Patents by Inventor Dario Tentorio

Dario Tentorio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for preparing palonosetron salts
    Patent number: 7737280
    Abstract: The present invention provides processes for preparing Palonosetron salts, especially, the hydrochloride salt and intermediates used to prepare Palonosetron salts.
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: June 15, 2010
    Assignee: Sicor Inc.
    Inventors: Pierluigi Rossetto, Peter MacDonald, Ettore Bigatti, Gaia Banfi, Dario Tentorio
  • Imatinib base, and imatinib mesylate and processes for preparation thereof
    Publication number: 20080207904
    Abstract: The present invention provides crystalline forms of imatinib base, imatinib base free of desmethyl imatinib, and imatinib mesylate free of desmethyl imatinib mesylate, processes of their preparation and pharmaceutical compositions of imatinib mesylate.
    Type: Application
    Filed: October 26, 2007
    Publication date: August 28, 2008
    Inventors: Peter MacDonald, Pierluigi Rossetto, Alexandr Jegorov, Andrea Giolito, Dario Tentorio, Augusto Canavesi
  • Processes for preparing palonosetron salts
    Publication number: 20080200681
    Abstract: The present invention provides processes for preparing Palonosetron salts, especially, the hydrochloride salt and intermediates used to prepare Palonosetron salts.
    Type: Application
    Filed: October 23, 2007
    Publication date: August 21, 2008
    Inventors: Pierluigi Rossetto, Peter MacDonald, Ettore Bigatti, Gaia Banfi, Dario Tentorio
  • Process for the enzymatic kinetic resolution of 3-phenylglycidates by transesterification with aminoalcohols
    Patent number: 6187936
    Abstract: A process for the preparation of I: in which R and R1 have the meanings reported in the description, that comprises the enzymatic kinetic resolution by transesterification with aminoalcohols of 3-phenylglycidates of formula I: is described.
    Type: Grant
    Filed: September 20, 1999
    Date of Patent: February 13, 2001
    Assignee: Zambon Group S.p.A.
    Inventors: Marco Villa, Dario Tentorio, Angelo Restelli, Sergio Riva
  • Process for the single crystallization of enatiomeric ratio's (2S,3S):(2R,3R) of substituted 1,5-benzothiazepinone
    Patent number: 5315005
    Abstract: A purification method of intermediates for the preparation of Diltiazem which consists of the crystallization of a mixture enantiomerically enriched in (2S,3S)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H) -one is described.
    Type: Grant
    Filed: January 25, 1993
    Date of Patent: May 24, 1994
    Assignee: Zambon Group S.p.A.
    Inventors: Claudio Giordano, Dario Tentorio, Laura Russo
  • Mono (2-ammonium-2-hydroxymethyl-1,3-propanediol) (2R,cis)-1,2-epoxypropyl-phosphonate with improved characteristics of stability and processing
    Patent number: 5191094
    Abstract: A process is described for the preparation of mono (2-ammonium-2-hydroxymethyl-1,3-propanediol) (2R,cis)-1,2-epoxypropyl-phosphonate with improved characteristics of stability, of processing for the preparation of pharmaceutical forms and of stability of the pharmaceutical forms that contain it.
    Type: Grant
    Filed: June 11, 1992
    Date of Patent: March 2, 1993
    Assignee: Zambon Group S.p.A.
    Inventors: Dario Tentorio, Graziano Castaldi, Claudio Girodano, Franco Pozzi
  • Mono (2-ammonium-2-hydroxymethyl-1,3-propanediol)(2R,cis)-1,2-ep-oxipropyl-ph osphonate with improved characteristics of stability and processing
    Patent number: 5162309
    Abstract: A process is described for the preparation of mono (2-ammonium-2-hydroxymethyl-1,3-propanediol) (2R,cis)-1,2-epoxypropyl-phosphonate with improved characteristics of stability, of processing for the preparation of pharmaceutical forms and of stability of the pharmaceutical forms that contain it.
    Type: Grant
    Filed: July 25, 1990
    Date of Patent: November 10, 1992
    Assignee: Zambon Group
    Inventors: Dario Tentorio, Graziano Castaldi, Claudio Giordano, Franco Pozzi
  • Process for the resolution of intermediates useful in the preparation of 1,5-benzothiazepines
    Patent number: 5144025
    Abstract: A process for the resolution of amminoesters of the formula ##STR1## wherein R.sub.1 and R.sub.3 have the meanings reported in the specification, by tartaric acid and analogs thereof, is described. The compounds of formula IV-A are intermediates useful in the preparation of optically active (2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)ones.
    Type: Grant
    Filed: April 5, 1990
    Date of Patent: September 1, 1992
    Assignee: Zambon Group S.p.A.
    Inventor: Dario Tentorio
  • Resolution process of intermediates useful for the preparation of diltiazem
    Patent number: 5097059
    Abstract: A process of spontaneous resolution of compounds of formula ##STR1## wherein R has the meanings reported in the description, is described. The compounds of formula III are intermediates useful for the preparation of Diltiazem.
    Type: Grant
    Filed: July 26, 1990
    Date of Patent: March 17, 1992
    Assignee: Zambon Group S.p.A.
    Inventors: Claudio Giordano, Dario Tentorio, Roberto Casagrande, Placido Bertin, Valeriano Merli, Giorgio Sagramora