Patents by Inventor Darin DuMez

Darin DuMez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for delivery of hydrophobic active agents
    Patent number: 11246963
    Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In an embodiment, the invention includes a drug delivery device including a substrate; and coated therapeutic agent particles disposed on the substrate, the coated therapeutic agent particles comprising a particulate hydrophobic therapeutic agent; and a vinyl amine polymer. Methods of making the delivery composition, as well as kits and methods of use are also included herein.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: February 15, 2022
    Assignee: Surmodics, Inc.
    Inventors: Joram Slager, Dale G. Swan, Darin DuMez, Joseph Ventura, Shannon Wadman, Joseph Schmidt McGonigle, Robert W. Hergenrother
  • Bioerodable poly(etheresteramides) and medical article uses
    Patent number: 9375519
    Abstract: Bioerodable poly(etheresteramides) and matrices formed therefrom, such as medical device coatings, are described. The matrices show desirable erosion properties desirable for therapeutic use. The matrices can include a bioactive agent which can be used to treat medical conditions.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: June 28, 2016
    Assignee: SurModics, Inc.
    Inventors: Kyle Eastenson, Aleksey V. Kurdyumov, Darin DuMez, Klaus Wormuth, Nathan A. Lockwood
  • COMPOSITIONS AND METHODS FOR DELIVERY OF HYDROPHOBIC ACTIVE AGENTS
    Publication number: 20140336571
    Abstract: Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In an embodiment, the invention includes a drug delivery device including a substrate; and coated therapeutic agent particles disposed on the substrate, the coated therapeutic agent particles comprising a particulate hydrophobic therapeutic agent; and a vinyl amine polymer. Methods of making the delivery composition, as well as kits and methods of use are also included herein.
    Type: Application
    Filed: May 16, 2014
    Publication date: November 13, 2014
    Applicant: SurModics, Inc.
    Inventors: Joram Slager, Dale G. Swan, Darin DuMez, Joseph Ventura, Shannon Wadman, Joseph Schmidt McGonigle, Robert W. Hergenrother
  • BIOERODABLE POLY(ETHERESTERAMIDES) AND MEDICAL ARTICLE USES
    Publication number: 20130344126
    Abstract: Bioerodable poly(etheresteramides) and matrices formed therefrom, such as medical device coatings, are described. The matrices show desirable erosion properties desirable for therapeutic use. The matrices can include a bioactive agent which can be used to treat medical conditions.
    Type: Application
    Filed: June 25, 2013
    Publication date: December 26, 2013
    Inventors: Kyle Eastenson, Aleksey V. Kurdyumov, Darin DuMez, Klaus Wormuth