Abstract: In one aspect, a light module is disclosed, which includes a housing providing a hollow chamber extending from a proximal end to a distal end, and a lens positioned in the hollow chamber, where the lens has a lens body comprising an input surface for receiving light from a light source and an output surface through which light exits the lens body, said lens further comprising a collar at least partially encircling said lens body. The light module further includes at least one shoulder on which the lens collar can be seated for positioning the lens within the housing. A light source, e.g., an LED, is coupled to the hollow chamber, e.g., at its proximal end, for providing light to the lens. In some embodiments, an optical window is disposed in the hollow chamber and is optically coupled to the output surface of the lens such that the light exiting the lens passes through the optical window before exiting the light module. In some embodiments, the shoulder can be formed as part of the housing.

Abstract: Devices, systems, and methods for bone stabilization, especially ulna head stabilization. The stabilization system may include a bone plate having an elongated portion extending along a longitudinal axis between a proximal end and a distal end. The bone plate defines a plurality of through holes extending through the elongated portion. A plurality of fasteners are configured to extend through one or more of the plurality of through holes in the bone plate and configured to secure the bone plate to the bone. The proximal end of the elongate portion has an arcuate configuration.

Abstract: A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that express just one or a few immunoglobulin light chain variable domains from a limited repertoire in their germline. Methods for making bispecific antibodies having universal light chains using mice as described herein, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, and host cells are provided. Bispecific antibodies capable of binding first and second antigens are provided, wherein the first and second antigens are separate epitopes of a single protein or separate epitopes on two different proteins are provided.

Abstract: A troche mold assembly includes a cover defining a receiving area and a tray removably positioned in the receiving area. The tray includes a frame having a top side and a bottom side opposite from the top side. The frame defines a plurality of cells, and each cell is configured to receive a medicament. The tray also includes a plurality of buttons. Each button is within a corresponding cell and is between the top side and the bottom side of the frame. In some aspects, wherein each button includes a center portion, a first hinge line adjacent to the cell wall, and a second hinge line between the first hinge line and the center portion. In various aspects, the cover includes a locating rib, and the tray is removably positioned within the receiving area such that the locating rib contacts the top side of the frame.

Abstract: The present disclosure relates to optical devices and systems, specifically those related to light detection and ranging (LIDAR) systems. An example device includes a shaft defining a rotational axis. The shaft includes a first material having a first coefficient of thermal expansion. The device also includes a rotatable mirror disposed about the shaft. The rotatable mirror includes a multi-sided structure having an exterior surface and an interior surface. The multi-sided structure includes a second material having a second coefficient of thermal expansion. The second coefficient of thermal expansion is different from the first coefficient of thermal expansion. The multi-sided structure also includes a plurality of reflective surfaces disposed on the exterior surface of the multi-sided structure. The multi-sided structure yet further includes one or more support members coupled to the interior surface and the shaft.

Abstract: A method for modifying a repeat interval of a locator beacon is described. The method includes transmitting repeatedly, by a beacon transmitter, a first advertising beacon signal through a first number of transmission repetitions spaced at a first repeat interval. The method further includes transmitting repeatedly, by the beacon transmitter, a second advertising beacon signal through a second number of transmission repetitions at a second repeat interval, wherein the second advertising beacon signal includes an identifier that provides identification of the beacon transmitter and user information. The method further includes receiving a modification instruction from a user device. The modification instruction is configured to modify the first repeat interval into a third repeat interval. The method also includes transmitting repeatedly, by a beacon transmitter, the first beacon signal through the first number of transmission repetitions spaced at the third repeat interval.

Abstract: Disclosed herein are systems, methods, and devices for facilitating officials during a sporting event. According to one embodiment, a device is disclosed including a processor, a memory electrically coupled with the processor, a microphone interface electrically coupled with the processor, a user interface electrically coupled with the processor, a haptic feedback device electrically coupled with the processor; and a wireless transceiver electrically coupled with the processor.

Abstract: A cover for a container that includes a lid portion and a collar element. The lid portion having a main body section surrounded by a peripheral sealing shoulder. The collar element having a peripheral collar sealing shoulder that includes a collar groove and wherein the lid portion is connected to the collar portion through a hinge element. The lid portion, collar element and hinge portion are formed as a unitary structure and the lid portion articulates from an open positon in which it is spaced apart from the collar element to a closed position wherein the peripheral bead sealing shoulder of the lid portion engages with the peripheral collar sealing shoulder of the collar element.

Abstract: A system for generating a user interface described herein can include a processor to detect a type of the system based on hardware components residing within the system or coupled to the system and determine a user interface manager to execute based on the type of the system. The processor can also execute the user interface manager to generate a user interface for the system, wherein the type of the user interface manager comprises a plurality of rules to indicate a layout of the user interface.

Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Abstract: An information handling system includes a bottom case and a wireless charging puck. The bottom case includes a bay. The wireless charging puck fits into the bay, and is detachable from the bottom case. When the wireless charging puck is fitted into the bay, the wireless charging puck is configured as a power receiving unit to receive wireless power. When the wireless charging puck is detached from the bay, the wireless charging puck is configured as a power transmitting unit to provide wireless power to an external device.

Abstract: The present disclosure relates to systems and methods for ML model feature selection and transformation. Specifically, the system and method Include receiving information and data from a network having resources; implementing feature selection on one or more network Machine Learning (ML) models, such that each is a pipeline of a plurality of functions to control the resources and with specified interfaces to other control applications; utilizing one or more feature graph engines (FGEs) which creates one or more feature graphs, from the information and data, as a functional component to derive a design-time set of feature vector for a specific context, each feature graph represents network layer representations in the network which includes multiple layers; and implementing changes to the one or more feature graphs based on any run-time updates from the pipeline.

Abstract: Systems and methods for network-based ultrasound imaging are provided, which can include a number of features. In some embodiments, an ultrasound imaging system images an object with three-dimensional unfocused pings and obtains digital sample sets from a plurality of receiver elements. A sub-set of the digital sample sets can be electronically transferred to a remote server, where the sub-set can be beamformed to produce a series of two-dimensional image frames. A video stream made up of the series of two-dimensional images frames can then be transferred from the remote server to a display device.

Abstract: A hearing assistance system is disclosed that comprises a hearing assistance device configured to reproduce sounds and to assist a person to hear the sounds, the hearing assistance device including a left hearing assistance device and a right hearing assistance device, and a computing device in communication with the hearing assistance device. The computing device interacts with the hearing assistance device to implement a fitting mode wherein the hearing assistance device is caused to generate fitting sounds usable to evaluate whether the left and right hearing devices are properly fitted into respective left and right ears of the person. The computing device produces a communication indicative of whether the left and right hearing assistance devices are properly fitted into respective left and right ears of the person.

Abstract: Using a natural language (NL) latent presentation in the automated conversion of source code from a base programming language (e.g., C++) to a target programming language (e.g., Python). A base-to-NL model can be used to generate an NL latent representation by processing a base source code snippet in the base programming language. Further, an NL-to-target model can be used to generate a target source code snippet in the target programming language (that is functionally equivalent to the base source code snippet), by processing the NL latent representation. In some implementations, output(s) from the NL-to-target model indicate canonical representation(s) of variables, and in generating the target source code snippet, technique(s) are used to match those canonical representation(s) to variable(s) of the base source code snippet. In some implementations, multiple candidate target source code snippets are generated, and a subset (e.g., one) is selected based on evaluation(s).

Abstract: A variable length headless compression screw insertion system includes a compression screw and a driver assembly for driving the compression screw into a bone. The compression screw has a bone screw and a compression sleeve coupled to the bone screw. The bone screw includes a proximal end having an external threading threadably received in the compression sleeve, and the compression sleeve includes a proximal end having a predefined drive feature and an external threading. The driver assembly includes a sleeve coupler adapted to threadably receive the external threading of the compression sleeve. A ram driver is coupled to the sleeve coupler and has a predetermined length such that its distal end is shaped to contact the proximal end of the bone screw to prevent translation of the bone screw relative to the compression sleeve.

Abstract: Systems, methods, and computer-readable media are described for compact radar systems. In some examples, a compact radar system can include a first set of transmit antennas, a second set of receive antennas, one or more processors, and at least one computer-readable storage medium storing computer-executable instructions which, when executed by the one or more processors, cause the radar system to coordinate digital beam steering of the first set of transmit antennas and the second set of receive antennas, and coordinate digital beam forming with one or more of the second set of receive antennas to detect one or more objects within a distance of the radar system.

Abstract: Pharmaceutically acceptable salts of 5-methoxy-N,N-dimethyltryptamine are described, as well as compositions/formulations and uses thereof as a medicament.

Abstract: The disclosure provides methods, treatments and materials for enhancing the effect of an adenosine A2 receptor agonist in the treatment, mitigation or prophylaxis of a disease or condition characterized by inotropic and/or lusitropic dysfunction, and/or enhancing adenosine A2 receptor function in the treatment, mitigation or prophylaxis of a disease or condition characterized by impaired adenosine A2 receptor function, comprising administration of an effective amount of a PDE1 inhibitor to a patient in need thereof, for example a patient suffering from heart failure.