Patents by Inventor Daniel Saltzman

Daniel Saltzman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240091275
    Abstract: A method of treating cancer includes administering a dose of a chemotherapy agent in combination with a dose of a composition consisting essentially of attenuated Salmonella typhimurium. The dose of the chemotherapy agent is lower than a maximum effective dose of the chemotherapy agent. The combination provides a synergistic reduction in tumor burden when compared to the reduction in tumor burden provided by administration of an equivalent dose of the chemotherapy agent without the composition consisting essentially of attenuated Salmonella typhimurium.
    Type: Application
    Filed: January 26, 2023
    Publication date: March 21, 2024
    Inventor: Daniel A. SALTZMAN
  • Publication number: 20230057396
    Abstract: The present disclosure provides a method of treating a solid tumor cancer. The method includes administering a combination to a subject in need thereof. The combination includes at least two chemotherapy agents and a dose of a composition consisting essentially of attenuated Salmonella typhimurium. The present disclosure also provides an anti-tumor agent for use in a method of treating cancer. In such instances, the anti-tumor agent may include the combination.
    Type: Application
    Filed: December 26, 2020
    Publication date: February 23, 2023
    Inventors: Aydin S. MORADIAN, Daniel A. SALTZMAN
  • Patent number: 11576936
    Abstract: A method of treating cancer includes administering a dose of a chemotherapy agent in combination with a dose of a composition consisting essentially of attenuated Salmonella typhimurium. The dose of the chemotherapy agent is lower than a maximum effective dose of the chemotherapy agent. The combination provides a synergistic reduction in tumor burden when compared to the reduction in tumor burden provided by administration of an equivalent dose of the chemotherapy agent without the composition consisting essentially of attenuated Salmonella typhimurium.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: February 14, 2023
    Assignee: Salspera, LLC
    Inventor: Daniel A. Saltzman
  • Publication number: 20200085883
    Abstract: A method of treating cancer includes administering a dose of a chemotherapy agent in combination with a dose of a composition consisting essentially of attenuated Salmonella typhimurium. The dose of the chemotherapy agent is lower than a maximum effective dose of the chemotherapy agent. The combination provides a synergistic reduction in tumor burden when compared to the reduction in tumor burden provided by administration of an equivalent dose of the chemotherapy agent without the composition consisting essentially of attenuated Salmonella typhimurium.
    Type: Application
    Filed: December 6, 2017
    Publication date: March 19, 2020
    Inventor: Daniel A. SALTZMAN
  • Patent number: 9623278
    Abstract: An exercise mat including a material sized and shaped to support at least one user body part thereon, the material having an upper planar surface, a single starting point representing a number zero on the upper planar surface, and at least two series of sequential integers disposed on the upper planar surface and extending from the single starting point. Each of the at least two series of sequential integers corresponding to a coordinate and placement site for a body part of a user to facilitate measurement of a linear distance along the upper planar surface.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: April 18, 2017
    Inventor: Daniel Saltzman
  • Publication number: 20160136476
    Abstract: An exercise mat including a material sized and shaped to support at least one user body part thereon, the material having an upper planar surface, a single starting point representing a number zero on the upper planar surface, and at least two series of sequential integers disposed on the upper planar surface and extending from the single starting point.
    Type: Application
    Filed: January 26, 2016
    Publication date: May 19, 2016
    Inventor: Daniel Saltzman
  • Patent number: 8647618
    Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: February 11, 2014
    Assignee: Cureium Therapeutics LLC
    Inventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
  • Patent number: 8449925
    Abstract: A method of lowering diastolic blood pressure and LDL cholesterol in a human subject. The method consists of the steps of: (a) administering to the human subject a mixture of cold-pressed botanic seed oils; (b) administering to the human subject the mixture of cold-pressed botanic seed oils and a mixture of botanic seed flours; and (c) lowering the human subject's diastolic blood pressure and LDL cholesterol. A method of measurement of the synergistic effect of cold-pressed botanic seed oils and botanic seed flours in lowering diastolic blood pressure and LDL cholesterol in a human subject. The method consists of the steps of: a) administering to the human subject a mixture of cold-pressed botanic seed oils; b) administering to the human subject a mixture of botanic seed flours; and c) measuring the human subject's diastolic blood pressure and LDL cholesterol. A composition of matter exhibiting diastolic blood pressure lowering activity and LDL cholesterol lowering activity in a human subject.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: May 28, 2013
    Assignee: Botanic Oil Innovations, Inc.
    Inventors: Arnold Leonard, Daniel Saltzman, Mark J. Mueller
  • Publication number: 20130045525
    Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.
    Type: Application
    Filed: June 15, 2012
    Publication date: February 21, 2013
    Applicant: BOTANIC OIL INNOVATIONS, INC.
