Patents by Inventor Daria Zielinska

Daria Zielinska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of Protected 3'-amino Nucleoside Monomers
    Publication number: 20240034748
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Application
    Filed: December 2, 2022
    Publication date: February 1, 2024
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • Synthesis of Protected 3'-amino Nucleoside Monomers
    Publication number: 20230089101
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Application
    Filed: May 25, 2022
    Publication date: March 23, 2023
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • Synthesis of Protected 3'-Amino Nucleoside Monomers
    Publication number: 20200377543
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Application
    Filed: July 31, 2020
    Publication date: December 3, 2020
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • Synthesis of protected 3?-amino nucleoside monomers
    Patent number: 10738073
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: August 11, 2020
    Assignee: Geron Corporation
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • Synthesis of Protected 3'-Amino Nucleoside Monomers
    Publication number: 20190031707
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Application
    Filed: June 29, 2018
    Publication date: January 31, 2019
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • Synthesis of protected 3?-amino nucleoside monomers
    Patent number: 10035815
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: July 31, 2018
    Assignee: Geron Corporation
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • C-myc antisense oligonucleotides and methods for using the same to treat cell-proliferative disorders
    Patent number: 9771581
    Abstract: Provided herein are antisense oligonucleotides that can effectively prevent or decrease c-myc protein expression as well as decrease overall rates of cell proliferation in in vitro and mammalian in vivo models of cell proliferative disorders as well as methods for using the same.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: September 26, 2017
    Assignee: Geron Corporation
    Inventors: Sergei M. Gryaznov, Daria Zielinska, Ronald A. Pruzan, Jeffrey N. Lindquist
  • Synthesis of Protected 3'-Amino Nucleoside Monomers
    Publication number: 20160362440
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Application
    Filed: May 16, 2016
    Publication date: December 15, 2016
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • C-MYC ANTISENSE OLIGONUCLEOTIDES AND METHODS FOR USING THE SAME TO TREAT CELL-PROLIFERATIVE DISORDERS
    Publication number: 20160186173
    Abstract: Provided herein are antisense oligonucleotides that can effectively prevent or decrease c-myc protein expression as well as decrease overall rates of cell proliferation in in vitro and mammalian in vivo models of cell proliferative disorders as well as methods for using the same.
    Type: Application
    Filed: December 2, 2015
    Publication date: June 30, 2016
    Inventors: Sergei M. GRYAZNOV, Daria ZIELINSKA, Ronald A. PRUZAN, Jeffrey N. LINDQUIST
  • Synthesis of protected 3?-amino nucleoside monomers
    Patent number: 9365606
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: June 14, 2016
    Assignee: Geron Corporation
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • C-myc antisense oligonucleotides and methods for using the same to treat cell-proliferative disorders
    Patent number: 9228189
    Abstract: Provided herein are antisense oligonucleotides that can effectively prevent or decrease c-myc protein expression as well as decrease overall rates of cell proliferation in in vitro and mammalian in vivo models of cell proliferative disorders as well as methods for using the same.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: January 5, 2016
    Assignee: Geron Corporation
    Inventors: Sergei M. Gryaznov, Daria Zielinska, Ronald A. Pruzan, Jeffrey N. Lindquist
  • SYNTHESIS OF PROTECTED 3'-AMINO NUCLEOSIDE MONOMERS
    Publication number: 20150038692
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Application
    Filed: May 13, 2014
    Publication date: February 5, 2015
    Applicant: Geron Corporation
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • Synthesis of protected 3?-amino nucleoside monomers
    Patent number: 8748593
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: June 10, 2014
    Assignee: Geron Corporation
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • C-MYC ANTISENSE OLIGONUCLEOTIDES AND METHODS FOR USING THE SAME TO TREAT CELL-PROLIFERATIVE DISORDERS
    Publication number: 20140121261
    Abstract: Provided herein are antisense oligonucleotides that can effectively prevent or decrease c-myc protein expression as well as decrease overall rates of cell proliferation in in vitro and mammalian in vivo models of cell proliferative disorders as well as methods for using the same.
    Type: Application
    Filed: March 14, 2013
    Publication date: May 1, 2014
    Inventors: Sergei M. GRYAZNOV, Daria Zielinska, Ronald A. Pruzan, Jeffrey N. Lindquist
  • Synthesis of Protected 3'-Amino Nucleoside Monomers
    Publication number: 20090105468
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Application
    Filed: December 22, 2008
    Publication date: April 23, 2009
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • Synthesis of protected 3?-amino nucleoside monomers
    Patent number: 7485717
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Grant
    Filed: June 30, 2005
    Date of Patent: February 3, 2009
    Assignee: Geron Corporation
    Inventors: Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
  • Synthesis of protected 3'-amino nucleoside monomers
    Publication number: 20060009636
    Abstract: Orthogonally protected 3?-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3?-amino group in the presence of the unprotected nucleoside base.
    Type: Application
    Filed: June 30, 2005
    Publication date: January 12, 2006
    Inventors: Sergei Gryaznov, Krisztina Pongracz, Daria Zielinska