Abstract: A drive train includes a torque multiplier assembly and a torque limiter device. An output of the torque multiplying assembly is drivingly coupled to an input of the torque limiter device. An input of the drive train is configured to be driven by a driver handle and an output of the drive train is configured to rotate a driver. A counter-torque connector that is configured to engage a spinal fixation construct is coupled to a counter-torque handle to prevent rotation of the spinal fixation construct. A coupling between a component of the torque multiplier assembly and the counter-torque handle prevents rotation of the component. Torque input by the single user through the driving handle is simultaneously multiplied by the torque multiplier assembly and limited by the torque limiter device, while the single user simultaneously prevents the spinal fixation construct from rotating through the counter-torque handle.

Abstract: Formed compositions for application to a bone surface of a human or animal subject, comprising: a bone material; and a carrier comprising denatured demineralized bone, where the composition is formed into a shape suitable for administration to the bone. Methods are provided for making formed compositions for application to a bone surface of a human or animal subject comprise mixing a demineralized bone and water; heating the mixture to form a carrier; mixing the carrier with bone to form a moldable composition; and molding the moldable composition to produce a formed composition. Several apparatuses are provided in which to hydrate the formed bone composition. Methods of hydrating a formed bone composition are also provided.