Patents by Inventor Darryl N. Willett

Darryl N. Willett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the stimulation of cell growth and the inhibition of cell proliferation by the utilization of selenodithiols such as selenodiglutathione
    Patent number: 5118624
    Abstract: This invention relates to the inhibition of cell proliferation in mammalian host organisms. More particularly the invention relates to the utilization of selenodithiol compositions, particularly selenodiglutathione (GSSeSG) within a narrow concentration range, in which it is both effective as an inhibitor of cancer tumor cell proliferation in mammals, particularly in the prevention of neoplastic cell division in humans, while substantially non toxic outside this narrow range to the treated host organism. The invention also relates to a method for stimulating cellular proliferation at lower concentration of selenodiglutathione.
    Type: Grant
    Filed: November 30, 1989
    Date of Patent: June 2, 1992
    Assignee: The Ohio State University
    Inventors: Wayne B. Parrish, Darryl N. Willett, Francis A. Kralick, Gregory N. Orr
  • Method for the inhibition of the proliferation of cancer cells in a tumor sensitive to treatment with a selenodithiol by the injection into the tumor of a selenodithiol such as selenodiglutathione
    Patent number: 5104852
    Abstract: The invention discloses a biphasic method of treating cancer tumors sensitive to treatment with selenodithiols, which method comprises administering a specific amount of a selenodithiol to the cancer tumor whereby the cancer tumor cells die and the surrounding non-cancerous tissue exhibits cell proliferation in cells sensitive to selenodithiols. A range of ratios of selenodithiol concentration to tumor diameters or volume is claimed.
    Type: Grant
    Filed: January 22, 1991
    Date of Patent: April 14, 1992
    Assignee: The Ohio State University
    Inventors: Francis A. Kralick, Wayne B. Parrish, Darryl N. Willett