Patents by Inventor Dariusz Cieslak

Dariusz Cieslak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of tumor growth by antisense oligonucleotides for IL-8 and IL-8 receptor
    Patent number: 6017898
    Abstract: Oligonucleotides are provided which are effective in inhibiting the growth, metastasis and/or angiogenesis of tumors, including particularly melanoma and/or lung cancer. Methods are also provided for use of these oligonucleotides in the treatment of diseases.
    Type: Grant
    Filed: April 6, 1998
    Date of Patent: January 25, 2000
    Assignee: ICN Pharmaceuticals, Inc.
    Inventors: Zbigniew Pietrzkowski, Dariusz Cieslak, Gordana Olbina
  • Control of CD44 gene expression for therapeutic use
    Patent number: 5990299
    Abstract: Neoplastic cells which over-express CD44, including especially non-small cell lung cancer and melanoma cancer cells, are treated with antisense oligonucleotides to control CD44 expression. Test results show that the claimed oligonucleotides significantly decreases cell growth in a CD44 sequence specific manner of lung cancer or melanoma cells, or both, but are largely non-toxic to normal cells. Examples of dosing in a clinical setting are provided.
    Type: Grant
    Filed: August 14, 1995
    Date of Patent: November 23, 1999
    Assignee: ICN Pharmaceuticals, Inc.
    Inventors: Sabera Ruzdijic, Zbigniew Pietrzkowski, Dariusz Cieslak
  • Antisense oligonucleotides for IL-8 and IL-8 receptor
    Patent number: 5849903
    Abstract: Oligonucleotides are provided which are effective in inhibiting the growth, metastasis and/or angiogenesis of tumors, including particularly melanoma and/or lung cancer. Methods are also provided for use of these oligonucleotides in the treatment of diseases.
    Type: Grant
    Filed: February 5, 1997
    Date of Patent: December 15, 1998
    Assignee: ICN Pharmaceuticals, Inc.
    Inventors: Zbigniew Pietrzkowski, Dariusz Cieslak, Gordana Olbina