotherapy agent. The combination provides a synergistic reduction in tumor burden when compared to the reduction in tumor burden provided by administration of an equivalent dose of the chemotherapy agent without the composition consisting essentially of attenuated Salmonella typhimurium.Type: ApplicationFiled: December 6, 2017Publication date: March 19, 2020Inventor: Daniel A. SALTZMAN
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Patent number: 9623278Abstract: An exercise mat including a material sized and shaped to support at least one user body part thereon, the material having an upper planar surface, a single starting point representing a number zero on the upper planar surface, and at least two series of sequential integers disposed on the upper planar surface and extending from the single starting point. Each of the at least two series of sequential integers corresponding to a coordinate and placement site for a body part of a user to facilitate measurement of a linear distance along the upper planar surface.Type: GrantFiled: January 26, 2016Date of Patent: April 18, 2017Inventor: Daniel Saltzman
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Publication number: 20160136476Abstract: An exercise mat including a material sized and shaped to support at least one user body part thereon, the material having an upper planar surface, a single starting point representing a number zero on the upper planar surface, and at least two series of sequential integers disposed on the upper planar surface and extending from the single starting point.Type: ApplicationFiled: January 26, 2016Publication date: May 19, 2016Inventor: Daniel Saltzman
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Patent number: 8647618Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.Type: GrantFiled: June 15, 2012Date of Patent: February 11, 2014Assignee: Cureium Therapeutics LLCInventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
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Patent number: 8449925Abstract: A method of lowering diastolic blood pressure and LDL cholesterol in a human subject. The method consists of the steps of: (a) administering to the human subject a mixture of cold-pressed botanic seed oils; (b) administering to the human subject the mixture of cold-pressed botanic seed oils and a mixture of botanic seed flours; and (c) lowering the human subject's diastolic blood pressure and LDL cholesterol. A method of measurement of the synergistic effect of cold-pressed botanic seed oils and botanic seed flours in lowering diastolic blood pressure and LDL cholesterol in a human subject. The method consists of the steps of: a) administering to the human subject a mixture of cold-pressed botanic seed oils; b) administering to the human subject a mixture of botanic seed flours; and c) measuring the human subject's diastolic blood pressure and LDL cholesterol. A composition of matter exhibiting diastolic blood pressure lowering activity and LDL cholesterol lowering activity in a human subject.Type: GrantFiled: July 2, 2008Date of Patent: May 28, 2013Assignee: Botanic Oil Innovations, Inc.Inventors: Arnold Leonard, Daniel Saltzman, Mark J. Mueller
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Publication number: 20130045525Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.Type: ApplicationFiled: June 15, 2012Publication date: February 21, 2013Applicant: BOTANIC OIL INNOVATIONS, INC.Inventors: ARNOLD S. LEONARD, DANIEL A. SALTZMAN, MARK J. MUELLER
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Patent number: 8221739Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.Type: GrantFiled: April 17, 2009Date of Patent: July 17, 2012Assignee: Botanic Oil Innovations, Inc.Inventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
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Patent number: 7897194Abstract: A composition of cold pressed botanic oils exhibiting antioxidant activity. The composition is a combination of at least two oils, which can be black cumin oil, black raspberry oil, red raspberry oil, pomegranate oil, pumpkin oil, or sesame, flax, chardonnay grape seed oil or any other fruit, herb, vegetable, grain or nut oil. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils. A method of producing a composition of botanic oils exhibiting antioxidant activity, comprising extracting oil in an oxygen deprived environment from fruits and vegetables and combining the extracted oils. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils.Type: GrantFiled: April 18, 2007Date of Patent: March 1, 2011Assignee: Botanic Oil Innovations, Inc.Inventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
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Publication number: 20100098665Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.Type: ApplicationFiled: April 17, 2009Publication date: April 22, 2010Applicant: BOTANIC OIL INNOVATIONS, INC.Inventors: ARNOLD S. LEONARD, DANIEL A. SALTZMAN, MARK J. MUELLER
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Publication number: 20090324759Abstract: A method of treating a subject requiring immune mediation includes administering to the subject an immunostimulatory composition which contains black raspberry seed oil. Administering this composition stimulates the production of certain immune cells, including NK cells and CD8(+) lymphocytes. Administering the composition by this method also provides a method of treating, preventing, or ameliorating a condition or disease in the subject requiring enhanced immune system support.Type: ApplicationFiled: June 22, 2009Publication date: December 31, 2009Applicant: Botanic Oil Innovations, Inc.Inventors: Daniel A. Saltzman, Arnold S. Leonard, Mark J. Mueller
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Publication number: 20080260645Abstract: A method of lowering diastolic blood pressure and LDL cholesterol in a human subject. The method consists of the steps of: (a) administering to the human subject a mixture of cold-pressed botanic seed oils; (b) administering to the human subject the mixture of cold-pressed botanic seed oils and a mixture of botanic seed flours; and (c) lowering the human subject's diastolic blood pressure and LDL cholesterol. A method of measurement of the synergistic effect of cold-pressed botanic seed oils and botanic seed flours in lowering diastolic blood pressure and LDL cholesterol in a human subject. The method consists of the steps of: a) administering to the human subject a mixture of cold-pressed botanic seed oils; b) administering to the human subject a mixture of botanic seed flours; and c) measuring the human subject's diastolic blood pressure and LDL cholesterol. A composition of matter exhibiting diastolic blood pressure lowering activity and LDL cholesterol lowering activity in a human subject.Type: ApplicationFiled: July 2, 2008Publication date: October 23, 2008Applicant: Botanic Oil Innovations, Inc.Inventors: Arnold Leonard, Daniel Saltzman, Mark Mueller
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Publication number: 20070243310Abstract: A composition of cold pressed botanic oils exhibiting antioxidant activity. The composition is a combination of at least two oils, which can be black cumin oil, black raspberry oil, red raspberry oil, pomegranate oil, pumpkin oil, or sesame, flax, chardonnay grape seed oil or any other fruit, herb, vegetable, grain or nut oil. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils. A method of producing a composition of botanic oils exhibiting antioxidant activity, comprising extracting oil in an oxygen deprived environment from fruits and vegetables and combining the extracted oils. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils.Type: ApplicationFiled: April 18, 2007Publication date: October 18, 2007Applicant: Botanic Oil Innovations, Inc.Inventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
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Publication number: 20070128301Abstract: A composition useful as an immunostimulant and as an adjuvant to support various cancer treatment modalities is disclosed. Additionally, the use of a composition comprising seed oils and/or flours derived from the seeds and/or mixtures thereof as immunostimulants and as a daily supplements to enhance the immune system activity of subjects is also disclosed.Type: ApplicationFiled: September 7, 2005Publication date: June 7, 2007Inventors: Daniel Saltzman, Arnold Leonard, Mark Mueller
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Publication number: 20050244375Abstract: The invention discloses a method for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding human interleukin-2 and an oil containing a high antioxidant concentration and a method for administering the composition.Type: ApplicationFiled: April 29, 2004Publication date: November 3, 2005Inventors: Arnold Leonard, Daniel Saltzman, Mark Mueller