    Inventors: ARNOLD S. LEONARD, DANIEL A. SALTZMAN, MARK J. MUELLER
  • Patent number: 8221739
    Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.
    Type: Grant
    Filed: April 17, 2009
    Date of Patent: July 17, 2012
    Assignee: Botanic Oil Innovations, Inc.
    Inventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
  • Patent number: 7897194
    Abstract: A composition of cold pressed botanic oils exhibiting antioxidant activity. The composition is a combination of at least two oils, which can be black cumin oil, black raspberry oil, red raspberry oil, pomegranate oil, pumpkin oil, or sesame, flax, chardonnay grape seed oil or any other fruit, herb, vegetable, grain or nut oil. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils. A method of producing a composition of botanic oils exhibiting antioxidant activity, comprising extracting oil in an oxygen deprived environment from fruits and vegetables and combining the extracted oils. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils.
    Type: Grant
    Filed: April 18, 2007
    Date of Patent: March 1, 2011
    Assignee: Botanic Oil Innovations, Inc.
    Inventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
  • Publication number: 20100098665
    Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.
    Type: Application
    Filed: April 17, 2009
    Publication date: April 22, 2010
    Applicant: BOTANIC OIL INNOVATIONS, INC.
    Inventors: ARNOLD S. LEONARD, DANIEL A. SALTZMAN, MARK J. MUELLER
  • Publication number: 20090324759
    Abstract: A method of treating a subject requiring immune mediation includes administering to the subject an immunostimulatory composition which contains black raspberry seed oil. Administering this composition stimulates the production of certain immune cells, including NK cells and CD8(+) lymphocytes. Administering the composition by this method also provides a method of treating, preventing, or ameliorating a condition or disease in the subject requiring enhanced immune system support.
    Type: Application
    Filed: June 22, 2009
    Publication date: December 31, 2009
    Applicant: Botanic Oil Innovations, Inc.
    Inventors: Daniel A. Saltzman, Arnold S. Leonard, Mark J. Mueller
  • Publication number: 20080260645
    Abstract: A method of lowering diastolic blood pressure and LDL cholesterol in a human subject. The method consists of the steps of: (a) administering to the human subject a mixture of cold-pressed botanic seed oils; (b) administering to the human subject the mixture of cold-pressed botanic seed oils and a mixture of botanic seed flours; and (c) lowering the human subject's diastolic blood pressure and LDL cholesterol. A method of measurement of the synergistic effect of cold-pressed botanic seed oils and botanic seed flours in lowering diastolic blood pressure and LDL cholesterol in a human subject. The method consists of the steps of: a) administering to the human subject a mixture of cold-pressed botanic seed oils; b) administering to the human subject a mixture of botanic seed flours; and c) measuring the human subject's diastolic blood pressure and LDL cholesterol. A composition of matter exhibiting diastolic blood pressure lowering activity and LDL cholesterol lowering activity in a human subject.
    Type: Application
    Filed: July 2, 2008
    Publication date: October 23, 2008
    Applicant: Botanic Oil Innovations, Inc.
    Inventors: Arnold Leonard, Daniel Saltzman, Mark Mueller
  • Publication number: 20070243310
    Abstract: A composition of cold pressed botanic oils exhibiting antioxidant activity. The composition is a combination of at least two oils, which can be black cumin oil, black raspberry oil, red raspberry oil, pomegranate oil, pumpkin oil, or sesame, flax, chardonnay grape seed oil or any other fruit, herb, vegetable, grain or nut oil. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils. A method of producing a composition of botanic oils exhibiting antioxidant activity, comprising extracting oil in an oxygen deprived environment from fruits and vegetables and combining the extracted oils. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils.
    Type: Application
    Filed: April 18, 2007
    Publication date: October 18, 2007
    Applicant: Botanic Oil Innovations, Inc.
    Inventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
  • Publication number: 20070128301
    Abstract: A composition useful as an immunostimulant and as an adjuvant to support various cancer treatment modalities is disclosed. Additionally, the use of a composition comprising seed oils and/or flours derived from the seeds and/or mixtures thereof as immunostimulants and as a daily supplements to enhance the immune system activity of subjects is also disclosed.
    Type: Application
    Filed: September 7, 2005
    Publication date: June 7, 2007
    Inventors: Daniel Saltzman, Arnold Leonard, Mark Mueller
  • Publication number: 20050244375
    Abstract: The invention discloses a method for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding human interleukin-2 and an oil containing a high antioxidant concentration and a method for administering the composition.
    Type: Application
    Filed: April 29, 2004
    Publication date: November 3, 2005
    Inventors: Arnold Leonard, Daniel Saltzman, Mark Mueller