Patents by Inventor Darren K. MacFarland

Darren K. MacFarland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metallofullerene contrast agents
    Patent number: 9233177
    Abstract: Endohedral metallofullerene compounds, which in water has a relaxivity of about 30 mM?1 S?1 to about 300 mM?1 S?1 and forms a dispersion in water with entities having an average hydrodynamic radius of less than about 20 nm.
    Type: Grant
    Filed: October 22, 2008
    Date of Patent: January 12, 2016
    Assignee: Luna Innovations Incorporated
    Inventors: Darren K. Macfarland, Robert P. Lenk, Rajesh Shukla, Kenneth L. Walker, Stephen R. Wilson, Zhiguo Zhou
  • Fullerene therapies for inflammation
    Patent number: 8680125
    Abstract: Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: March 25, 2014
    Assignee: Luna Innovations Incorporated
    Inventors: Christopher L. Kepley, Robert P. Lenk, Stephen R. Wilson, Zhiguo Zhou, Darren K. MacFarland
  • Fullerene therapies for inflammation
    Patent number: 8563585
    Abstract: Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: October 22, 2013
    Assignee: Luna Innovations, Incorporated
    Inventors: Christopher L. Kepley, Robert P. Lenk, Stephen R. Wilson, Zhiguo Zhou, Darren K. MacFarland
  • FULLERENE THERAPIES FOR INFLAMMATION AND INHIBITION OF BUILD-UP OF ARTERIAL PLAQUE
    Publication number: 20110251158
    Abstract: Described herein are methods for treating inflammatory disorders or for inhibiting the build-up of arterial plaque. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.
    Type: Application
    Filed: September 16, 2010
    Publication date: October 13, 2011
    Applicant: Luna Innovations Incorporated
    Inventors: Christopher L. KEPLEY, Robert P. LENK, Darren K. MACFARLAND, Zhiguo ZHOU
  • METALLOFULLERENE CONTRAST AGENTS
    Publication number: 20110124848
    Abstract: Endohedral metallofullerene compounds, which in water has a relaxivity of about 30 mM?1 S?1 to about 300 mM?1 S?1 and forms a dispersion in water with entities having an average hydrodynamic radius of less than about 20 nm.
    Type: Application
    Filed: October 22, 2008
    Publication date: May 26, 2011
    Applicant: LUNA INNOVATIONS INCORPORATED
    Inventors: Darren K. Macfarland, Robert P. Lenk, Rajesh Shukla, Kenneth L. Walker, Stephen R. Wilson, Zhiguo Zhou
  • NEW REACTIONS OF FULLERENES
    Publication number: 20110065944
    Abstract: A process for producing a fullerene derivative. The process comprises reacting a fullerene compound with a primary amine in the presence of a peroxide.
    Type: Application
    Filed: October 22, 2008
    Publication date: March 17, 2011
    Applicant: Luna Innovations Incorporated`
    Inventor: Darren K. Macfarland
  • FULLERENE THERAPIES FOR INFLAMMATION
    Publication number: 20110028522
    Abstract: Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.
    Type: Application
    Filed: March 3, 2009
    Publication date: February 3, 2011
    Applicant: LUNA INNOVATIONS INCORPORATED
    Inventors: Christopher L. Kepley, Robert P. Lenk, Stephen R. Wilson, Zhiguo Zhou, Darren K. MacFarland