Patents by Inventor David A. Ahlquist

David A. Ahlquist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detecting colorectal neoplasm
    Patent number: 11987847
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: May 21, 2024
    Assignees: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, EXACT SCIENCES CORPORATION
    Inventors: David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
  • Digital sequence analysis of DNA methylation
    Patent number: 11952633
    Abstract: The present invention relates to methods and compositions for determination of and uses of specific methylation patterns indicative of adenoma and carcinoma. In particular, the invention relates to analysis of defined CpG loci that are coordinately methylated in DNAs from cancer and adenoma samples, methods for identifying coordinately methylated loci, and methods of using analysis of coordinately methylated loci in one or more marker regions in the design of assays for adenoma and cancer.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: April 9, 2024
    Assignees: Exact Sciences Corporation, Mayo Foundation for Medical Research and Education
    Inventors: David A. Ahlquist, William R. Taylor, Hongzhi Zou, Graham P. Lidgard
  • DETECTING CERVICAL CANCER
    Publication number: 20240052425
    Abstract: Provided herein is technology for cervical cancer screening. In particular, provided herein are methods, compositions, and related uses for detecting the presence or absence of cervical cancer, cervical pre-cancers (e.g., cervix related in-situ adenocarcinoma, cervical intraepithelial neoplasia), and cervical cancer subtypes (e.g., cervical adenocarcinoma, squamous cell cervical cancer), or for discriminating cervical cancer from other types of gynecological cancers (e.g., endometrial, and ovarian cancers) from a biological sample (e.g., a tissue sample (e.g., cervical tissue), a blood sample, a plasma sample, a serum sample, a whole blood sample, a secretion sample (e.g., cervical secretion, vaginal secretion), an organ secretion sample, a CSF sample, a saliva sample, a urine sample, or a stool sample).
    Type: Application
    Filed: March 4, 2022
    Publication date: February 15, 2024
    Inventors: William R. Taylor, Dougias W. Mahoney, John B. Kisiel, David A. Ahlquist
  • Detecting gastric neoplasm
    Patent number: 11859254
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as gastric cancer.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: January 2, 2024
    Assignees: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, Exact Sciences Corporation
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Hatim T. Allawi
  • DETECTING PROSTATE CANCER
    Publication number: 20230416840
    Abstract: Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
    Type: Application
    Filed: May 24, 2023
    Publication date: December 28, 2023
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi
  • Detecting neoplasm
    Patent number: 11821039
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: November 21, 2023
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: David A. Ahlquist, John B. Kisiel, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
  • DETECTING NON-HODGKIN LYMPHOMA
    Publication number: 20230357852
    Abstract: Provided herein is technology for cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of non-Hodgkin lymphoma (NHL) and NHL subtypes (e.g., diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, mantle cell lymphoma, marginal zone lymphoma, peripheral T-cell lymphoma).
    Type: Application
    Filed: August 18, 2021
    Publication date: November 9, 2023
    Inventors: John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, William R. Taylor, Hatim T. Allawi, Viatcheslav E. Katerov
  • DETECTING NEOPLASM
    Publication number: 20230272482
    Abstract: This document relates to methods and materials for detecting premalignant and malignant neoplasms. For example, methods and materials for determining whether or not a stool sample from a mammal contains nucleic acid markers or polypeptide markers of a neoplasm are provided.
    Type: Application
    Filed: December 6, 2022
    Publication date: August 31, 2023
    Inventors: William R. Taylor, Jonathan J. Harrington, Patrick S. Quint, Hongzhi Zou, Harold R. Bergen, III, David I. Smith, David A. Ahlquist
  • Detecting ovarian cancer
    Patent number: 11702704
    Abstract: Provided herein is technology for ovarian cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of ovarian cancer and sub-types of ovarian cancer (e.g., clear cell ovarian cancer, endometrioid ovarian cancer, mucinous ovarian cancer, serous ovarian cancer).
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: July 18, 2023
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi, Michael W. Kaiser
  • Detecting prostate cancer
    Patent number: 11697853
    Abstract: Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: July 11, 2023
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi
  • DETECTING COLORECTAL NEOPLASIA
    Publication number: 20230212691
    Abstract: Provided herein is technology for colorectal neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of colorectal neoplasia in 1) individuals at, older or younger than 50 years of age, or 2) individuals having Lynch Syndrome.
