Abstract: A motorized valve includes a body with at least one intake duct and one outlet duct, a plugging member movably mounted in the body to plug or release a passage between the intake duct and the outlet duct, and a motorized control system for controlling the movement of the plugging member. The motorized control system also includes a plug valve connecting intake and outlet ducts, a gear motor including an electric motor and a reduction gear train. The gear train includes an exit wheel rotating the plug of the valve so as to allow progressive opening of the valve, and the gear motor is formed by a casing including the electric motor and reduction gear train, the valve body being integrally formed with the casing.

Abstract: A positioning actuator includes a stator assembly and a rotor, a printed circuit provided with electronic components, as well as a reduction gear for driving a rotary member. It includes two complementary blocks, the first block being made up of a shell having thermal conductivity no lower than 1 W/m/K, the first block including the reduction gear and having a passage for the output shaft of the reducing gear as well as an open opposing surface; the second block being formed by overmoulding the stator assembly and having a rear bearing recess for the rotor, the second block having a joining surface which complements a joining surface of the first block. The actuator also includes the electronic circuit which is positioned in a space defined between the first and second blocks. The disclosure also relates to a method for manufacturing such an actuator.

Abstract: An electrically controlled valve for the circulation of hot fluids is made up of an electromagnetic actuator and a valve. The valve has an opening provided with a movable sealing member driven by a rotation shaft perpendicular to the axis of the opening, the electromagnetic actuator driving the rotation of the shaft, the output shaft of the actuator being substantially coaxial with the rotation shaft. The front end of the rotation shaft and the front end of the output shaft are not in direct contact. The coupling between the rotation shaft of the valve and the output shaft of the actuator is provided by a coupling member placed between the front end of the output shaft and the front end of the shaft. The coupling member transmitting rotation torque with a misalignment tolerance between the output shaft and the rotation shaft of the valve. The valve also having thermally insulation for mechanical connection between peripheral areas of the body of the actuator and the body of the valve.

Abstract: A motorized valve includes a body with at least one intake duct and one outlet duct, a plugging member movably mounted in the body to plug or release a passage between the intake duct and the outlet duct, and a motorized control system for controlling the movement of the plugging member. The motorized control system also includes a plug valve connecting intake and outlet ducts, a gear motor including an electric motor and a reduction gear train. The gear train includes an exit wheel rotating the plug of the valve so as to allow progressive opening of the valve, and the gear motor is formed by a casing including the electric motor and reduction gear train, the valve body being integrally formed with the casing.

Abstract: An electrically controlled valve for the circulation of hot fluids is made up of an electromagnetic actuator and a valve. The valve has an opening provided with a movable sealing member driven by a rotation shaft perpendicular to the axis of the opening, the electromagnetic actuator driving the rotation of the shaft, the output shaft of the actuator being substantially coaxial with the rotation shaft. The front end of the rotation shaft and the front end of the output shaft are not in direct contact. The coupling between the rotation shaft of the valve and the output shaft of the actuator is provided by a coupling member placed between the front end of the output shaft and the front end of the shaft. The coupling member transmitting rotation torque with a misalignment tolerance between the output shaft and the rotation shaft of the valve. The valve also having thermally insulation for mechanical connection between peripheral areas of the body of the actuator and the body of the valve.

Abstract: A positioning actuator includes a stator assembly and a rotor, a printed circuit provided with electronic components, as well as a reduction gear for driving a rotary member. It includes two complementary blocks, the first block being made up of a shell having thermal conductivity no lower than 1 W/m/K, the first block including the reduction gear and having a passage for the output shaft of the reducing gear as well as an open opposing surface; the second block being formed by overmoulding the stator assembly and having a rear bearing recess for the rotor, the second block having a joining surface which complements a joining surface of the first block. The actuator also includes the electronic circuit which is positioned in a space defined between the first and second blocks. The disclosure also relates to a method for manufacturing such an actuator.

Abstract: A delivery system for delivering a therapeutic agent to a patient includes a catheter, a stop feature, a container and a bar. The catheter has a proximal end and a distal end and includes a body defining a lumen that extends to the distal end of the catheter. The stop feature is in proximity to the distal end of the catheter. The container is configured to house the therapeutic agent and is insertable and slidably disposable in the lumen of the catheter. The container is also configured to engage the stop feature of the catheter. The bar is slidably disposable in the lumen of the catheter. Sliding of the bar distally in the lumen forces the therapeutic agent out of the container and out of the lumen when the container is engaged with the stop feature. The stop feature is configured to inhibit the container from exiting the lumen.

Abstract: The subject invention is directed to methods of treating cardiac pacing dysfunction by administering HCN genes, alone or in combination with other genes.

