Patents by Inventor Daniele Bonadeo

Daniele Bonadeo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Treating Centrally Mediated Nausea and Vomiting
    Publication number: 20120064153
    Abstract: Provided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
    Type: Application
    Filed: March 31, 2011
    Publication date: March 15, 2012
    Applicant: HELSINN HEALTHCARE SA
    Inventors: Fabio Trento, Sergio Cantoreggi, Giorgia Rossi, Roberta Cannella, Daniele Bonadeo, Riccardo Braglia
  • Liquid Pharmaceutical Formulations of Palonosetron
    Publication number: 20110192493
    Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.
    Type: Application
    Filed: April 14, 2011
    Publication date: August 11, 2011
    Applicants: Helsinn Healthcare S.A., Roche Palo Alto LLC
    Inventors: Giorgio Calderari, Daniele Bonadeo, Roberta Cannella, Enrico Braglia, Riccardo Braglia, Andrew Miksztal, Thomas Malefyt, Kathleen M. Lee
  • Liquid pharmaceutical formulations of palonosetron
    Patent number: 7960424
    Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.
    Type: Grant
    Filed: March 24, 2006
    Date of Patent: June 14, 2011
    Assignees: Helsinn Healthcare S.A., Roche Palo Alto LLC
    Inventors: Giorgio Calderari, Daniele Bonadeo, Roberta Cannella, Enrico Braglia, Riccardo Braglia, Andrew Miksztal, Thomas Malefyt, Kathleen M. Lee
  • Liquid pharmaceutical formulations of palonosetron
    Patent number: 7947725
    Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.
    Type: Grant
    Filed: March 24, 2006
    Date of Patent: May 24, 2011
    Assignees: Helsinn Healthcare S.A., Roche Palo Alto LLC
    Inventors: Giorgio Calderari, Daniele Bonadeo, Roberta Cannella, Enrico Braglia, Riccardo Braglia, Andrew Miksztal, Thomas Malefyt, Kathleen M. Lee
  • Liquid pharmaceutical formulations of palonosetron
    Patent number: 7947724
    Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: May 24, 2011
    Assignees: Helsinn Healthcare S.A., Roche Palo Alto LLC
    Inventors: Giorgio Calderari, Daniele Bonadeo, Roberta Cannella, Enrico Braglia, Riccardo Braglia, Andrew Miksztal, Thomas Malefyt, Kathleen M. Lee
  • Dosage Forms of Palonosetron Hydrochloride Having Improved Stability and Bioavailability
    Publication number: 20080152704
    Abstract: Provided are solid oral dosage forms of palonosetron hydrochloride, methods of using the dosage forms to treat emesis, and methods of making the dosage forms. The dosage forms have improved stability and bioavailability, and are preferably in the form of liquid filled capsules.
    Type: Application
    Filed: October 24, 2007
    Publication date: June 26, 2008
    Inventors: Daniele Bonadeo, Giorgio Calderari, Enrico Braglia, Riccardo Braglia
  • Liquid pharmaceutical formulations of palonosetron
    Publication number: 20060167072
    Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.
    Type: Application
    Filed: March 24, 2006
    Publication date: July 27, 2006
    Applicant: Helsinn Healthcare SA
    Inventors: Giorgio Calderari, Daniele Bonadeo, Roberta Cannella, Enrico Braglia, Riccardo Braglia
  • Liquid pharmaceutical formulations of palonosetron
    Publication number: 20060167073
    Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.
    Type: Application
    Filed: March 24, 2006
    Publication date: July 27, 2006
    Applicant: Helsinn Healthcare SA
    Inventors: Giorgio Calderari, Daniele Bonadeo, Roberta Cannella, Enrico Braglia, Riccardo Braglia
  • Liquid pharmaceutical formulations of palonosetron
    Publication number: 20060167071
    Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.
    Type: Application
    Filed: March 24, 2006
    Publication date: July 27, 2006
    Applicant: Helsinn Healthcare SA
    Inventors: Giorgio Calderari, Daniele Bonadeo, Roberta Cannella, Enrico Braglia, Riccardo Braglia
  • Liquid pharmaceutical formulations of palonosetron
    Publication number: 20060069114
    Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.
    Type: Application
    Filed: July 21, 2005
    Publication date: March 30, 2006
    Applicant: Helsinn Healthcare SA
    Inventors: Giorgio Calderari, Daniele Bonadeo, Roberta Cannella, Enrico Braglia, Riccardo Braglia
  • Process for the preparation of a granulate suitable to the preparation of rapidly disintegrable mouth-soluble tablets and compositions obtained thereby
    Patent number: 6149938
    Abstract: A process for making a granulate composition suitable to the preparation of an oral solid form that can disintegrate rapidly inside the buccal cavity is provided as well as the granulate compositions and obtained.
    Type: Grant
    Filed: July 23, 1998
    Date of Patent: November 21, 2000
    Assignee: Elan Pharma International Limited
    Inventors: Daniele Bonadeo, Franco Ciccarello, Aberto Pagano
  • Liquid pharmaceutical composition for oral use containing 2-(4-isobutylphenyl) propionic acid
    Patent number: 6005005
    Abstract: A liquid pharmaceutical composition for oral use containing 2-(4-isobutylphenyl)-propionic acid, as the active ingredient, and arginine is described.
