Patents by Inventor Darin J. Falk

Darin J. Falk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating diseases
    Patent number: 11261460
    Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: March 1, 2022
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Barry John Byrne, Darin J. Falk, Christina Pacak, Lara Robert DeRuisseau, Cathryn Mah, David D. Fuller
  • COMPOSITIONS AND METHODS FOR TREATING DISEASES
    Publication number: 20210145906
    Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.
    Type: Application
    Filed: December 31, 2020
    Publication date: May 20, 2021
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Barry John Byrne, Darin J. Falk, Christina Pacak, Lara Robert DeRuisseau, Cathryn Mah, David D. Fuller
  • Compositions and methods for treating diseases
    Patent number: 10912804
    Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: February 9, 2021
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Barry John Byrne, Darin J. Falk, Christina Pacak, Lara Robert DeRuisseau, Cathryn Mah, David D. Fuller
  • COMPOSITIONS AND METHODS FOR TREATING DISEASES
    Publication number: 20180051299
    Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.
    Type: Application
    Filed: January 13, 2016
    Publication date: February 22, 2018
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Barry John Byrne, Darin J. Falk, Christina Pacak, Lara Robert Deruisseau, Cathryn Mah, David D. Fuller
  • METHODS OF PERMITTING A SUBJECT TO RECEIVE MULTIPLE DOSES OF RECOMBINANT ADENO-ASSOCIATED VIRUS
    Publication number: 20170049887
    Abstract: Provided herein are compositions, kits and methods related to permitting a human or non-human primate subject to receive multiple doses of recombinant adeno-associate virus (rAAV) vectors. In some aspects, provided herein are methods comprising administering an anti-CD20 antibody, optionally in combination with an mTOR inhibitor, to the subject to permit multiple doses of an rAAV vector to be administered.
    Type: Application
    Filed: April 24, 2015
    Publication date: February 23, 2017
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Barry John Byrne, Darin J. Falk, Manuela Corti
  • COMPOSITIONS AND METHODS FOR TREATING DISEASES
    Publication number: 20170028002
    Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.
    Type: Application
    Filed: April 1, 2016
    Publication date: February 2, 2017
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Barry John Byrne, Darin J. Falk, Christina Pacak, Lara Robert Deruisseau, Cathryn Mah, David D. Fuller
  • COMPOSITIONS AND METHODS FOR TREATING DISEASES
    Publication number: 20160369297
    Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.
    Type: Application
    Filed: January 13, 2016
    Publication date: December 22, 2016
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Barry John Byrne, Darin J. Falk, Christina Pacak, Lara Robert Deruisseau, Cathryn Mah, David D. Fuller
  • COMPOSITIONS AND METHODS FOR TREATING DISEASES
    Publication number: 20150196671
    Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.
    Type: Application
    Filed: June 19, 2013
    Publication date: July 16, 2015
    Inventors: Barry John Byrne, Darin J. Falk, Christina Pacak, Lara Robert Deruisseau, Cathryn Mah, David D. Fuller
  • Compositions and Methods for Treating Diseases
    Publication number: 20120322861
    Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.
    Type: Application
    Filed: June 19, 2012
    Publication date: December 20, 2012
    Inventors: Barry John BYRNE, Darin J. Falk, Christina A. Pacak, Lara Robert DeRuisseau, Cathryn Mah, David D. Fuller