Patents by Inventor Danilo D. Lasic

Danilo D. Lasic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Liposomes containing an entrapped compound in supersaturated solution
    Patent number: 8062662
    Abstract: A liposome composition having a compound entrapped in a supersaturated solution and method for preparing such a composition are described.
    Type: Grant
    Filed: March 16, 2006
    Date of Patent: November 22, 2011
    Assignees: Alza Corporation, Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Danilo D. Lasic, Robert M. Abra, Yechezkel Barenholz, Tal Peleg-Shulman
  • Liposomes containing an entrapped compound in supersaturated solution
    Publication number: 20010033861
    Abstract: A liposome composition having a compound entrapped in a supersaturated solution and method for preparing such a composition are described.
    Type: Application
    Filed: January 26, 2001
    Publication date: October 25, 2001
    Inventors: Danilo D. Lasic, Robert M. Abra, Yechezkel Barenholz, Tal Peleg-Shulman
  • Lipid-polymer conjugates and liposomes
    Patent number: 5631018
    Abstract: A lipid-polymer conjugate for use in forming long-circulating liposomes is disclosed. The conjugate includes a vesicle-forming lipid having covalently attached to its polar head group, one of the polymers: polyvinylpyrrolidone, polyvinylmethylether, polyhydroxypropyl methacrylate, polyhydroxypropylmethacrylamide, polyhydroxyethyl acrylate, polymethacrylamide, polydimethylacrylamide, polymethyloxazoline, polyethyloxazoline, polyhydroxyethyloxazoline, polyhydroxypropyloxazoline, or polyaspartamide. A method for preparing liposomes containing the lipid-polymer conjugate is also disclosed.
    Type: Grant
    Filed: October 4, 1994
    Date of Patent: May 20, 1997
    Assignee: Sequus Pharmaceuticals, Inc.
    Inventors: Samuel Zalipsky, Martin C. Woodle, Danilo D. Lasic, Francis J. Martin
  • Lipid-polymer conjugates and liposomes
    Patent number: 5395619
    Abstract: A lipid-polymer conjugate for use in forming long-circulating liposomes is disclosed. The conjugate includes a vesicle-forming lipid having covalently attached to its polar head group, one of the polymers: polyvinylpyrrolidone, polyvinylmethylether, polyhydroxypropyl methacrylate, polyhydroxypropylmethacrylamide, polyhydroxyethyl acrylate, polymethacrylamide, polydimethylacrylamide, polymethyloxazoline, polyethyloxazoline, polyhydroxyethyloxazoline, polyhydroxypropyloxazoline, or polyaspartamide. A method for preparing liposomes containing the lipid-polymer conjugate is also disclosed.
    Type: Grant
    Filed: March 3, 1993
    Date of Patent: March 7, 1995
    Assignee: Liposome Technology, Inc.
    Inventors: Samuel Zalipsky, Martin C. Woodle, Danilo D. Lasic, Francis J. Martin
  • Method for instant preparation of a drug containing large unilamellar vesicles
    Patent number: 5185154
    Abstract: This invention describes a simple, fast, reproducible economic, and convenient method of preparation of very large unilamellar liposome vesicles of uniform size distribution. The populations of these vesicles are homogeneous and suitable for encapsulation of water and lipid soluble compounds.
    Type: Grant
    Filed: February 28, 1990
    Date of Patent: February 9, 1993
    Assignee: Liposome Technology, Inc.
    Inventors: Danilo D. Lasic, Andrej Belic