    Type: Grant
    Filed: June 15, 1994
    Date of Patent: December 21, 1999
    Assignee: Zambon Group S.p.A.
    Inventors: Federico Stroppolo, Daniele Bonadeo, Luigi Vigano', Annibale Gazzaniga, deceased, by Paola Maria Gazzaniga, legal representative
  • Solid pharmaceutical compositions containing (S)-2-(4-isobutylphenyl) propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients
    Patent number: 5869102
    Abstract: The present invention relates to a solid pharmaceutical composition containing (S)-2-(4-isobutylphenyl) propionic acid as active ingredient and it relates to a solid pharmaceutical composition suitable for the preparation of pharmaceutical forms in tablets, sachets and capsules containing (S)-2-(4-isobutylphenyl)-propionic acid as active ingredient. This formulation in tablets contains (S)-Ibupropen, colloidal silica as disintegrating agent, microcrystalline cellulose as diluent and magnesium stearate as lubricant. Tablets are prepared by direct compression of the pharmaceutical composition object of the present invention and may be coated or filmed according to conventional techniques.
    Type: Grant
    Filed: November 27, 1996
    Date of Patent: February 9, 1999
    Assignee: Zambon Group, S.p.A.
    Inventors: Federico Stroppolo, Daniele Bonadeo, Alberto Pagano, Annibale Gazzaniga, deceased, Paola Maria Gazzaniga, legal representative
  • Syrup containing N-acetyl-cysteine
    Patent number: 5807894
    Abstract: A syrup containing N-acetyl-cysteine, stable for at least two years, having pleasant taste and smell, consists of an aqueous solution of NAC, a sweetening agent and a thickening agent. The solution can also contain a flavoring agent and a preservative. The pH is between 5 and 8.
    Type: Grant
    Filed: June 3, 1997
    Date of Patent: September 15, 1998
    Assignee: Zambon Group S.p.A.
    Inventors: Federico Stroppolo, Daniele Bonadeo, Alessandro Saudino, Annibale Gazzaniga
  • Pharmaceutical compositions for topical use containing (S)-2-(4-isobutylphenyl) propinonic acid
    Patent number: 5767161
    Abstract: A pharmacuetical composition in the form of cream, foam or stick containng 2.5-10% by weight (S)-2-(4-isobutylphenyl)propionic acid, 20-30% by weight and ethanol and 5-50% by weight propylene glycol, the ratio of ethanol to propylene glycol being 0.6-1 to 4:1.
    Type: Grant
    Filed: May 30, 1996
    Date of Patent: June 16, 1998
    Assignee: Zambon Group S.P.A.
    Inventors: Federico Stroppolo, Daniele Bonadeo, Alberto Riccardi, Annibale Gazzaniga, deceased, Paola Maria Gazzaniga, legal representative
  • Pharmaceutical composition having analgesic activity
    Patent number: 5693312
    Abstract: Pharmaceutical compositions having analgesic activity containing (S)-2-(6-methoxy-2-naphthyl)-propionic acid as active ingredient and arginine, useful for the preparation of pharmaceutical forms for oral route, are described,
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 2, 1997
    Assignee: Zambon Group S.p.A.
    Inventors: Federico Stroppolo, Daniele Bonadeo, Luigi Vigano, Annibale Gazzaniga
  • Pharmaceutical composition having analgesic activity
    Patent number: 5645857
    Abstract: A pharmaceutical composition for oral use having analgesic activity containing a mixture of arginine and (S)-Ibuprofen in a molar ratio between 1.1 and 1.9 is described.
    Type: Grant
    Filed: October 27, 1995
    Date of Patent: July 8, 1997
    Assignee: Zambon Group S.p.A.
    Inventors: Federico Stroppolo, Daniele Bonadeo, Gian Franco Fornasini, Annibale Gazzaniga
  • Ophthalmic pharmaceutical composition containing N-acetyl-cysteine and polyvinylalcohol
    Patent number: 5510101
    Abstract: An ophthalmic pharmaceutical composition containing an association of N-acetyl-cysteine and polyvinylalcohol useful for the treatment of keratoconjunctivitis sicca.
    Type: Grant
    Filed: March 17, 1994
    Date of Patent: April 23, 1996
    Assignee: Zambon Group S.p.A.
    Inventors: Federico Stroppolo, Daniele Bonadeo, Francesco Tocchini, Annibale Gazzaniga
  • Pharmaceutical compositions containing the salts of S(+)-2-(4-isobutylphenyl)propionic acid with basic aminoacids
    Patent number: 5510385
    Abstract: A pharmaceutical composition for oral use containing the salt of S(+)-2-(4-isobutylphenyl)propionic acid with a basic aminoacid selected between L-arginine and L-lysine is described.
    Type: Grant
    Filed: June 7, 1994
    Date of Patent: April 23, 1996
    Assignee: Zambon Group S.p.A.
    Inventors: Federico Stroppolo, Daniele Bonadeo, Gian F. Fornasini, Annibale Gazzaniga
  • Capsule for pharmaceutical products
    Patent number: D665072
    Type: Grant
    Filed: September 8, 2011
    Date of Patent: August 7, 2012
    Assignee: Helsinn Healthcare S.A.
    Inventors: Fabio Trento, Sergio Cantoreggi, Giorgia Rossi, Roberta Cannella, Daniele Bonadeo, Riccardo Braglia