Abstract: A delivery system for delivering a therapeutic agent to a patient includes a catheter, a stop feature, a container and a bar. The catheter has a proximal end and a distal end and includes a body defining a lumen that extends to the distal end of the catheter. The stop feature is in proximity to the distal end of the catheter. The container is configured to house the therapeutic agent and is insertable and slidably disposable in the lumen of the catheter. The container is also configured to engage the stop feature of the catheter. The bar is slidably disposable in the lumen of the catheter. Sliding of the bar distally in the lumen forces the therapeutic agent out of the container and out of the lumen when the container is engaged with the stop feature. The stop feature is configured to inhibit the container from exiting the lumen.

Abstract: The invention relates to an electrical connector assembly for a brushless electromagnetic motor, comprising a 3-phase electrical stator winding and X windings per phase, connected in series or in parallel, characterized in comprising a circular wire guide with slots designed to hold the ends of the wires of the windings and a connector support comprising at least three circular connector tracks, three of said tracks being each terminated with a thimble and which are axially extended by wire grips to ensure the electrical contact for the 3 phases of the motor through the slots of the wire guides and wherein the thimbles exit the motor via a connector.

Abstract: A delivery system for delivering a therapeutic agent to a patient includes a catheter, a stop feature, a container and a bar. The catheter has a proximal end and a distal end and includes a body defining a lumen that extends to the distal end of the catheter. The stop feature is in proximity to the distal end of the catheter. The container is configured to house the therapeutic agent and is insertable and slidably disposable in the lumen of the catheter. The container is also configured to engage the stop feature of the catheter. The bar is slidably disposable in the lumen of the catheter. Sliding of the bar distally in the lumen forces the therapeutic agent out of the container and out of the lumen when the container is engaged with the stop feature. The stop feature is configured to inhibit the container from exiting the lumen.

Abstract: The subject invention is directed to methods of treating cardiac pacing dysfunction by administering HCN genes, alone or in combination with other genes.

Abstract: The present invention includes systems, devices, and methods relating to the monitoring of the functional maturation of biological interventions effecting cardiac pacing; the systems, devices, and methods including an implantable electronic pulse generator delivering artificial cardiac pacing; a means for halting the electronic pulse generator delivering artificial cardiac pacing at predetermined data collection intervals; and a sensor for recording and storing data on one or more intrinsic physiological parameters of cardiac pacing during the predetermined data collection intervals.

Abstract: A dashboard indicator module including a rotating actuator including a hollow output shaft controlling movement of an indicator with a light conducting path, connected to a light source, diffusing a light at an angle, and a reduction gear set. The external diameter of the conducting path is between 2.6 and 5.5 millimeters.

Abstract: The present invention includes systems, devices, and methods relating to the monitoring of the functional maturation of biological interventions effecting cardiac pacing.

Abstract: The present invention provides for topical adhesive patch that includes a backing having a front side and a back side; a formulation in contact with the front side of the backing, the formulation including an adhesive; and at least one antimicrobial. The antimicrobial is integrally bonded to the back side of the backing. The present invention also provides for a method of reducing the number of microbes located upon a topical skin surface of a mammal, as well as a method of preventing the transmission of a communicable disease capable of being transmitted by physical contact. The methods include topically contacting a skin surface of the mammal with the back side of the topical adhesive patch.

Abstract: A method of connecting an electric actuator to a printed circuit by metal contacts having an open contact zone. The metal contacts are soldered to the printed circuit using an SMD-type automated method performed at a high speed and at a high temperature, and the electrical connection pins of the actuator can be mechanically connected to the metal contacts without soldering by butting the contact zone of the metal contacts against the connection pins of the actuator once the connection pins have been inserted through the contact zone.

Abstract: The invention relates to an electrical connector assembly for a brushless electromagnetic motor, comprising a 3-phase electrical stator winding and X windings per phase, connected in series or in parallel, characterised in comprising a circular wire guide with slots designed to hold the ends of the wires of the windings and a connector support comprising at least three circular connector tracks, three of said tracks being each terminated with a thimble and which are axially extended by wire grips to ensure the electrical contact for the 3 phases of the motor through the slots of the wire guides and wherein the thimbles exit the motor via a connector.

Abstract: A container for housing a therapeutic agent includes a body member, a sealing element, and a rupturable membrane. The body member has a proximal end and a distal end and a lumen that extends from the proximal end to the distal end. The sealing element is slidably disposable in the lumen. The sealing element is configured to sealingly engage the body member as the element is slid within the lumen. The rupturable membrane is disposed across the lumen in proximity to the distal end of the body member.

Abstract: A delivery system for delivering a therapeutic agent to a patient includes a catheter, a stop feature, a container and a bar. The catheter has a proximal end and a distal end and includes a body defining a lumen that extends to the distal end of the catheter. The stop feature is in proximity to the distal end of the catheter. The container is configured to house the therapeutic agent and is insertable and slidably disposable in the lumen of the catheter. The container is also configured to engage the stop feature of the catheter. The bar is slidably disposable in the lumen of the catheter. Sliding of the bar distally in the lumen forces the therapeutic agent out of the container and out of the lumen when the container is engaged with the stop feature. The stop feature is configured to inhibit the container from exiting the lumen.