Abstract: A method for providing localized treatment at a target site in the brain of a patient is provided. The method comprises providing a system comprising a miniature device configured to carry one or more therapeutic components for performing the treatment, and an external system configured to direct the miniature device; inserting the miniature device to a starting location within the patient; operating the external system to direct the miniature device to travel along an access path from the starting location to the target site; and administering the therapeutic component at the target site. A system for performing the method is further provided.

Abstract: A miniature device configured to be maneuvered within a patient under manipulation by an external magnetic field and to selectively perform a predefined function is provided. The miniature device comprises a shell defining therewithin an internal cavity, and a magnetic arrangement disposed within the cavity. The miniature device is configured such that the magnetic arrangement, within a rotating magnetic field, effects one of performance of the function and propulsion of the miniature device within the patient, and, within a magnetic field gradient, effects the other of performance of the function and propulsion of the miniature device within the patient.

Abstract: A miniature device is provided for use in a system configured to deliver a therapeutic component to a treatment site in a patient. The miniature device comprises at least one steering portion comprising a magnetic material, and at least one carrier portion affixed to the steering portion and comprising the therapeutic component. The carrier portion is configured to at least partially dissipate under one or more predetermined conditions at the treatment site, thereby releasing the therapeutic component. Further provided is a system comprising one or more such miniature devices and a magnetic inducing apparatus configured to be operated to generate a varying magnetic field, thereby remotely controlling motion of the miniature device.

Abstract: A method and apparatus for safely and reliably accessing a subarachnoid space (SAS) or other target area of a patient is provided in which a tube having at least one lumen with a tissue puncture device therein is inserted into the patient near the tissue. The lumen has a suction port at one end adapted to suction the dura/arachnoid tissue away from the pia mater so that the tissue can be punctured to access the SAS space. The movement of the needle in the lumen is controlled by controlling a magnetic field. Tissue puncture devices for use alone or in connection with the apparatus are also provided.

Abstract: A method for focusing a miniature camera includes providing a current through a coil, moving a lens of a camera based on the current to adjust a focus of the camera, and limiting movement of the lens along an optical path of the camera.

Abstract: A method for focusing a miniature camera includes providing a current through a coil, moving a lens of a camera based on the current to adjust a focus of the camera, and limiting movement of the lens along an optical path of the camera.

Abstract: A method for focusing a miniature camera includes providing a current through a coil, moving a lens of a camera based on the current to adjust a focus of the camera, and limiting movement of the lens along an optical path of the camera.

Abstract: A method for focusing a miniature camera includes providing a current through a coil, moving a lens of a camera based on the current to adjust a focus of the camera, and limiting movement of the lens along an optical path of the camera.

Abstract: A method for focusing a miniature camera includes providing a current through a coil, moving a lens of a camera based on the current to adjust a focus of the camera, and limiting movement of the lens along an optical path of the camera.

Abstract: A method for focusing a miniature camera includes providing a current through a coil, moving a lens of a camera based on the current to adjust a focus of the camera, and limiting movement of the lens along an optical path of the camera.

Abstract: A method for focusing a miniature camera includes providing a current through a coil, moving a lens of a camera based on the current to adjust a focus of the camera, and limiting movement of the lens along an optical path of the camera.

Abstract: A method and system for facilitating focusing of a miniature camera are disclosed. One or more lenses can be attached to a MEMS stage. The MEMS stage can be moved by a Lorentz actuator. The MEMS stage can be configured to limit movement of the lens(es) to a single degree of freedom to inhibit misalignment thereof with respect to an imaging sensor. The stage can be biased to a predefined position thereof, e.g., for focus at infinity. A metal cover can inhibit electromagnetic interference and can limit movement of the lens(es).

Abstract: In an example embodiment, a method for focusing a miniature camera includes applying a signal to an actuator in the camera, moving a MEMS stage movably supported by one or more flexures in response to the application of the signal, moving a lens in response to the moving of the MEMS stage, and limiting movement of the MEMS stage to substantially one degree of freedom corresponding to an optical axis of the lens.

Abstract: In an example embodiment, a method for focusing a miniature camera includes applying a signal to an actuator in the camera, moving a MEMS stage movably supported by one or more flexures in response to the application of the signal, moving a lens in response to the moving of the MEMS stage, and limiting movement of the MEMS stage to substantially one degree of freedom corresponding to an optical axis of the lens.

Abstract: A method and system for facilitating focusing of a miniature camera are disclosed. One or more lenses can be attached to a MEMS stage. The MEMS stage can be moved by a Lorentz actuator. The MEMS stage can be configured to limit movement of the lens(es) to a single degree of freedom to inhibit misalignment thereof with respect to an imaging sensor. The stage can be biased to a predefined position thereof, e.g., for focus at infinity. A metal cover can inhibit electromagnetic interference and can limit movement of the lens(es).

Abstract: A method and system for facilitating focusing of a miniature camera are disclosed. One or more lenses can be attached to a MEMS stage. The MEMS stage can be moved by a Lorentz actuator. The MEMS stage can be configured to limit movement of the lens(es) to a single degree of freedom to inhibit misalignment thereof with respect to an imaging sensor. The stage can be biased to a predefined position thereof, e.g., for focus at infinity. A metal cover can inhibit electromagnetic interference and can limit movement of the lens(es).

Abstract: In accordance with an embodiment of the present invention, an electrostatic actuator has a base having a plurality of base pillars formed thereon and has a stage having a plurality of stage pillars formed thereon. The controlled application of voltage signals to the base pillars and/or the stage pillars results in electrostatic force that effects movement of the stage with respect to the base.

Abstract: In accordance with an embodiment of the present invention, an electrostatic actuator has a base having a plurality of base pillars formed thereon and has a stage having a plurality of stage pillars formed thereon. The controlled application of voltage signals to the base pillars and/or the stage pillars results in electrostatic force that effects movement of the stage with respect to the base.

Abstract: A method and system for facilitating focusing of a miniature camera are disclosed. One or more lenses can be attached to a MEMS stage. The MEMS stage can be moved by a Lorentz actuator. The MEMS stage can be configured to limit movement of the lens(es) to a single degree of freedom to inhibit misalignment thereof with respect to an imaging sensor. The stage can be biased to a predefined position thereof, e.g., for focus at infinity. A metal cover can inhibit electromagnetic interference and can limit movement of the lens(es).

Abstract: A method and system for biasing focusing optics of a miniature camera in a predetermined position are disclosed. A spring can be used to bias the optics in a position for focus at infinity. Such biasing mitigates power consumption, provides a failsafe feature, and mitigates the detrimental effects associated with the use of autofocus upon a subject having fuzzy features.