Patents by Inventor Daniel V. Zurawski

Daniel V. Zurawski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MONOCLONAL ANTIBODIES FOR TREATMENT OF MICROBIAL INFECTIONS
    Publication number: 20210206840
    Abstract: In this application is described a mutant Acinobacter baumannii strain having a deletion or mutation in its genome. The deletion or mutation interrupts the proper translation of the Hcp protein.
    Type: Application
    Filed: March 3, 2021
    Publication date: July 8, 2021
    Applicant: The Government of The United States, as represented by The Secretary of The Army
    Inventor: Daniel V Zurawski
  • Monoclonal antibodies for treatment of microbial infections
    Patent number: 10961298
    Abstract: Described are a therapeutic monoclonal antibody specific for the Type Six Secretion System (T6SS) needle protein of Acinetobacter baumannii (A. baumannii) and methods of use. Specifically, the antibody specifically binds to hemolysin co-regulated protein (Hep). Further disclosed are methods of using an anti-Hep antibody for detecting A. baumannii in a sample as well as a mutant A. baumannii strain comprising a deletion or mutation in its genome such that said deletion or mutation interrupts the proper translation of its hep protein.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: March 30, 2021
    Assignee: The Government of The United States, Represented by the Secretary of the Army
    Inventor: Daniel V. Zurawski
  • MONOCLONAL ANTIBODIES FOR TREATMENT OF MICROBIAL INFECTIONS
    Publication number: 20170240618
    Abstract: Described are a therapeutic monoclonal antibody specific for the Type Six Secretion System (T6SS) needle protein of Acinetobacter baumannii (A. baumannii) and methods of use. Specifically, the antibody specifically binds to hemolysin co-regulated protein (Hep). Further disclosed are methods of using an anti-Hep antibody for detecting A. baumannii in a sample as well as a mutant A. baumannii strain comprising a deletion or mutation in its genome such that said deletion or mutation interrupts the proper translation of its hep protein.
    Type: Application
    Filed: August 21, 2015
    Publication date: August 24, 2017
    Inventor: Daniel V. Zurawski
  • MURINE WOUND MODEL FOR TESTING PATHOGEN VIRUENCE AND THERAPEUTIC EFFICACY
    Publication number: 20170173186
    Abstract: The invention provides a murine model of wound infection and biofilm formation and methods for producing such model. The inventive murine model of wound infection may be used to evaluate pathogen virulence and test efficacy of a pharmaceutical composition and/or a treatment procedures in preventing or treating wound infection, reducing biofilm formation, or reducing symptoms in a subject.
    Type: Application
    Filed: December 15, 2014
    Publication date: June 22, 2017
    Inventors: Rebecca L. Pavlicek, Daniel V. Zurawski, Mitchell G. Thompson, Chad C. Black
  • MURINE WOUND MODEL FOR TESTING PATHOGEN VIRUENCE AND THERAPEUTIC EFFICACY
    Publication number: 20160166712
    Abstract: The invention provides a murine model of wound infection and biofilm formation and methods for producing such model. The inventive murine model of wound infection may be used to evaluate pathogen virulence and test efficacy of a pharmaceutical composition and/or a treatment procedures in preventing or treating wound infection, reducing biofilm formation, or reducing symptoms in a subject.
    Type: Application
    Filed: December 15, 2014
    Publication date: June 16, 2016
    Inventors: Rebecca L. Pavlicek, Daniel V. Zurawski, Mitchell G. Thompson, Chad C. Black