Abstract: A high-pressure connection in a conduit or enclosure utilizing a bidirectional, pressure-energized seal. Male and female flanges are provided, where one of the flanges has a recess that accommodates a seal ring. The outer peripheries of the two flanges' sealing surfaces are in contact with each so that clamping, bolting and bending stresses are not borne by the seal ring. The seal ring has a cross-section that includes a solid body and two V shaped sealing portions that extend from the body at an angle between 90 and 160 degrees. Each sealing portion has a set of opposing sealing faces with a cavity between them, so that fluid pressure within the cavity urges the sealing faces outward from the first cavity toward the flanges.