Abstract: Surgical stapling devices have a surgical buttress attached to an anvil jaw member, a cartridge jaw member, or both. The surgical buttress possesses a therapeutic layer of a therapeutic agent in a pattern thereon. The pattern may reflect various concentrations of a therapeutic agent, different therapeutic agents, or both.

Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.

Abstract: A surgical stapling apparatus includes a staple cartridge assembly, an anvil assembly operatively associated with the staple cartridge assembly, and a surgical buttress releasably coupled to the staple cartridge assembly or the anvil assembly. The staple cartridge assembly includes a tissue facing surface having staple retaining slots defined therein, each staple retaining slot housing a staple therein, and a circular knife disposed radially inwardly of the tissue facing surface. The anvil assembly includes an anvil member including a tissue facing surface and an anvil shaft extending from the anvil member. The surgical buttress has a circular configuration defining a central aperture therethrough. The surgical buttress includes an inner concentric portion having a therapeutic coating disposed thereon and an outer concentric portion free of the therapeutic coating.

Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.

Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.

Abstract: A surgical stapling apparatus includes a staple cartridge assembly, an anvil assembly operatively associated with the staple cartridge assembly, and a surgical buttress releasably coupled to the staple cartridge assembly or the anvil assembly. The staple cartridge assembly includes a tissue facing surface having staple retaining slots defined therein, each staple retaining slot housing a staple therein, and a circular knife disposed radially inwardly of the tissue facing surface. The anvil assembly includes an anvil member including a tissue facing surface and an anvil shaft extending from the anvil member. The surgical buttress has a circular configuration defining a central aperture therethrough. The surgical buttress includes an inner concentric portion having a therapeutic coating disposed thereon and an outer concentric portion free of the therapeutic coating.

Abstract: Surgical stapling devices have a surgical buttress attached to an anvil jaw member, a cartridge jaw member, or both. The surgical buttress possesses a therapeutic layer of a therapeutic agent in a pattern thereon. The pattern may reflect various concentrations of a therapeutic agent, different therapeutic agents, or both.

Abstract: Surgical stapling devices have a first buttress attached to an anvil jaw member and a second buttress attached to a cartridge jaw member. In use, the first buttress and the second buttress sandwich tissue being stapled by the surgical stapling device.

Abstract: A surgical stapling apparatus includes a staple cartridge assembly, an anvil assembly operatively associated with the staple cartridge assembly, and a surgical buttress releasably coupled to the staple cartridge assembly or the anvil assembly. The staple cartridge assembly includes a tissue facing surface having staple retaining slots defined therein, each staple retaining slot housing a staple therein, and a circular knife disposed radially inwardly of the tissue facing surface. The anvil assembly includes an anvil member including a tissue facing surface and an anvil shaft extending from the anvil member. The surgical buttress has a circular configuration defining a central aperture therethrough. The surgical buttress includes an inner concentric portion having a therapeutic coating disposed thereon and an outer concentric portion free of the therapeutic coating.

Abstract: A surgical stapling apparatus includes a staple cartridge assembly, an anvil assembly operatively associated with the staple cartridge assembly, and a surgical buttress releasably coupled to the staple cartridge assembly or the anvil assembly. The staple cartridge assembly includes a tissue facing surface having staple retaining slots defined therein, each staple retaining slot housing a staple therein, and a circular knife disposed radially inwardly of the tissue facing surface. The anvil assembly includes an anvil member including a tissue facing surface and an anvil shaft extending from the anvil member. The surgical buttress has a circular configuration defining a central aperture therethrough. The surgical buttress includes an inner concentric portion having a therapeutic coating disposed thereon and an outer concentric portion free of the therapeutic coating.

Abstract: Techniques for improving implementation of a downhole tool string to be deployed in a borehole formed in a sub-surface formation. In some embodiments, a design device determines a model that describes expected relationship between properties of the downhole tool string, the borehole, the sub-surface formation, and mud cake expected to be formed in the borehole; determines calibration locations along the borehole based on properties of the borehole; determines candidate spacer configurations based on contact force expected to occur at contact points between the downhole tool string and the mud cake when deployed with each of the candidate spacer configuration via the model; and determines a final spacer configuration to be used to attach one or more spacers along the downhole tool string based on expected head tension to move the downhole tool string when deployed in the borehole with each of the candidate spacer configurations via the model.

Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including an elongate rectangular body having a proximal portion, a distal portion, and opposing lateral sides running along the elongate rectangular body from the proximal portion to the distal portion. The substrate possesses a therapeutic layer of a therapeutic agent along at least one of its lateral sides. Methods and systems for producing such devices are also provided.

Abstract: A manufacturing system that manufactures a downhole tool string, which includes a model that describes relationship between properties of the downhole tool string, properties of a borehole, properties of a formation, and properties of a mud cake formed on a surface of the borehole and a design device that iteratively determines contact parameters that describe one or more contact points expected between the downhole tool string and the mud cake based at least in part on the model, in which the contact parameters comprise contact force expected at each of the contact points, adjusts the properties of the downhole tool string to add a spacer at one of the contact points associated with highest contact force, and indicates location, type, or both of the spacer to enable the manufacturing system to attach the spacer to the downhole tool string before deployment of the downhole tool string in the borehole.

Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.

Abstract: Techniques for improving implementation of a downhole tool string to be deployed in a borehole formed in a sub-surface formation. In some embodiments, a design device determines a model that describes expected relationship between properties of the downhole tool string, the borehole, the sub-surface formation, and mud cake expected to be formed in the borehole; determines calibration locations along the borehole based on properties of the borehole; determines candidate spacer configurations based on contact force expected to occur at contact points between the downhole tool string and the mud cake when deployed with each of the candidate spacer configuration via the model; and determines a final spacer configuration to be used to attach one or more spacers along the downhole tool string based on expected head tension to move the downhole tool string when deployed in the borehole with each of the candidate spacer configurations via the model.

Abstract: A number of fan assemblies are shown. Configurations are shown that include one or more diffusers. Diffuser locations and specific diffuser configurations are described that improve one or more fan assembly characteristics, including, but not limited to fan efficiency.

Abstract: Apparatus and methods for aggregating work activity information, application usage and/or self-reported work status designations are presented. Tracked activity information can be used to automatically determine worker status, or audit status designations manually submitted by workers. Reporting can be delivered to users (a) tracking activities and progress against predetermined objectives, and/or (b) comparing worker activities and progress against that of other workers. Worker activity information can be used by managers to evaluate and improve worker performance.

Abstract: The present invention provides a leveling control system for a forestry machine (10) employing position sensors that relay information about the orientation of the carriage (12) in relation to the swing-house assembly (14) in order to control roll and pitch in a manner that maximizes the operating envelop of the leveling mechanism (38). The angles of pitch and roll of the swing-house assembly (14) in relation to the carriage (12) are measured and/or calculated and a controller (24) limits operation of the leveling mechanism (38) to an operating envelop that may be described in terms of pitch and droll. The cylinders (54, 56) are decelerated gradually as the operating envelop is approached. The controller (24) can include an automatic leveling mode. The controller (24) can change the function of the fore, aft, left and right operator controls so that they are true from the operator's frame of reference regardless of the rotary position of the cab relative to the carriage (12).

Abstract: The present invention provides a leveling control system for a forestry machine (10) employing position sensors that relay information about the orientation of the carriage (12) in relation to the swing-house assembly (14) in order to control roll and pitch in a manner that maximizes the operating envelop of the leveling mechanism (38). The angles of pitch and roll of the swing-house assembly (14) in relation to the carriage (12) are measured and/or calculated and a controller (24) limits operation of the leveling mechanism (38) to an operating envelop that may be described in terms of pitch and droll. The cylinders (54, 56) are decelerated gradually as the operating envelop is approached. The controller (24) can include an automatic leveling mode. The controller (24) can change the function of the fore, aft, left and right operator controls so that they are true from the operator's frame of reference regardless of the rotary position of the cab relative to the carriage (12).