    Type: Application
    Filed: December 21, 2022
    Publication date: July 6, 2023
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney
  • INGESTIBLE SAMPLING DEVICE
    Publication number: 20230190243
    Abstract: The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same.
    Type: Application
    Filed: April 16, 2021
    Publication date: June 22, 2023
    Inventors: Robert F. Eisele, Michael E. Williams, Prasad G. Iyer, Paul Marrione, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, John B. Kisiel, David A. Ahlquist
  • DETECTING PANCREATIC NEUROENDOCRINE TUMORS
    Publication number: 20230167506
    Abstract: Provided herein is technology for pancreatic neuroendocrine tumor screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of pancreatic neuroendocrine tumors.
    Type: Application
    Filed: May 4, 2021
    Publication date: June 1, 2023
    Inventors: David A. Ahlquist, John B. Kisiel, William R. Taylor, Douglas W. Mahoney, Shounak Majumder
  • DETECTING MELANOMA
    Publication number: 20230151433
    Abstract: Provided herein is technology for primary cutaneous melanoma screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of primary cutaneous melanoma.
    Type: Application
    Filed: May 4, 2021
    Publication date: May 18, 2023
    Inventors: David A. Ahlquist, John B. Kisiel, William R. Taylor, Douglas W. Mahoney, Calise K. Berger, Hatim T. Allawi, Viatcheslav Katerov
  • DETECTING GASTROINTESTINAL NEOPLASMS
    Publication number: 20230028856
    Abstract: Provided herein is technology for gastrointestinal neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of gastrointestinal neoplasm, and classifying the site location of such a gastrointestinal neoplasm (e.g., a colorectal region, a pancreaticobiliary region, a gastroesophageal region).
    Type: Application
    Filed: July 11, 2022
    Publication date: January 26, 2023
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Douglas W. Mahoney, Tracy C. Yab
  • Detecting colorectal neoplasia
    Patent number: 11542557
    Abstract: Provided herein is technology for colorectal neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of colorectal neoplasia in 1) individuals at, older or younger than 50 years of age, or 2) individuals having Lynch Syndrome.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: January 3, 2023
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney
  • CHARACTERIZING METHYLATED DNA, RNA, AND PROTEINS IN SUBJECTS SUSPECTED OF HAVING LUNG NEOPLASIA
    Publication number: 20220403471
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as lung cancer.
    Type: Application
    Filed: August 27, 2020
    Publication date: December 22, 2022
    Inventors: Scott Morris, David Mallery, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos, Michael W. Kaiser, David A. Ahlquist, William R. Taylor, Douglas W. Mahoney
  • Detecting neoplasm
    Patent number: 11530449
    Abstract: This document relates to methods and materials for detecting premalignant and malignant neoplasms. For example, methods and materials for determining whether or not a stool sample from a mammal contains nucleic acid markers or polypeptide markers of a neoplasm are provided.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: December 20, 2022
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: William R. Taylor, Jonathan J. Harrington, Patrick S. Quint, Hongzhi Zou, Harold R. Bergen, III, David I. Smith, David A. Ahlquist
  • DETECTING ESOPHAGEAL DISORDERS
    Publication number: 20220349009
    Abstract: Provided herein is technology for screening for esophageal disorders, including but not limited to, Barrett's esophagus (BE). In particular, provided herein are methods, compositions, and related uses for detecting the presence or absence of esophageal disorders from a biological sample.
    Type: Application
    Filed: April 22, 2022
    Publication date: November 3, 2022
    Inventors: William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, John B. Kisiel, David A. Ahlquist, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos
  • DETECTING THE PRESENCE OR ABSENCE OF MULTIPLE TYPES OF CANCER
    Publication number: 20220243278
    Abstract: Provided herein is technology for screening multiple types of cancer from a biological sample, and particularly, but not exclusively, to methods, compositions, and related uses for simultaneously detecting the presence of multiple types of cancer (e.g., liver cancer, esophageal cancer, lung cancer, ovarian cancer, pancreatic cancer, gastric cancer, bladder cancer, breast cancer, cervical cancer, colorectal cancer, prostate cancer, renal cancer, and uterine cancer) from a biological sample (e.g., stool sample, tissue sample, organ secretion sample, CSF sample, saliva sample, blood sample, plasma sample or urine sample).
    Type: Application
    Filed: January 28, 2022
    Publication date: August 4, 2022
    Inventors: William R. Taylor, Hatim T. Allawi, Viatcheslav E. Katerov, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist